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    PTPS-BASED VACCINES AGAINST CANCER
    1.
    发明申请
    PTPS-BASED VACCINES AGAINST CANCER 审中-公开
    基于PTPS的疫苗对抗癌症

    公开(公告)号：WO2017149118A1

    公开(公告)日：2017-09-08

    申请号：PCT/EP2017/055004

    申请日：2017-03-03

    申请人： INSTITUT GUSTAVE ROUSSY

    发明人： APCHER, Sébastien ,  FAHRAEUS, Robin ,  YAMAZAKI, Takahiro ,  PIERSON, Alison ,  BOULPICANTE, Mathilde

    IPC分类号： A61K39/00

    摘要： The present invention relates to the field of medicine. It more particularly relates to peptides, microvesicles containing such peptides, compositions containing same, in particular vaccine, and methods for stimulating an immune response in a subject.

    摘要翻译： 本发明涉及医学领域。 本发明更具体地涉及肽，包含此类肽的微泡，包含其的组合物，特别是疫苗，以及刺激受试者的免疫应答的方法。

    COMPOUNDS, COMPOSITION AND USES THEREOF FOR TREATING CANCER
    2.
    发明申请
    COMPOUNDS, COMPOSITION AND USES THEREOF FOR TREATING CANCER 审中-公开

    公开(公告)号：WO2018189210A1

    公开(公告)日：2018-10-18

    申请号：PCT/EP2018/059213

    申请日：2018-04-11

    申请人： INSTITUT GUSTAVE ROUSSY

    发明人： APCHER, Sébastien ,  PIERSON, Alison ,  BOULPICANTE, Mathilde ,  DOLOR, Renko, Zafiarisoa ,  ALAMI, Mouad ,  DARRIGRAND, Romain

    IPC分类号： C07D311/30 ,  A61K31/352 ,  A61P35/00

    摘要： The present invention relates to the fields of medicine and cancer treatment. The invention more specifically relates to new compounds which are typically for use as a medicament. In particular, the invention relates to the use of these new compounds for increasing the presentation, typically the production and presentation, of Pioneer Translation Products (PTPs)-derived antigens by cancer cells in a subject, and inducing or stimulating an immune response in the subject. The present disclosure also relates to uses of such compounds, in particular to prepare a pharmaceutical composition and/or to allow or improve the efficiency of a cancer therapy in a subject in need thereof. The invention also discloses methods for preventing or treating cancer, cancer metastasis and/or cancer recurrence in a subject. The present invention in addition provides kits suitable for preparing a composition according to the present invention and/or for implementing the herein described methods.