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公开(公告)号:WO2022251346A1
公开(公告)日:2022-12-01
申请号:PCT/US2022/030903
申请日:2022-05-25
Applicant: JUNO DIAGNOSTICS, INC.
Inventor: VAN DEN BOOM, Dirk , EHRICH, Mathias , NGUYEN, Michael Van , ELLISON, Christopher , DOMENIGHINI, Jeffery William , CERIANI, Dylann Duncan , BUCHANAN, Kristopher Scott , SMITH, Michael Gordon
Abstract: Provided herein are devices and methods for extracting blood plasma from ultra-low volumes of blood. In some cases, the devices and methods use positive pressure to force a blood sample through a filter or a membrane. In some cases, the devices and methods use centrifugation to force a blood sample through a filter or a membrane. The devices and methods disclosed herein are suitable for the preparation of high-quality samples containing cell-free nucleic acids.