公开(公告)号：WO2019180194A1

公开(公告)日：2019-09-26

申请号：PCT/EP2019/057215

申请日：2019-03-22

Applicant: VIB VZW ,  UNIVERSITEIT GENT ,  KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D

Inventor： HOSTE, Ester ,  MEES, Maarten ,  THIELEMANS, Wim

IPC: A61K31/704 ,  A61K9/00 ,  A61P17/02

Abstract: The present invention relates to compositions and methods for tissue regeneration, particularly for treating skin lesions, such as wounds. The invention provides topical plasters and wound healing compositions. Specifically, the invention provides hydrogels compositions of glycyrrhizinic acid analogues. The compositions and methods of the invention are useful especially for assisting the process of wound healing, particularly chronic open lesions that are slow to heal or resistant to healing.

公开(公告)号：WO2023275386A1

公开(公告)日：2023-01-05

申请号：PCT/EP2022/068334

申请日：2022-07-01

Applicant: KATHOLIEKE UNIVERSITEIT LEUVEN

Inventor： THIELEMANS, Wim ,  RUBIO ARIAS, Jose Jonathan

IPC: C08J11/16 ,  C08J2300/00 ,  C08J2367/00 ,  C08J2369/00 ,  C08J2377/00 ,  C08J2467/00 ,  C08J2469/00 ,  C08J2477/00

Abstract: In accordance with the purpose of the invention, as embodied and broadly described herein, the invention is broadly drawn to the use of an alcoholic medium, for instance methanol medium with an alkaline, for instance an alkali hydroxide, as 5depolymerization agent without any further addition of organic solvents under microwave action (heating) to achieve almost instantaneous, for instance within 1 – 13 minutes, for almost 100%, for instance 98 – 99,9 %, depolymerization of polyethylene terephthalate structures or polycarbonate structures of any suitable shape and morphology such as flakes, fibers, powder, sheet, pellet, spheres, pearls, dendrites, discs or any other three-0dimensional shape with a micrometric or millimetric dimension, singly or in combination if these are millinized structures, microsized structures, structures having a thickness up to 5 mm or structures having a maximum dimension of not more than 10 mm.