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公开(公告)号：WO2019002697A1
公开(公告)日：2019-01-03
申请号：PCT/FI2018/050522
申请日：2018-06-29
Applicant: LABMASTER OY , BIOMETRO CO LTD.
Inventor： PAVLOV, Andrei , KORPELA, Timo , WAHLROOS, Tony
Abstract: Electrochemiluminescence (ECL) device comprising a reaction cavity containing a solution (aqueous), an anode, a cathode covered by a thin insulating film barrier, and an active layer capable of producing ECL photons; an electrical pulse generator for injecting highly energetic or hot electrons into the solution via the anode and cathode; a photon emission sensor for detecting ECL photons; a sensor for measuring electron flow to the reaction cavity over tunneling through the insulating film barrier and solution; a sensor for measuring electron flow at a distance of 50-500 nm from the cathode surface; and an adaptive system configured to adjust, via a feedback loop based on measurements of the photon emission sensor and the electron flow sensors, control parameters, in particular amplitude, duration, frequency, and DC offset of voltage pulses, of the electrical pulse generator so as to obtain a maximum integrated specific ECL light output.
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公开(公告)号：WO2019002698A1
公开(公告)日：2019-01-03
申请号：PCT/FI2018/050523
申请日：2018-06-29
Applicant: LABMASTER OY , BIOMETRO CO LTD.
Inventor： PAVLOV, Andrei , KORPELA, Timo , WAHLROOS, Tony
Abstract: A device for generating a homogeneous flux of hot electrons in an aqueous solution comprises a cathode electrode (52) and first and second control electrodes (53, 54) on a substrate (51) surface, an anode electrode (57), a resistive barrier layer (55) on the cathode electrode, an isolation layer (61) between the control electrodes and the anode electrode, and an aqueous sensing layer (56) above the barrier layer, all said electrodes being connected to electronic circuitry, the control electrodes creating a lateral electro-static field and the anode electrode creating a vertical electro-magnetic field across the barrier layer, wherein hot electrons are generated by electric cathodic pulses, the hot electrons gain kinetic energy by moving laterally in the lateral electrostatic-field, and the lateral movement is changed to a vertical movement by cathodic voltage pulses providing change of lateral momentum of an electron to vertical momentum, whereby hot electrons with sufficient energy tunnel the barrier layer.
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公开(公告)号：WO2018096206A1
公开(公告)日：2018-05-31
申请号：PCT/FI2017/050797
申请日：2017-11-21
Applicant: LABMASTER OY
Inventor： PERÄLÄ, Petri , KORPELA, Timo , WAHLROOS, Tony , KORPELA, Saara
IPC: B01L3/00 , G01N33/543 , G01F11/10 , G01N21/03
Abstract: A lab-on-a-chip -device having macroscopic sliding components and a method to use the device is disclosed. The device allows measuring an exact predetermined volume of a sample and applying the measured sample on reagents, applying additional reagents on the sample, and measuring a biochemical or chemical reaction by recording a visual, fluorometric, colorimetric, spectrophotometric, luminometric and amperometric changes. The device enables chemical and biochemical tests requiring exact volumes to be conducted outside professional laboratory facilities. The device can be used in healthcare and in environmental applications. The device and the method are suitable for point of need situations.
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