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    ENDOVASCULAR CRYOTREATMENT CATHETER
    2.
    发明申请
    ENDOVASCULAR CRYOTREATMENT CATHETER 审中-公开

    公开(公告)号：WO2006017073A3

    公开(公告)日：2006-02-16

    申请号：PCT/US2005/023792

    申请日：2005-07-06

    Applicant: CRYOCATH TECHNOLOGIES INC. ,  LANE, Miriam

    Inventor： LANE, Miriam ,  ABBOUD, Marwan ,  MAHROUCHE, Rachid ,  MIHALIK, Teresa, Ann

    IPC: A61B18/18

    Abstract: An elongated catheter device (10) with a distal balloon (860) assembly is adapted for endovascular insertion. Coolant injected through the device may, in different embodiments, directly cool tissue contacting the balloon, or may cool a separate internal chamber. Plural balloons may be provided, wherein a secondary outer balloon (865) surrounds a primary inner balloon, the primary balloon being filled with coolant and acting as the cooling chamber, the secondary balloon being coupled to a vacuum return lumen (850) to serve as a robust leak containment device and thermal insulator around the cooling chamber. One or more sensors may be disposed between the balloons or the vacuum return lumen, to detect leaks and control the flow of fluid through the device. Examples of sensors include pressure and temperature sensors, optical sensors, magnetic flow switches and flow meters.

    DUAL INJECTION TUBE CRYOCATHETER AND METHOD FOR USING SAME
    3.
    发明申请
    DUAL INJECTION TUBE CRYOCATHETER AND METHOD FOR USING SAME 审中-公开
    双注射管结晶器及其使用方法

    公开(公告)号：WO2012015636A1

    公开(公告)日：2012-02-02

    申请号：PCT/US2011/044603

    申请日：2011-07-20

    Applicant: MEDTRONIC CRYOCATH LP ,  WITTENBERGER, Dan ,  LUECKGE, Claudia ,  LANE, Miriam

    Inventor： WITTENBERGER, Dan ,  LUECKGE, Claudia ,  LANE, Miriam

    IPC: A61B18/02

    CPC classification number: A61B18/02 ,  A61B2018/00166 ,  A61B2018/0022 ,  A61B2018/00642 ,  A61B2018/0212 ,  A61B2090/064

    Abstract: A medical device includes a catheter body having a first injection lumen, a second injection lumen, and an exhaust lumen, where the first injection lumen provides a fluid flow rate greater than a fluid flow rate provided by the second injection lumen; an expandable element coupled to the catheter body in fluid communication with the first and second injection lumens; a cryogenic fluid source in fluid communication with the first and second injection lumens; a valve in fluid communication with the first and second injection lumens to selectively allow fluid flow to at least one of the first and second injection lumens; a pressure sensor in fluid communication with an interior defined by the expandable element; and a controller in communication with the pressure sensor programmed to regulate fluid flow through the first injection lumen based at least in part on a signal from the pressure sensor.

    Abstract translation: 医疗装置包括具有第一注射腔，第二注射内腔和排气腔的导管主体，其中第一注射内腔提供大于由第二注射腔提供的流体流速的流体流速; 耦合到所述导管主体的可扩张元件，其与所述第一和第二注射腔流体连通; 与所述第一和第二注射腔流体连通的低温流体源; 与所述第一和第二注射腔流体连通的阀，以选择性地允许流体流向所述第一和第二注射腔中的至少一个; 与由可膨胀元件限定的内部流体连通的压力传感器; 以及与所述压力传感器通信的控制器，其被编程为至少部分地基于来自所述压力传感器的信号来调节通过所述第一喷射腔的流体流动。

    TISSUE ABLATION SYSTEM INCLUDING GUIDEWIRE WITH SENSING ELEMENT
    4.
    发明申请
    TISSUE ABLATION SYSTEM INCLUDING GUIDEWIRE WITH SENSING ELEMENT 审中-公开
    组织吸收系统，包括带传感元件的指南

    公开(公告)号：WO2006069013A1

    公开(公告)日：2006-06-29

    申请号：PCT/US2005/045989

    申请日：2005-12-16

    Applicant: CRYOCATH TECHNOLOGIES INC. ,  LANE, Miriam

    Inventor： LANE, Miriam ,  KANIA, Wlodzimierz ,  CARROLL, Sean ,  SKANES, Allan, Dr.

    IPC: A61B18/00 ,  A61M25/09

    CPC classification number: A61B5/6851 ,  A61B5/6856 ,  A61B18/02 ,  A61B18/04 ,  A61B18/1492 ,  A61B18/18 ,  A61B2017/00026 ,  A61B2017/00044 ,  A61B2017/00084 ,  A61B2017/00243 ,  A61B2017/00292 ,  A61B2017/00867 ,  A61B2018/00214 ,  A61B2018/0212 ,  A61B2018/1407

    Abstract: A tissue ablation system for ablating human tissue wherein sensing and ablation procedures are performed and controlled independently. A sensing wire is positioned distally to the ablation region and is adapted to pass thorough the ablation device such that it may move with or independently of the ablation device without obstructing the surface tissue interface of the ablation energy. The ablation device can ablate a substantial portion of a circumferential region of tissue, for example at or near the location where the pulmonary vein extends from the atrium. The tissue ablation system comprises an ablation device comprised of an elongated catheter with a proximal region and a distal region and an ablation element located proximate the distal region of the catheter. A sensing device having an elongated body with a proximal portion and a distal portion is adapted to be positioned within a vessel at or near a vessel ostium, wherein the sensing device is adapted to be slidably received within a lumen of the ablation device. The sensing device, a guide wire for example, may be shaped in various configurations to allow sensing device such as electrodes disposed thereon to contact the vessel wall near the ablation region. In this fashion, the sensing and ablation procedures are de-coupled such that the sensing device does not interfere or obstruct the ablation member's interface with the tissue

    Abstract translation: 一种用于消融人体组织的组织消融系统，其中感测和消融程序被独立地执行和控制。 感测线位于远离切割区域并且适于穿过消融装置，使得其可以与消融装置移动或独立于消融装置移动，而不会阻碍消融能量的表面组织界面。 消融装置可以消除组织的周边区域的大部分，例如在肺静脉从心房延伸的位置处或附近。 组织消融系统包括消融装置，其包括具有近端区域和远侧区域的细长导管和位于导管远侧区域附近的消融元件。 具有具有近端部分和远端部分的细长主体的感测装置适于被定位在血管口中或附近的血管内，其中感测装置适于可滑动地容纳在消融装置的内腔内。 感测装置，例如引导线可以被成形为各种构造，以允许诸如设置在其上的电极的感测装置接触消融区域附近的血管壁。 以这种方式，感测和消融程序被去耦合，使得感测装置不干扰或阻碍消融构件与组织的界面

    DISTAL COOLING DISTRIBUTION SYSTEM FOR A MEDICAL DEVICE
    5.
    发明申请
    DISTAL COOLING DISTRIBUTION SYSTEM FOR A MEDICAL DEVICE 审中-公开

    公开(公告)号：WO2007145759A3

    公开(公告)日：2007-12-21

    申请号：PCT/US2007/011590

    申请日：2007-05-15

    Applicant: CRYOCATH TECHNOLOGIES INC. ,  LANE, Miriam

    Inventor： LANE, Miriam ,  HU, Yixin ,  TZONEV, Vladimir ,  MIHALIK, Teresa, Ann ,  THIBAULT, Benoit ,  WITTENBERGER, Dan ,  PETRE, Cristian

    IPC: A61B18/02

    Abstract: The present invention may include a medical device having a handle, a catheter coupled to the handle, and an expandable element coupled to the catheter. The medical device may also include first and second elongate bodies that traverse a length of the handle and catheter. A housing may be disposed within the handle, with the housing defines a first opening able to receive a portion of the first elongate body, a second opening able to receive a portion of the second elongate body, and a third opening opposite the first and second openings able to receive a portion of both the and second elongate bodies. A separation element may be disposed within the housing, with the separation element defining a path able to receive a portion of the second elongate body, and whereby a portion of the first elongate body forms a loop around the separation element.

    ENDOVASCULAR CRYOTREATMENT CATHETER
    6.
    发明申请
    ENDOVASCULAR CRYOTREATMENT CATHETER 审中-公开
    内膜切开导管

    公开(公告)号：WO2003020334A2

    公开(公告)日：2003-03-13

    申请号：PCT/US2002/027627

    申请日：2002-08-29

    Applicant: LANE, Miriam

    Inventor： LANE, Miriam ,  CAPUANO, Leonilda ,  HOLTAN, David ,  LALONDE, Jean-Pierre ,  LÜCKGE, Claudia ,  PAEGARD, Jean-Luc ,  ABBOUD, Marwan ,  ALASMAR, Johny ,  BENRABAH, Abderrahim ,  CHEN, Ken ,  LEHMANN, John, W. ,  MARCHAND, Philippe ,  MARTIN, Robert ,  MILDER, Frederic, L. ,  NAHON, Daniel

    IPC: A61M

    CPC classification number: A61B18/02 ,  A61B2017/22001 ,  A61B2017/22051 ,  A61B2017/22054 ,  A61B2017/22069 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61B2018/0268

    Abstract: An elongated catheter device with a distal balloon assembly is adapted for endovascular insertion. Coolant injected through the device may, in different embodiments, directly cool tissue contacting the balloon, or may cool a separate internal chamber. In the first case, the coolant also inflates the balloon, and spent coolant is returned to the handle via a return passage extending through the body of the catheter.Plural balloons may be provided, wherein a secondary outer balloon surrounds a primary inner balloon, the primary balloon being filled with coolant and acting as the cooling chamber, the secondary balloon being coupled to a vacuum return lumen to serve as a robust leak containment device and thermal insulator around the cooling chamber. Various configurations, such as surface modification of the balloon interface, or placement of particles, coatings, or expandable meshes or coils in the balloon interface, may be employed to achieve this function.

    Abstract translation: 具有远端球囊组件的细长导管装置适于血管内插入。 在不同的实施例中，通过装置注入的冷却剂可以直接冷却接触气囊的组织，或者可以冷却单独的内部室。 在第一种情况下，冷却剂还使气囊膨胀，并且废弃的冷却剂经由延伸穿过导管主体的返回通道返回到手柄。可以提供柔性气囊，其中次级外气囊围绕主内气球， 初级球囊充满冷却剂并充当冷却室，次级气球与真空回流腔相连，用作强制性的泄漏容纳装置和围绕冷却室的绝热体。 可以采用各种构造，例如球囊界面的表面改性，或者在气球界面中放置颗粒，涂层或可膨胀的网孔或线圈，以实现该功能。

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