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公开(公告)号:WO2017009790A1
公开(公告)日:2017-01-19
申请号:PCT/IB2016/054185
申请日:2016-07-13
发明人: MERKX-JACQUES, Alexandra , WOODHALL, David , SCAIFE, Mark , ARMENTA, Roberto E. , MUISE, Denise , RASMUSSEN, Holly , BENJAMIN, Jeremy
CPC分类号: C12N9/92 , C07K14/40 , C07K2319/21 , C12N9/1205 , C12Y207/01017 , C12Y503/01005
摘要: Provided herein are recombinant microorganisms having two or more copies of a nucleic acid sequence encoding xylose isomerase, wherein the nucleic acid encoding the xylose isomerase is an exogenous nucleic acid. Optionally, the recombinant microorganisms include at least one nucleic acid sequence encoding a xylulose kinase and/or at least one nucleic acid sequence encoding a xylose transporter. The provided recombinant microorganisms are capable of growing on xylose as a carbon source.
摘要翻译: 本文提供了具有两个或更多拷贝的编码木糖异构酶的核酸序列的重组微生物,其中编码木糖异构酶的核酸是外源核酸。 任选地,重组微生物包括编码木酮糖激酶和/或编码木糖转运蛋白的至少一个核酸序列的至少一个核酸序列。 所提供的重组微生物能够在作为碳源的木糖上生长。