公开(公告)号：WO2023037188A1

公开(公告)日：2023-03-16

申请号：PCT/IB2022/057848

申请日：2022-08-22

申请人： MEDTRONIC, INC.

发明人： GOODMAN, Jonathan T. ,  CHEN, Sean ,  SEETHAMRAJU, Kasyap V. ,  YUAN, Charlene X. ,  BAHULEKAR, Raman V. ,  KALSCHEUER, Joseph L.

IPC分类号： A61F2/00 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16

摘要： A surgical device includes a substrate and a first coating that covers at least a portion of the substrate. The first coating includes a first polymer. The first coating having antibiotics dispersed in the first polymer such that the first polymer releases the antibiotics as the first polymer degrades. A second coating covers at least a portion of the first coating. The second coating includes a second polymer. The second polymer includes an alginate. The second coating has a hemostatic agent dispersed in the second polymer such that the second polymer releases the hemostatic agent as the second polymer degrades. The hemostatic agent is selected from epinephrine, tranexamic acid, chitosan and oxidized regenerated cellulose. In some embodiments, systems and methods are disclosed.