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公开(公告)号:WO2017014865A1
公开(公告)日:2017-01-26
申请号:PCT/US2016/037330
申请日:2016-06-14
IPC分类号: A61K38/01 , A61K38/04 , A61K38/07 , A61K38/08 , C12N9/12 , A23L33/18 , A23L33/19 , A23L33/00 , A61P37/00
CPC分类号: A61K38/018 , A23L33/18 , A23L33/19 , A23L33/40 , A23V2002/00 , A61K31/202 , A61K31/702 , A61K31/716 , A61K35/74 , A61K35/741 , C07K14/4732 , C12N9/1205 , C12Y207/01 , A23V2200/30 , A23V2200/304 , A23V2200/32 , A23V2200/324 , A23V2250/00 , A23V2250/54246 , A23V2250/55 , A23V2300/00 , A23V2300/28 , A61K2300/00
摘要: A method for modulating a kinase by administering to a subject a nutritional composition comprising extensively hydrolyzed casein, extensively hydrolyzed casein fractions, or combinations thereof. A modulated kinase may be a kinase that regulates inflammatory signaling, immune tolerance, metabolic signaling, cell cycle and growth factor signaling. The nutritional composition may dose-dependently inhibit a range of serine, threonine and tyrosine kinases.
摘要翻译: 通过向受试者施用包含广泛水解的酪蛋白,广泛水解的酪蛋白级分或其组合的营养组合物来调节激酶的方法。 调节的激酶可以是调节炎症信号,免疫耐受,代谢信号,细胞周期和生长因子信号传导的激酶。 营养组合物可以剂量依赖地抑制丝氨酸,苏氨酸和酪氨酸激酶的范围。