-
公开(公告)号：WO2023057386A1
公开(公告)日：2023-04-13
申请号：PCT/EP2022/077465
申请日：2022-10-03
IPC分类号： A61K31/7004 , A61K31/7012 , A61K31/702 , A61K35/00 , A61K9/00 , A61K45/06 , A61P9/00 , A61P25/00 , A61P25/18 , A61P25/28 , A61P43/00 , A61K35/745
摘要： The present application relates to compositions comprising sialic acid and/or fucose to enhance cognitive function by promoting differentiation of oligodendrocyte precursor cells into mature, myelinating oligodendrocytes.
-
2.发明申请
公开(公告)号：WO2021116236A1
公开(公告)日：2021-06-17
申请号：PCT/EP2020/085391
申请日：2020-12-09
发明人： CHICHLOWSKI, Maciej Witalis , GROSS, Gabriele , LI, Qian , MARIA, Sarah Diane , PHILLIPS, Shay Cristine , VAN DIEPEN, Janna Alida , VAN TOL, Eric Alexander Franciscus
摘要： The present application provides nutritional compositions comprising human milk oligosaccharides, for use in providing nutrition to infants at different age stages.
-
公开(公告)号：WO2017095609A1
公开(公告)日：2017-06-08
申请号：PCT/US2016/061735
申请日：2016-11-14
发明人： LOVE, Margo E.,
IPC分类号： B65D51/28
CPC分类号： B65D51/2828 , A61J9/00 , B65D47/247 , B65D51/18 , B65D51/2807 , B65D51/2821 , B65D2251/0018 , B65D2251/0078
摘要： A method and apparatus for powder dosing a nutritional composition may include a container body and a closure removably coupled to the container body. A nutritive substance may be retained between an upper portion of the container body and the closure. The nutritive substance may be released and mixed with the contents of the container body prior to consumption. The nutritive substance may be sealed prior to use in order to prevent contamination of the nutritive substance.
摘要翻译： 用于粉末计量营养组合物的方法和设备可以包括容器主体和可移除地联接到容器主体的封闭件。 营养物质可以保持在容器主体的上部和封闭件之间。 在食用之前，营养物质可以被释放并与容器主体的内容物混合。 使用前可将营养物质密封，以防止营养物质的污染。
-
公开(公告)号：WO2017014865A1
公开(公告)日：2017-01-26
申请号：PCT/US2016/037330
申请日：2016-06-14
IPC分类号： A61K38/01 , A61K38/04 , A61K38/07 , A61K38/08 , C12N9/12 , A23L33/18 , A23L33/19 , A23L33/00 , A61P37/00
CPC分类号： A61K38/018 , A23L33/18 , A23L33/19 , A23L33/40 , A23V2002/00 , A61K31/202 , A61K31/702 , A61K31/716 , A61K35/74 , A61K35/741 , C07K14/4732 , C12N9/1205 , C12Y207/01 , A23V2200/30 , A23V2200/304 , A23V2200/32 , A23V2200/324 , A23V2250/00 , A23V2250/54246 , A23V2250/55 , A23V2300/00 , A23V2300/28 , A61K2300/00
摘要： A method for modulating a kinase by administering to a subject a nutritional composition comprising extensively hydrolyzed casein, extensively hydrolyzed casein fractions, or combinations thereof. A modulated kinase may be a kinase that regulates inflammatory signaling, immune tolerance, metabolic signaling, cell cycle and growth factor signaling. The nutritional composition may dose-dependently inhibit a range of serine, threonine and tyrosine kinases.
摘要翻译： 通过向受试者施用包含广泛水解的酪蛋白，广泛水解的酪蛋白级分或其组合的营养组合物来调节激酶的方法。 调节的激酶可以是调节炎症信号，免疫耐受，代谢信号，细胞周期和生长因子信号传导的激酶。 营养组合物可以剂量依赖地抑制丝氨酸，苏氨酸和酪氨酸激酶的范围。
-
5.发明申请
公开(公告)号：WO2017011133A1
公开(公告)日：2017-01-19
申请号：PCT/US2016/037774
申请日：2016-06-16
发明人： AO, Zihua, , BERSETH, Carol Lynn, , COBB, Patricia, , GONZALEZ, Juan M., , LONDON, Elisha, , NGUYEN, Minhthy, , RICHARDS, James David, , RUDOLPH, Colin, , ALVEY, John D., , MALDONADO, Yadilka,
IPC分类号： A23L33/00 , A23L33/115 , A23L33/19 , A23L33/20
CPC分类号： A23C17/00 , A23L33/10 , A23L33/115 , A23L33/12 , A23L33/15 , A23L33/17 , A23L33/19 , A23L33/20 , A23L33/21 , A23L33/40 , A23V2002/00 , A61K31/19 , A61K31/202 , A61K31/7004 , A61K31/702 , A61K31/714 , A61K31/715 , A61K35/20 , A61K38/482 , C12Y304/21
摘要： A method for enhancing cognitive development in a pediatric subject involving administering to the subject a nutritional composition which includes up to 7 g/100 Kcal of a fat or lipid; up to 5 g/100 Kcal of a protein or protein equivalent source; 0.25 g/100 Kcal to 16 g/100 Kcal of buttermilk; 5 mg/100 Kcal to 90 mg/100 Kcal of a source of long chain polyunsaturated fatty acid; and 0.015 g/100 Kcal to 1.5 g/100 Kcal of a prebiotic.
摘要翻译： 一种用于增强儿科受试者认知发展的方法，包括对受试者施用包含高达7g / 100Kcal脂肪或脂质的营养组合物; 高达5 g / 100 Kcal的蛋白质或蛋白质当量来源; 0.25g / 100Kcal至16g / 100Kcal的酪乳; 5 mg / 100 Kcal至90 mg / 100 Kcal长链多不饱和脂肪酸源; 和0.015g / 100Kcal至1.5g / 100Kcal的益生元。
-
6.发明申请EXPANDED BED ADSORPTION METHODS FOR ISOLATION OF BASIC MILK PROTEINS INCLUDING LACTOFERRIN 审中-公开用于分离含有LACTOFERRIN的基本乳清蛋白的膨化床吸附方法
公开(公告)号：WO2015009400A1
公开(公告)日：2015-01-22
申请号：PCT/US2014/043328
申请日：2014-06-20
CPC分类号： A23J1/20 , A23J1/202 , A23J1/205 , C07K14/47 , C07K14/79 , C12N9/0065 , C12Y111/01007
摘要： The present disclosure relates to improved expanded bed adsorption processes for isolating proteins from milk sources. In particular embodiments, the present disclosure provides a process for isolating a milk protein, such as lactoferrin, from a milk source comprising establishing an expanded bed adsorption column comprising a particulate matrix, applying a milk source to the matrix, and eluting the lactoferrin from the matrix with an elution buffer comprising about 0.3 to about 2.0 M sodium chloride.
摘要翻译： 本公开涉及用于从乳源分离蛋白质的改进的扩展床吸附方法。 在具体实施方案中，本公开提供了从奶源中分离乳蛋白（例如乳铁蛋白）的方法，包括建立包含颗粒基质的膨胀床吸附柱，将乳源施加到基质上，并从乳源蛋白 基质，洗脱缓冲液包含约0.3至约2.0M氯化钠。
-
公开(公告)号：WO2014150566A1
公开(公告)日：2014-09-25
申请号：PCT/US2014/023630
申请日：2014-03-11
发明人： HONDMANN, Dirk, , VAN TOL, Eric A.F., , GROSS, Gabriele, , SCHOEMAKER, Marieke H., , LAMBERS, Teartse Tim,
CPC分类号： A61K38/018
摘要： The present disclosure provides a method for reducing the risk of autoimmune disease by administering a composition comprising peptides selected from a casein hydrolysate. Such a composition, may reduce the symptoms of autoimmune disease and may be a treatment for autoimmune disease, especially type 1 diabetes. Preferably, the hydrolysate consists of peptides with a molecular weight of more than 500 Da.
摘要翻译： 本公开提供了通过施用包含选自酪蛋白水解产物的肽的组合物来降低自身免疫疾病风险的方法。 这种组合物可以减少自身免疫疾病的症状，并且可以是自身免疫疾病，特别是1型糖尿病的治疗。 优选地，水解产物由分子量大于500Da的肽组成。
-
公开(公告)号：WO2014143481A1
公开(公告)日：2014-09-18
申请号：PCT/US2014/016070
申请日：2014-02-12
发明人： WITTKE, Anja , BANAVARA, Dattatreya
CPC分类号： A23L1/296 , A23L29/015 , A23L29/035 , A23L33/16 , A23L33/19 , A23L33/26 , A23L33/40 , A23V2002/00 , A23V2200/32 , A23V2200/06 , A23V2200/3202 , A23V2200/3204 , A23V2250/1578
摘要： The present disclosure is directed to methods for supporting resistance to bacterial growth in the gastrointestinal tract of a subject, particularly in that of a human infant. In certain embodiments, the method comprises administering to a subject a nutritional composition that has a low buffer strength, wherein administration of said nutritional composition decreases the bacterial counts of bacteria selected from the group consisting of Enteropathogenic E. coli (EPEC), Enteroaggregative E. coli (EAEC), Cronobacter sakazakii, Salmonella enterica , and combinations thereof in the subject's gastrointestinal tract. This disclosure further relates to the manufacture and use of low-buffer nutritional compositions in methods for modulating gastric acidity and/or in methods for enhancing the rate of gastric emptying in a subject, each method comprising a step of administering at least one of said low-buffer nutritional compositions to the subject.
摘要翻译： 本公开涉及用于支持对受试者的胃肠道中的细菌生长的抗性的方法，特别是对于婴儿。 在某些实施方案中，所述方法包括对受试者施用具有低缓冲强度的营养组合物，其中所述营养组合物的施用降低了选自肠病毒性肠杆菌（Enterec病原性大肠杆菌）（Entercathogenic E.coli）（EPEC），肠聚集体E. 大肠杆菌（EAEC），阪崎肠埃布杆菌，肠炎沙门氏菌及其组合在受试者的胃肠道中。 本公开还涉及在调节胃酸度的方法中和/或用于增强受试者胃排空速率的方法中制备和使用低缓冲营养组合物，每种方法包括施用至少一种所述低浓度 缓冲营养组合物。
-
9.发明申请NUTRITIONAL COMPOSITIONS CONTAINING AN ENRICHED LIPID FRACTION AND USES THEREOF 审中-公开含有丰富脂质分解的营养组合物及其用途
公开(公告)号：WO2014143469A1
公开(公告)日：2014-09-18
申请号：PCT/US2014/015775
申请日：2014-02-11
CPC分类号： A23L1/296 , A23C2240/05 , A23L33/115 , A23L33/12 , A23L33/135 , A23L33/19 , A23L33/40
摘要： The present disclosure relates to a nutritional composition comprising a fat source that includes an enriched lipid fraction derived from milk. The enriched lipid fraction may contain saturated fatty acids, trans-fatty acids, monounsaturated fatty acids, CLAs, BCFAs, cholesterol, milk fat globule membrane proteins, gangliosides, and mixtures thereof. The enriched lipid fraction may exhibit additive or synergistic beneficial health effects when consumed. The disclosure further relates to methods of providing a nutritional composition comprising an enriched lipid fraction to targeted subjects.
摘要翻译： 本公开涉及包含脂肪源的营养组合物，其包含来自牛奶的富集的脂质部分。 富集的脂质部分可以含有饱和脂肪酸，反式脂肪酸，单不饱和脂肪酸，CLA，BCFA，胆固醇，乳脂肪球膜蛋白，神经节苷脂及其混合物。 当消耗时，富集的脂质部分可能表现出增加的或协同的有益的健康影响。 本公开还涉及向目标受试者提供包含富集脂质部分的营养组合物的方法。
-
10.发明申请
公开(公告)号：WO2014109862A1
公开(公告)日：2014-07-17
申请号：PCT/US2013/074521
申请日：2013-12-12
IPC分类号： A23L1/30 , A23L1/29 , A61K31/164 , A61K31/685 , A61K31/688 , A61K31/7032 , A61K31/7068 , A61K31/7072
CPC分类号： A61K31/7072 , A23L33/115 , A23L33/12 , A23L33/40 , A61K31/07 , A61K31/164 , A61K31/685 , A61K31/688 , A61K31/7032 , A61K31/7068 , A61K2300/00
摘要： The present disclosure relates to nutritional compositions comprising a neurologic component, wherein, the neurologic component may promote brain and nervous system development and further provide neurological protection and repair. The neurologic component may include phosphatidylethanolamine, sphingomyelin, cytidine diphosphate-choline, ceramide, uridine, at least one ganglioside, and mixtures thereof. The disclosure further relates to methods of promoting brain and nervous system health by providing said nutritional compositions to target subjects, which includes pediatric subjects.
摘要翻译： 本公开内容涉及包含神经组分的营养组合物，其中神经学组分可促进脑和神经系统发育并进一步提供神经保护和修复。 神经学成分可包括磷脂酰乙醇胺，鞘磷脂，胞苷二磷酸胆碱，神经酰胺，尿苷，至少一种神经节苷脂，及其混合物。 本公开还涉及通过向包括儿科受试者在内的目标受试者提供所述营养组合物来促进脑和神经系统健康的方法。
-
-
-
-
-
-
-
-
-
搜索结果
74 条记录 (耗时 0.034 秒)
