公开(公告)号：WO2019101700A1

公开(公告)日：2019-05-31

申请号：PCT/EP2018/081830

申请日：2018-11-20

Applicant: NESTEC S.A.

Inventor： BOUTRY, Claire ,  BREUILLE, Denis ,  HORCAJADA, Marie,Noëlle

IPC: A23L33/105 ,  A61K36/9066 ,  A61K36/63 ,  A61P21/06 ,  A61P39/06

Abstract: A composition comprising at least one of oleuropein or curcumin can treat or prevent sarcopenia, reduce a loss of at least one of muscle quality or muscle mass, increase at least one of muscle quality or muscle mass, and/or improve recovery of at least one of muscle quality or muscle mass after muscle atrophy. The composition can be administered to an individual who is elderly and/or frail.

公开(公告)号：WO2017202939A1

公开(公告)日：2017-11-30

申请号：PCT/EP2017/062588

申请日：2017-05-24

Applicant: NESTEC S.A.

Inventor： HORCAJADA, Marie Noëlle ,  BREUILLE, Denis ,  BOUTRY, Claire ,  ROUGHEAD, Zamzam, Kabiry (Fariba)

IPC: A61K31/12 ,  A61K31/198 ,  A61K31/202 ,  A61K31/205 ,  A61K31/355 ,  A61K31/375 ,  A61K31/7008 ,  A61K31/7048 ,  A61K31/728 ,  A61K31/737 ,  A61K38/39 ,  A61K45/06 ,  A61P19/02 ,  A61P19/08 ,  A61P19/10

Abstract: A method of treating or preventing impaired mobility in an older adult includes administering to the older adult an effective amount of a composition containing at least one ingredient for cognitive ability, at least one ingredient for muscle and/or bone quality, and at least one ingredient for joint quality and/or functionality. The older adult can be an elderly individual and/or can have a condition that is one or more of frailty, pre-frailty, sarcopenia, recovering from sarcopenia, malnutrition, at risk of malnutrition, undergoing rehabilitation, and being scheduled to undergo rehabilitation, disorders impacting mobility such as osteoporosis, osteoarthritis, pre-osteoarthritis, osteopenia, cognitive decline. In a non-limiting example of the composition, the at least one ingredient for muscle and/or bone quality and the at least one ingredient for joint quality include a protein source, omega-3 fatty acids, and a polyphenol.

Abstract translation: 治疗或预防老年成人中流动性受损的方法包括向老年人施用有效量的组合物，所述组合物含有至少一种用于认知能力的成分，至少一种用于肌肉的成分和/或 骨质量，以及至少一种用于关节质量和/或功能性的成分。 年长的成年人可以是老年人，并且/或者可以具有一种或多种虚弱，脆弱，肌肉减少症，从肌肉减少症恢复，营养不良，营养不良，正在接受康复以及计划接受康复的一种或多种情况， 影响流动性的疾病如骨质疏松症，骨关节炎，前骨关节炎，骨质减少，认知衰退。 在组合物的非限制性实例中，用于肌肉和/或骨质量的至少一种成分和用于关节质量的至少一种成分包括蛋白质来源，ω-3脂肪酸和多酚。

公开(公告)号：WO2017085190A1

公开(公告)日：2017-05-26

申请号：PCT/EP2016/078014

申请日：2016-11-17

Applicant: NESTEC S.A.

Inventor： HORCAJADA, Marie Noëlle ,  MEMBREZ, Fanny ,  BREUILLE, Denis ,  BOUTRY, Claire

IPC: A23L33/105 ,  A23L29/00 ,  A61K31/05 ,  A61P21/06

CPC classification number: A23L33/105 ,  A23L33/12 ,  A23L33/17 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/12 ,  A61K31/352 ,  A61K31/7048 ,  A61K38/00 ,  A61K45/06 ,  A23V2200/316 ,  A23V2250/1868 ,  A23V2250/2116 ,  A23V2250/21168 ,  A23V2250/2117

Abstract: A composition comprising one or more polyphenols, such as oleuropein, rutin, curcumin or quercetin, can treat or prevent sarcopenia, reduce a loss of muscle functionality (e.g. muscle strength, gait speed, etc.), increase muscle functionality, and/or improve recovery of muscle functionality after muscle atrophy. The composition can be administered to an individual who is elderly and/or frail.

Abstract translation: 包含一种或多种多酚（例如橄榄苦苷，芦丁，姜黄素或槲皮素）的组合物可以治疗或预防肌肉减少症，减少肌肉功能性（例如肌肉力量，步态速度等）的损失， 增加肌肉功能，和/或改善肌肉萎缩后肌肉功能的恢复。 该组合物可以给予年老和/或虚弱的个体。