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1.发明申请
公开(公告)号：WO2020014652A1
公开(公告)日：2020-01-16
申请号：PCT/US2019/041674
申请日：2019-07-12
Applicant: NEW YORK UNIVERSITY
Inventor： KIRSHENBAUM, Kent , LOGAN, Susan , CRAVEN, Timothy , KASPER, Amanda , BONNEAU, Richard, A. , SCHNEIDER, Jeffrey, A.
IPC: A61K38/12 , A61K31/198 , A61K38/08
Abstract: Provided are peptoid-peptide macrocycles. The peptoid-peptide macrocycles may have inhibitory activity towards the Wnt signaling pathway. The Wnt signaling pathway is associated with cancer and other diseases and conditions. Such diseases include, for example, pulmonary fibrosis. Also described are methods of making the peptoid-peptide macrocycles, compositions containing the peptoid-peptide macrocycles, and methods of using the peptoid-peptide macrocycles.
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2.发明申请ANTIBODIES THAT RECOGNIZE AND BIND PHOSPHORYLATED HUMAN ANDROGEN RECEPTOR AND METHODS OF USING SAME 审中-公开识别和结合磷酸化人类雄激素受体的抗体及其使用方法
公开(公告)号：WO2005017179A2
公开(公告)日：2005-02-24
申请号：PCT/US2004/015849
申请日：2004-05-20
Applicant: NEW YORK UNIVERSITY , LOGAN, Susan , GARABEDIAN, Michael, J.
Inventor： LOGAN, Susan , GARABEDIAN, Michael, J.
IPC: C12Q
CPC classification number: C07K16/2869 , C07K2317/34
Abstract: A phosphorylation site-specific antibody that recognizes phosphorylated serine (213) within the N-terminus of the androgen receptor was obtained which can be used in methods for determining the presence of activated androgen receptors in cells or tissue of human androgen responsive tissue and for screening for an androgen inhibitor or an androgen agonist
Abstract translation: 获得识别雄激素受体的N端内的磷酸化丝氨酸（213）的磷酸化位点特异性抗体，其可用于确定细胞或组织中激活的雄激素受体的存在的方法中 的人类雄激素反应性组织和筛查雄激素抑制剂或雄激素激动剂
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