公开(公告)号：WO2013124492A1

公开(公告)日：2013-08-29

申请号：PCT/EP2013/053747

申请日：2013-02-25

Applicant: OPTINOSE AS

Inventor： DJUPESLAND, Per Gisle ,  GORDON, Joseph ,  LECLERC, Michael ,  MAHMOUD, Ramy A ,  SIWINSKI, Shane

IPC: A61M15/08

CPC classification number: A61M15/08 ,  A61M15/0021 ,  A61M15/0098 ,  A61M2202/064 ,  A61M2205/0216 ,  A61M2210/0618 ,  A61M2210/0625

Abstract: A nasal delivery device for delivering substance to a nasal cavity of a subject compries: a housing (15); a nosepiece (17) for fitting to a nasal cavity of the subject; a mouthpiece (19) through which the subject in use exhales; and a flexible coupling (20) which couples the mouthpiece to the housing, wherein the flexible coupling provides for asymmetric translation of the mouthpiece relative to the nosepiece.

Abstract translation: 用于将物质输送到受试者的鼻腔的鼻输送装置：壳体（15）; 用于装配到受试者的鼻腔的鼻梁（17）; 用于呼气的受试者的喉舌（19）; 以及将所述接口件连接到所述壳体的柔性联接器（20），其中所述柔性联接件提供所述接口件相对于所述鼻梁的不对称平移。

公开(公告)号：WO2013124491A1

公开(公告)日：2013-08-29

申请号：PCT/EP2013/053746

申请日：2013-02-25

Applicant: OPTINOSE AS

Inventor： DJUPESLAND, Per Gisle ,  LECLERC, Michael ,  MAHMOUD, Ramy A ,  SIWINSKI, Shane ,  GORDON, Joseph ,  FISK, Justin

IPC: A61M15/08 ,  A61M15/00

CPC classification number: A61M15/08 ,  A61M15/0018 ,  A61M15/002 ,  A61M15/0021 ,  A61M15/009 ,  A61M15/0098 ,  A61M2210/0618

Abstract: A nasal delivery device for and method of delivering substance to a nasal airway of a subject, the delivery device comprising: a nosepiece (117) for fitting to a nasal cavity of a subject; a mouthpiece (119) into which the subject in use exhales; a delivery unit, which comprises an actuation part which is manually displaceable to actuate the delivery unit to deliver substance from the nosepiece; and a valve assembly (127) which is fluidly connected to the nosepiece and the mouthpiece, wherein the valve assembly comprises a body element (128) and a valve element (131) which is movably disposed to the body element between closed and open configurations by manual displacement of the actuation part of the delivery unit to provide for an air flow through the nosepiece simultaneously with delivery of substance.

Abstract translation: 一种用于将物质输送到受试者的鼻气道的鼻输送装置和方法，所述输送装置包括：鼻梁（117），用于装配到受试者的鼻腔; 使用者呼气的受试者（119）; 输送单元，其包括可手动地移动以致动输送单元以从物镜输送物质的致动部分; 以及阀组件（127），其流体地连接到所述喷嘴和所述接口管，其中所述阀组件包括主体元件（128）和阀元件（131），所述主体元件（128）和阀元件（131）通过 输送单元的致动部分的手动位移以提供与物质输送同时通过喷嘴的气流。