公开(公告)号：WO2018217104A1

公开(公告)日：2018-11-29

申请号：PCT/NZ2018/050073

申请日：2018-05-24

Applicant: OTAGO INNOVATION LIMITED

Inventor： MELEDANDRI, Carla Joy ,  COTTON, Gemma Claire ,  SCHWASS, Donald Royden

IPC: A61K6/083 ,  A61L24/12 ,  A61K33/38 ,  A61P31/04

CPC classification number: A61P31/04 ,  A61K6/046 ,  A61K6/0835 ,  A61L24/0089 ,  A61L24/12 ,  C08L33/10 ,  C08L33/08

Abstract: The present invention relates to a glass ionomer cement comprising: (i) nanoparticles of metallic silver (Ag); (ii) a polymer comprising carboxylate groups; (iii) bridging molecules comprising at least one group capable of binding to Ag; (iv) metal ions; and (v) aluminosilicate particles; wherein at least some of the aluminosilicate particles are bound to the polymer through a linking structure of the following general formula: polymer-M-B-Ag-B-M-aluminosilicate where M is a metal ion, B is a bridging molecule, and Ag is a silver nanoparticle. The invention further relates to a dental preparation product comprising a liquid phase and a solid phase separated from each other, wherein the liquid phase comprises: (i) nanoparticles of metallic silver; (ii) a polymer comprising carboxylate groups; and (iii) bridging molecules comprising at least one group capable of binding to Ag; and wherein the solid phase comprises particles of an aluminosilicate compound.

公开(公告)号：WO2014116121A9

公开(公告)日：2014-07-31

申请号：PCT/NZ2014/000006

申请日：2014-01-24

Applicant: OTAGO INNOVATION LIMITED

Inventor： MELEDANDRI, Carla Joy ,  SCHWASS, Donald Royden

IPC: A61K6/00 ,  A61K33/38 ,  A61P31/04

Abstract: An assembly of micelle aggregates, wherein each aggregate comprises micelles of an anionic surfactant and nano-sized particles of metallic silver. A product comprising such assemblies for use in treating or preventing bacterial infections.