公开(公告)号：WO2020079703A1

公开(公告)日：2020-04-23

申请号：PCT/IN2019/050063

申请日：2019-01-28

Applicant: PAYELI, Sravan Kumar

Inventor： PAYELI, Sravan Kumar ,  ADABALA, Kalyan ,  SULTANA, Aamena ,  MOCHARLA, Pavani Srividya

IPC: G06T7/00 ,  G06T7/254 ,  G06T7/62

Abstract: Examples of monitoring of follicular fluid flow using image processing are described herein. Image frames pertaining to a pre-defined target area defined for a collection tube during an ovum pick-up (OPU) step of an in-vitro fertilization (IVF) procedure may be obtained in real-time. The target area corresponds to a region indicating entry of a follicular fluid into the collection tube. Thereafter, the image frames may be processed to detect occurrence of a flow of the follicular fluid as well as presence of blood in the follicular fluid. Accordingly, a first alert signal indicating detection of occurrence of flow of the follicular fluid and a second alert signal indicating presence of blood in the follicular fluid, may be generated to notify a medical practitioner.

公开(公告)号：WO2020188598A1

公开(公告)日：2020-09-24

申请号：PCT/IN2020/050256

申请日：2020-03-19

Applicant: PAYELI, Sravan Kumar

Inventor： PAYELI, Sravan Kumar

IPC: B65D81/18 ,  F25D3/10 ,  A01N1/02

Abstract: Gametes are stored for future use/ transport between laboratories. Cryopreservation techniques are employed for the efficient storage of gametes. A cryopreservation box (100) open from the top for holding female gametes collection tubes is disclosed. The cryopreservation box (100) comprises at least one slot (112) to hold at least one female gametes carrier device, an inlet chamber (122) at one end of the first wall (104), wherein the inlet chamber (122) has a base sloping downwards towards the base surface (102), a downward sloping surface (114 to flow liquid nitrogen from the inlet chamber (122) to a first liquid nitrogen holding chamber (132) formed by the base surface (102), the first wall (104), the downward sloping surface (114), and a second wall (106) of the cryopreservation box (100), the second wall (106) being adjacent to the first wall (104); and a reservoir (124) at another end of the first wall (104).

公开(公告)号：WO2020110137A1

公开(公告)日：2020-06-04

申请号：PCT/IN2019/050491

申请日：2019-07-02

Applicant: PAYELI, Sravan Kumar

Inventor： PAYELI, Sravan Kumar ,  MOCHARLA, Pavani Srividya

IPC: A61B17/435 ,  A61B17/42 ,  A61B17/425 ,  A61B17/43

Abstract: The present subject matter discloses a device and system of aspirating follicular fluid. In an example, an ovum pick up (OPU) device for aspirating follicular fluid includes a needle having a first end and a second end, opposite to the first end. The first end of the needle is to pierce through an ovarian follicle to aspirate the follicular fluid from the ovarian follicle by a suction force. The OPU device includes a connector having a channel to receive the second end of the needle. The OPU device further includes an elastic tube connected to the connector. The second end of the needle passes through the channel and inside the elastic tube. The elastic tube is compressible, while locating the ovarian follicle and piercing the needle through the ovarian follicle, to regulate the suction force during aspiration of the follicular fluid between two follicles.

公开(公告)号：WO2020188600A1

公开(公告)日：2020-09-24

申请号：PCT/IN2020/050259

申请日：2020-03-19

Applicant: PAYELI, Sravan Kumar

Inventor： PAYELI, Sravan Kumar

IPC: C12M3/10 ,  C12N5/00 ,  G01N33/48

Abstract: In an example, a sperm selection apparatus (200), comprises a first sperm pick-up chamber (208) formed on a base surface (204) and connected to a sperm loading chamber (206) via a first path (P1), a second sperm pick-up chamber (210) formed on the base surface (204) and connected to the sperm loading chamber via a second path (P2) for sperms to flow from the sperm loading chamber (206) to the second sperm pick-up chamber (210); and one or more barriers (300) are formed in at least one of the first path (P1) or second path (P2), wherein the one or more barriers (300) replicate physical barriers of cervix for selection of sperms.

公开(公告)号：WO2020183482A1

公开(公告)日：2020-09-17

申请号：PCT/IN2019/050487

申请日：2019-06-28

Applicant: PAYELI, Sravan Kumar

Inventor： PAYELI, Sravan Kumar ,  MOCHARLA, Pavani Srividya

IPC: C12M3/00 ,  C12M1/00 ,  C12M1/32

Abstract: Examples of an ovum culture tray are described. In an example, an ovum culture tray (100) comprises a base surface (102), a tray wall (104) forming a boundary of the base surface (102), and a well (106) on the base surface (102). The well (106) has a circular base (108) and four walls (110) surrounding the circular base (108). The well has a square or rectangular open end opposite to the circular base (108). A wall, from amongst the four walls, is inclined at an obtuse angle with respect to a plane of the circular base (108). The well walls are in contact with surrounding material or substance that transfer heat into the well (106).

公开(公告)号：WO2021014462A1

公开(公告)日：2021-01-28

申请号：PCT/IN2020/050612

申请日：2020-07-17

Applicant: PAYELI, Sravan Kumar

Inventor： PAYELI, Sravan Kumar ,  MOCHARLA, Pavani Srividya

IPC: A61M1/00 ,  A61B17/435 ,  A61M5/315 ,  A61M39/22

Abstract: An aspiration system (100) is provided with a piston unit (102) having a base member (104) and a plurality of arms (106) extending outwards from the base member. The plurality of arms is in a same plane and includes a first arm (106a), a second arm (106b), and a third arm (106c). A cap (108) affixed to a free end of the third arm of the piston unit. A hollow tube (110) having an open end is disposed over the third arm to form a hermetic seal with the cap. A nozzle (114) is positioned opposite to the open end and connectable to a fluid collection tube (116). The piston unit is acted upon by gravity to create a negative pressure inside the hollow tube to cause the aspiration of the biological fluids.

公开(公告)号：WO2021014461A1

公开(公告)日：2021-01-28

申请号：PCT/IN2020/050610

申请日：2020-07-16

Applicant: PAYELI, Sravan Kumar

Inventor： PAYELI, Sravan Kumar ,  MOCHARLA, Pavani Srividya

IPC: C12M3/00 ,  A61B17/43 ,  C12M1/42 ,  C12M1/36

Abstract: The present subject matter relates to automated intracytoplasmic sperm injection system (100, 200). System (100, 200) includes first and second syringes (116, 130, 204, 206) connected to first and second micropipettes 5 (112, 126, 228, 230), respectively, processing unit (208) to store first, second, third, and fourth pressure values, and actuator (210) coupled to processing unit (208), first syringe (116, 204), and second syringe (130, 206), to operate second syringe (130, 206) based first pressure value to collect sperm, first syringe (116, 204) based on second pressure value to 10 hold oocyte, second micropipette (126, 230) to penetrate first oocyte layer, operate second syringe (130, 206) based on third pressure value to puncture second oocyte layer, and operate second syringe (130, 206) based on fourth pressure value to deposit sperm into oocyte. The pressure values are based on machine learning framework.

公开(公告)号：WO2020174481A1

公开(公告)日：2020-09-03

申请号：PCT/IN2019/050149

申请日：2019-02-25

Applicant: PAYELI, Sravan Kumar

Inventor： PAYELI, Sravan Kumar ,  MOCHARLA, Pavani Srividya

IPC: A01N1/02 ,  A61D19/02

Abstract: Examples of a cryopreservation device (200, 300) for storing reproductive biological material are described herein. The device (200, 300) includes a vitrification straw (202, 302) having an elongated member (208, 306) with a planar base and a triangular cross-section. The vitrification straw (202, 302) further includes a tip member (208, 308) extending away from one end of the elongated member (208, 306). At least a portion of the tip member (208, 308) defines a cavity (212) to receive the biological material. Further, the cryopreservation device includes a sheath (204, 304, 402) for being disposed over the tip member (208, 308) of the vitrification straw (202, 302).