公开(公告)号：WO2009010379A3

公开(公告)日：2009-10-22

申请号：PCT/EP2008058232

申请日：2008-06-27

Applicant: PROXEON BIOSYSTEMS AS ,  VORM OLE ,  GRAF THOMAS

Inventor： VORM OLE ,  GRAF THOMAS

IPC: H01J49/16

CPC classification number: H01J49/16 ,  H01J49/167

Abstract: The present invention provides a novel nanospray emitter that includes a fluid inlet, an outlet orifice, and a passage for fluid: communication between the fluid inlet and outlet orifice. In one aspect of this embodiment, the passage facilitating fluid communication between the inlet and outlet elements is comprised of an outer capillary of a rigid material, such as nickel, that houses an inner capillary made from a highly conductive and inert material, such as gold; alternatively the inner material may constitute an inner coating of the outer capillary.

Abstract translation: 本发明提供了一种新颖的纳米喷雾发射器，其包括流体入口，出口孔和用于流体的通道：流体入口和出口孔之间的连通。 在该实施例的一个方面，促进入口和出口元件之间的流体连通的通道包括刚性材料（例如镍）的外部毛细管，其容纳由高导电性和惰性材料制成的内部毛细管，例如金 ; 或者，内部材料可以构成外部毛细管的内部涂层。

公开(公告)号：WO2009098125A8

公开(公告)日：2009-10-01

申请号：PCT/EP2009050697

申请日：2009-01-22

Applicant: PROXEON BIOSYSTEMS AS ,  VORM OLE

Inventor： VORM OLE

IPC: B01D15/16 ,  G01N30/32 ,  G01N30/36

CPC classification number: G01N30/32 ,  B01D15/163 ,  G01N30/36 ,  G01N2030/324 ,  G01N2030/326

Abstract: A method for controlling the flow of liquid in a high performance liquid chromatography apparatus. The method includes operating a pump, measuring the liquid pressure downstream of the pump, measuring the liquid flow rate downstream of the pump, and controlling the operation of the pump. In the method, it is automatically determined whether the pump is controlled to achieve a desired pressure or controlled to achieve a desired flow rate. Fuzzy logic can be applied in the method to determine the switch between the control modes.

Abstract translation: 一种控制高效液相色谱仪中液体流动的方法。 该方法包括操作泵，测量泵下游的液体压力，测量泵下游的液体流速，并控制泵的运行。 在该方法中，自动确定泵是否被控制以实现期望的压力或被控制以实现期望的流量。 模糊逻辑可以用于确定控制模式之间切换的方法。

公开(公告)号：WO0190194A3

公开(公告)日：2002-06-20

申请号：PCT/EP0105943

申请日：2001-05-23

Applicant: ROCHE DIAGNOSTICS GMBH ,  HOFFMANN LA ROCHE ,  HOESEL WOLFGANG ,  PETER JOCHEN ,  VORM OLE ,  KROGH THOMAS N

Inventor： HOESEL WOLFGANG ,  PETER JOCHEN ,  VORM OLE ,  KROGH THOMAS N

IPC: G01N33/577 ,  C07K5/10 ,  C07K7/06 ,  C07K16/18 ,  C07K16/40 ,  C12N15/02 ,  C12P21/08 ,  G01N33/574 ,  C07K16/30 ,  C07K14/705

CPC classification number: G01N33/57434 ,  C07K16/40 ,  G01N2333/8132

Abstract: The invention relates to antibodies against particular forms of enzymatically-inactive precursors of the prostate specific antigen (PSA), the production and use thereof in immunoassays for the determination of the [-5,-6,-7]-proPSA and application of the measured values from said assays, for an improved diagnosis in the field of prostate carcinomas.

Abstract translation: 本发明涉及针对前列腺特异性抗原的无酶活性的前体的特定形式（PSA），它们的制备，它们在免疫测定使用用于测定抗体[-5，-6，-7] proPSA，并从这些测定中使用的测定值的 在前列腺癌领域改进的诊断。