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公开(公告)号:WO2021146346A1
公开(公告)日:2021-07-22
申请号:PCT/US2021/013320
申请日:2021-01-13
IPC分类号: H01S3/00 , H01S3/102 , H01S3/11 , H01S3/081 , H01S3/08 , G01N21/64 , H01S3/02 , H01S3/16 , H01S3/04 , H01S3/06 , H01S3/13 , G01N2021/6421 , G01N21/6402 , G01N21/6408 , G01N21/6454 , G01N21/648 , G01N2201/0697 , H01S3/0085 , H01S3/025 , H01S3/027 , H01S3/0405 , H01S3/0623 , H01S3/08045 , H01S3/0805 , H01S3/08059 , H01S3/08072 , H01S3/0813 , H01S3/10038 , H01S3/1022 , H01S3/1024 , H01S3/1068 , H01S3/107 , H01S3/1115 , H01S3/1118 , H01S3/13017 , H01S3/1305 , H01S3/1611 , H01S3/1673
摘要: Systems and methods are described for producing an amplitude-modulated laser pulse train. The laser pulse train can be used to cause fluorescence in materials at which the pulse trains are directed. The parameters of the laser pulse train are selected to increase fluorescence relative to a constant-amplitude laser pulse train. The amplitude-modulated laser pulse trains produced using the teachings of this invention can be used to enable detection of specific molecules in applications such as gene or protein sequencing.