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公开(公告)号：WO2019236783A1
公开(公告)日：2019-12-12
申请号：PCT/US2019/035693
申请日：2019-06-06
Applicant: REGENERON PHARMACEUTICALS, INC.
Inventor： GONZAGA-JAUREGUI, Claudia , SIAO, Chia-Jen , NISTALA, Harikiran , NANNURU, Kalyan C.
Abstract: This disclosure relates to a rodent model of Steel Syndrome. Disclosed herein are genetically modified rodent animals that carry a mutation in an endogenous rodent Col27al gene, equivalent to a mutation in humans causing Steel Syndrome.
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