公开(公告)号：WO2015197830A1

公开(公告)日：2015-12-30

申请号：PCT/EP2015/064547

申请日：2015-06-26

Applicant: RESEARCH CENTER PHARMACEUTICAL ENGINEERING GMBH

Inventor： TREFFER, Daniel ,  GRUBBAUER, Johann ,  KOSCHER, Gerold ,  KLEIN, Thomas ,  KHINAST, Johannes

IPC: B29C33/68 ,  B29C43/14 ,  B29C43/56 ,  B29K105/00

CPC classification number: B29C43/14 ,  B29C33/68 ,  B29C43/027 ,  B29C43/361 ,  B29C43/52 ,  B29C43/56 ,  B29C43/58 ,  B29C2043/029 ,  B29C2043/3233 ,  B29C2043/3615 ,  B29C2043/563 ,  B29C2043/5816 ,  B29K2101/12 ,  B29K2105/0035 ,  B29L2031/40 ,  B29L2031/753

Abstract: There is provided an apparatus for molding a thermoplastic material into a homogenous sample body having a predetermined shape, the apparatus comprising: (a) a main body (110) comprising a first opening (112), a second opening and a hollow bore (116) connecting the first opening (112) with the second opening, the hollow bore (116) being adapted to receive a separation foil shaped to cover at least a part of the hollow bore surface; (b) a piston (120) adapted to fit moveably into the hollow bore (116) containing the separation foil; (c) a base plate (130) comprising a protrusion, wherein the base plate (130) is adapted to be inserted into the first opening (112) in such a manner that the protrusion extends into a part of the hollow bore (116) containing the separation foil, and wherein the base plate (130) is adapted to transfer heat from a heating unit to a thermoplastic material (150) resting on the protrusion (132); (d) a vacuum connector (142) adapted to be connected to a vacuum source; (e) a lid (140) adapted to fit moveably into the second opening and adapted to apply a force to the piston (120) when the vacuum connector (142) is connected to the vacuum source such that the piston (120) applies a compressing force to the thermoplastic material (150) resting on the protrusion. There are further provided a method and a system for molding a thermoplastic material into a homogenous sample body having a predetermined shape.

Abstract translation: 提供了一种用于将热塑性材料模制成具有预定形状的均匀样品体的装置，该装置包括：（a）主体（110），包括第一开口（112），第二开口和中空孔 ）将所述第一开口（112）与所述第二开口连接，所述中空孔（116）适于容纳形成为覆盖所述中空孔表面的至少一部分的分离箔; （b）适于可移动地装配到容纳分离箔的中空孔（116）中的活塞（120）; （c）包括突起的基板（130），其中所述基板（130）适于以突出部延伸到所述中空孔（116）的一部分中的方式插入所述第一开口（112） ，其中所述基板（130）适于将热量从加热单元传递到搁置在所述突起（132）上的热塑性材料（150）; （d）适于连接到真空源的真空连接器（142）; （e）适于可动地装配到所述第二开口中并且当所述真空连接器（142）连接到所述真空源时将力施加到所述活塞（120）的盖（140），使得所述活塞（120）施加 压缩到搁置在突起上的热塑性材料（150）的力。 还提供了一种用于将热塑性材料模制成具有预定形状的均匀样品体的方法和系统。

公开(公告)号：WO2015022408A1

公开(公告)日：2015-02-19

申请号：PCT/EP2014/067449

申请日：2014-08-14

Applicant: TECHNISCHE UNIVERSITÄT GRAZ ,  RESEARCH CENTER PHARMACEUTICAL ENGINEERING GMBH

Inventor： TREFFER, Daniel ,  KHINAST, Johannes ,  GRUBBAUER, Johann ,  EITZLMAYR, Andreas ,  KOSCHER, Gerold ,  KLEIN, Thomas

IPC: B29C47/00 ,  B29C47/30 ,  B29C47/86 ,  B29B9/06 ,  B29C47/08 ,  B29C47/40 ,  B29C47/82

CPC classification number: B29B9/06 ,  B29B9/065 ,  B29C47/0011 ,  B29C47/0014 ,  B29C47/0066 ,  B29C47/0893 ,  B29C47/30 ,  B29C47/402 ,  B29C47/822 ,  B29C47/862 ,  B29C47/864 ,  B29C2793/0027 ,  B29C2793/009 ,  B29C2947/92704 ,  B29C2947/92904 ,  B29K2995/0013 ,  B29K2995/0015 ,  Y02P70/263

Abstract: An apparatus (100) for manufacturing particles, wherein the apparatus (100) comprises a supply unit (102) adapted for supplying a viscous raw material, a perforated body (104) having a plurality of perforations (106) and arranged to receive the viscous raw material from the supply unit (102) to flow through the plurality of perforations (106), and a cutter (108) arranged so that the viscous raw material flowing out of the plurality of perforations (106) is cut into the particles by the cutter (108), wherein the apparatus (100) is configured so that, during manufacturing the particles, a temperature of at least a portion of the perforated body (104) is lower than a temperature of the viscous raw material flowing through the plurality of perforations (106), wherein the perforated body (104) and the cutter (108) are arranged relative to one another such that the cutter (108) is cooled by thermal exchange with the perforated body (104) during operation of the apparatus (100).

Abstract translation: 一种用于制造颗粒的设备（100），其中所述设备（100）包括适于供应粘性原料的供应单元（102），具有多个穿孔（106）的多孔体（104），并布置成接收粘性 来自供应单元（102）的原料流过多个穿孔（106），以及切割器（108），其布置成使得从多个穿孔（106）流出的粘性原料通过 切割器（108），其中所述设备（100）被构造成使得在制造所述颗粒期间，所述穿孔体（104）的至少一部分的温度低于流过所述多个 穿孔（106），其中穿孔体（104）和切割器（108）相对于彼此布置，使得在设备（100）的操作期间刀具（108）通过与多孔体（104）的热交换而被冷却 ）。