公开(公告)号：WO2014152918A1

公开(公告)日：2014-09-25

申请号：PCT/US2014/028233

申请日：2014-03-14

Applicant: SAFEWHITE LLC

Inventor： BRODY, Richard Simon ,  ZUPANCIC, Thomas Joel ,  HOEFER, Nicole ,  SANDBHOR, Uday B.

IPC: A61Q11/00

CPC classification number: A61K8/64 ,  A61K8/24 ,  A61K8/25 ,  A61K8/27 ,  A61K8/29 ,  A61K8/44 ,  A61K8/8152 ,  A61K2800/28 ,  A61K2800/413 ,  A61K2800/42 ,  A61K2800/592 ,  A61Q11/00

Abstract: This document provides methods and materials for delivering compounds to teeth and methods and materials for providing teeth with a whiter appearance. For example, methods and materials are provided for contacting teeth with one or more adhesive molecules (e.g., mussel adhesive polypeptides or polymer containing a plurality of 3,4-dihydroxyphenyl-L-alanine residues) in combination with one or more fluorescence emitting polypeptides (e.g., a blue fluorescent protein (BFP)) and/or whitening particles to provide the teeth with a whiter appearance.

Abstract translation: 本文件提供了将化合物递送到牙齿的方法和材料以及用于提供更白色外观的牙齿的方法和材料。 例如，提供方法和材料用于使一个或多个粘附分子（例如，贻贝粘合剂多肽或含有多个3,4-二羟基苯基-L-丙氨酸残基的聚合物）与一种或多种荧光发射多肽 例如蓝色荧光蛋白（BFP））和/或增白颗粒以使牙齿具有更白的外观。