公开(公告)号：WO2017001617A1

公开(公告)日：2017-01-05

申请号：PCT/EP2016/065415

申请日：2016-06-30

Applicant: SEQUESSOME TECHNOLOGY HOLDINGS LIMITED

Inventor： HENRY, William ,  GARRAWAY, Richard Wolf

IPC: A61K9/00 ,  A61K9/10 ,  A61K9/127 ,  A61K47/24 ,  A61K47/26 ,  A61K31/155 ,  A61P17/00 ,  A61K8/43

CPC classification number: A61K9/0014 ,  A61K8/43 ,  A61K9/10 ,  A61K9/1272 ,  A61K31/155 ,  A61K31/165 ,  A61K31/355 ,  A61K31/522 ,  A61K31/60 ,  A61K31/618 ,  A61K31/7008 ,  A61K31/737 ,  A61K47/24 ,  A61K47/26 ,  A61K2300/00

Abstract: The present invention relates to a formulation comprising blends of formulations (or colloidal dispersions) and its topical application. The formulation comprises at least two different types of colloidal dispersion comprising deformable colloidal particles, wherein the deformable colloidal particles comprise a non-ionic surfactant and/or a phospholipid. The deformable colloidal particles of the invention may comprise an agent of interest (AOI) or may be free of an AOI. The formulation may comprise an AOI that is not associated with the deformable colloidal particles. The present invention also includes kits comprising the formulation of the present invention and the use of the formulation in medicine, skin care and cosmetics.

Abstract translation: 本发明涉及包含制剂（或胶体分散体）和其局部应用的共混物的制剂。 该制剂包含至少两种不同类型的包含可变形胶体颗粒的胶体分散体，其中可变形胶体颗粒包含非离子表面活性剂和/或磷脂。 本发明的可变形胶体颗粒可以包含感兴趣的试剂（AOI）或可以不含AOI。 制剂可以包含与可变形胶体颗粒不相关的AOI。 本发明还包括包含本发明的制剂和该制剂在医药，护肤和化妆品中的用途的试剂盒。

公开(公告)号：WO2016156470A1

公开(公告)日：2016-10-06

申请号：PCT/EP2016/057027

申请日：2016-03-31

Applicant: SEQUESSOME TECHNOLOGY HOLDINGS LIMITED

Inventor： GARRAWAY, Richard Wolf ,  EARL, Michael James ,  HENRY, William

IPC: A61K31/685 ,  A61K9/00 ,  A61K45/06 ,  A61K47/26 ,  A61K9/127 ,  A61K31/739 ,  A61P21/00 ,  A61P19/04

CPC classification number: A61K31/739 ,  A61K9/0014 ,  A61K9/10 ,  A61K9/107 ,  A61K31/685 ,  A61K47/24 ,  A61K47/26

Abstract: The present invention relates to formulations containing ultra-deformable drug-free particles and their use in treating soft-tissue soreness, such as delayed onset muscle soreness (DOMS) and exercise-induced muscle soreness. The formulations of the invention comprise a non-ionic surfactant and/or a phospholipid and are free of any pharmaceutically active agent.

Abstract translation: 本发明涉及含有超可变形药物颗粒的制剂及其在治疗软组织酸痛中的应用，例如延迟发作肌肉酸痛（DOMS）和运动性肌肉酸痛。 本发明的制剂包含非离子表面活性剂和/或磷脂，并且不含任何药物活性剂。

公开(公告)号：WO2017001625A1

公开(公告)日：2017-01-05

申请号：PCT/EP2016/065425

申请日：2016-06-30

Applicant: SEQUESSOME TECHNOLOGY HOLDINGS LIMITED

Inventor： GARRAWAY, Richard Wolf ,  HENRY, William

IPC: A61K9/00 ,  A61K8/43 ,  A61K9/10 ,  A61K31/155 ,  A61P17/00 ,  A61K47/26 ,  A61K47/24 ,  A61K9/127

CPC classification number: A61K9/0014 ,  A61K8/43 ,  A61K9/10 ,  A61K9/1272 ,  A61K31/155 ,  A61K31/165 ,  A61K31/355 ,  A61K31/522 ,  A61K31/60 ,  A61K31/618 ,  A61K31/7008 ,  A61K31/737 ,  A61K47/24 ,  A61K47/26 ,  A61K2300/00

Abstract: The present invention relates to compositions comprising a colloidal dispersion and an Agent of Interest ("AOI"), wherein the colloidal dispersion comprises deformable colloidal particles and wherein the AOI is not associated with the deformable colloidal particles. The present invention also provides kits and transdermal drug release devices comprising the compositions of the present invention, and the use of these compositions in medicine, skin care and cosmetics.

Abstract translation: 本发明涉及包含胶体分散体和感兴趣剂（“AOI”）的组合物，其中胶体分散体包含可变形的胶体颗粒，并且其中AOI与可变形胶体颗粒不相关。 本发明还提供了包含本发明组合物的试剂盒和透皮药物释放装置，以及这些组合物在医药，护肤和化妆品中的用途。