公开(公告)号：WO2014074806A1

公开(公告)日：2014-05-15

申请号：PCT/US2013/069123

申请日：2013-11-08

Applicant: SMITH & NEPHEW, INC--

Inventor： CARVELL, Kelsey, Jean ,  CHENG, Ruth ,  SMITH, Graham ,  BURDON, Drew ,  TORRIE, Paul, Alexander

IPC: A61B17/04 ,  A61F2/28 ,  A61K9/00 ,  A61K35/12 ,  A61K38/00 ,  A61K38/18 ,  A61L27/26

CPC classification number: A61B17/56 ,  A61B17/1604 ,  A61B17/1606 ,  A61B2017/564 ,  A61K31/19 ,  A61K36/752 ,  A61K38/4873 ,  A61M1/0023 ,  A61M1/0058 ,  A61M2210/02 ,  A61M2210/08

Abstract: The methods and devices disclosed herein are effective in the promoting the reattachment of delaminated cartilage to bone. The methods (and related devices) are effective in the removal of the acellular layer of the delaminated cartilage or effective in the indentation of the acellular layer of the delaminated cartilage thereby exposing the underlying chondrocyte cells and thereby allowing the promotion of the reattachment of the delaminated cartilage.

Abstract translation: 本文公开的方法和装置在促进分层软骨重新附着到骨上是有效的。 方法（和相关装置）在去除分层软骨的无细胞层或有效地分层软骨的无细胞层的压痕中有效，从而暴露下面的软骨细胞，从而允许促进分层的软骨的再附着 软骨。

公开(公告)号：WO2014074804A2

公开(公告)日：2014-05-15

申请号：PCT/US2013/069118

申请日：2013-11-08

Applicant: SMITH & NEPHEW, INC.

Inventor： CARVELL, Kelsey, Jean ,  CHENG, Ruth ,  SMITH, Graham ,  BURDON, Drew

IPC: A61L24/00 ,  A61L24/10

CPC classification number: A61L24/0015 ,  A61K9/0024 ,  A61K47/42 ,  A61L24/106 ,  A61L27/225 ,  A61L27/54 ,  A61L2300/254 ,  A61L2300/426 ,  A61L2300/43 ,  A61L2300/63 ,  A61L2300/802 ,  A61L2430/06

Abstract: The methods and compositions disclosed herein are effective in the promoting the reattachment of delaminated cartilage to bone. The methods (and related compositions) comprise the removal of the acellular layer of the delaminated cartilage thereby exposing the underlying chondrocyte cells thereby allowing the promotion of the reattachment of the delaminated cartilage.

Abstract translation: 本文公开的方法和组合物有效促进分层的软骨重新附着于骨骼。 方法（和相关组合物）包括去除分层软骨的无细胞层，从而暴露下面的软骨细胞，从而允许促进分层软骨的重新附着。