中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

24 records (took 0.012 seconds)

    PROCESS FOR THE MANUFACTURE OF FLUOROMETHOXYMALONIC ACID DERIVATIVES
    3.
    发明申请
    PROCESS FOR THE MANUFACTURE OF FLUOROMETHOXYMALONIC ACID DERIVATIVES 审中-公开
    氟代甲醛酸衍生物的制备方法

    公开(公告)号：WO2012107438A1

    公开(公告)日：2012-08-16

    申请号：PCT/EP2012/052035

    申请日：2012-02-07

    Applicant: SOLVAY SA ,  BRAUN, Max Josef ,  CLAASSEN, Uta

    Inventor： BRAUN, Max Josef ,  CLAASSEN, Uta

    IPC: C07C67/307 ,  C07C69/708 ,  C07C41/22

    CPC classification number: C07C67/287 ,  C07C41/01 ,  C07C67/307 ,  C07C69/708

    Abstract: Process for the manufacture of a compound of formula R 1 OOC-CH(OCH 2 F)-COOR 2 (I) or R 3 HNOC-CH(OCH 2 F)-CONHR 4 (II) wherein R 1 , R 2 , R 3 , R 4 are equal or different from each other and are independently selected from H; an alkyl group having from 1 to 10 carbon atoms which is optionally substituted by at least one halogen atom; an aralkyl group; or an aryl group, comprising reacting a compound of formula R 1 OOC-CH(OCH 2 X)-COOR 2 (III) or R 3 HNOC-CH(OCH 2 X)-CONHR 4 (IV) wherein X is a leaving group that can be substituted by nucleophilic substitution, and wherein R 1 , R 2 , R 3 , R 4 have the same meaning as above, with at least one source of nucleophilic fluorine.

    Abstract translation: 制备式R1OOC-CH（OCH2F）-COOR2（I）或R3HNOC-CH（OCH2F）-CONHR4（Ⅱ）化合物的方法，其中R 1，R 2，R 3，R 4彼此相同或不同，并且独立地 选自H; 任选被至少一个卤素原子取代的具有1至10个碳原子的烷基; 芳烷基; 包括使式R 1 OOC-CH（OCH 2 X）-COOR 2（III）或R 3 HNOC-CH（OCH 2 X）-CONHR 4（IV）的化合物与其中X是可被亲核取代取代的离去基团反应，其中 R1，R2，R3，R4具有与上述相同的含义，至少有一个亲核氟源。

    FLUORINATION PROCESS
    6.
    发明申请
    FLUORINATION PROCESS 审中-公开
    荧光法

    公开(公告)号：WO2015000935A1

    公开(公告)日：2015-01-08

    申请号：PCT/EP2014/064021

    申请日：2014-07-02

    Applicant: SOLVAY SA

    Inventor： JAUNZEMS, Janis ,  CLAASSEN, Uta ,  BRAUN, Max Josef

    IPC: C07C201/12

    CPC classification number: C07C201/12 ,  C07C205/43

    Abstract: It has been found that a compound of formula (I) R-CF 2 -O-Ar, wherein R is a fluorinated alkyl group or an optionally substituted aromatic or heteroaromatic group and Ar is an optionally substituted aromatic or heteroaromatic group, can be produced by a process comprising a step of reacting a compound of formula (II) R-C(O)-O-Ar wherein R and Ar are as defined above with a fluorination agent at a temperature of below +100°C.

    Abstract translation: 已经发现，式（I）R-CF 2 -O-Ar的化合物，其中R是氟化烷基或任选取代的芳族或杂芳族基团，Ar是任选取代的芳族或杂芳族基团，可以通过 一种方法包括使式（II）RC（O）-O-Ar的化合物（其中R和Ar定义如上）与氟化剂在低于+ 100℃的温度下反应的步骤。

    ENVIRONMENTAL FRIENDLY PURIFICATION OF AN ORGANIC SOLUTION OF ETFBO
    8.
    发明申请
    ENVIRONMENTAL FRIENDLY PURIFICATION OF AN ORGANIC SOLUTION OF ETFBO 审中-公开
    ETFBO有机溶剂环境友好的净化

    公开(公告)号：WO2012085195A1

    公开(公告)日：2012-06-28

    申请号：PCT/EP2011/073776

    申请日：2011-12-22

    Applicant: SOLVAY SA ,  BRAUN, Max Josef

    Inventor： BRAUN, Max Josef

    IPC: C07C49/255 ,  C07C45/45 ,  C07C45/82

    CPC classification number: C07C45/455 ,  C07C45/82 ,  C07C49/255

    Abstract: A process for the purification of an alkenone ether having the general formula (I): CF3-C(O)-C(H)=C(H)-OR wherein R is a C1-C4-alkyl group; or a C1-C4-alkyl group which is substituted by at least 1 halogen atom, aryl, substituted aryl,which comprises (a) subjecting a first fraction comprising said alkenone ether, water and optionally organic impurities to a liquid/vapour separation operation and (b) recovering from said liquid/vapour separation operation a fraction F containing purified alkenone ether, having reduced water content compared to the first fraction.

    Abstract translation: 用于纯化具有通式（I）的烯酮醚的方法：CF 3 -C（O）-C（H）= C（H）-OR，其中R是C 1 -C 4 - 烷基; 或被至少1个卤素原子取代的C 1 -C 4烷基，芳基，取代的芳基，其包括（a）使包含所述烯酮酮的第一级分，水和任选的有机杂质进行液/气分离操作，以及 （b）从所述液体/蒸气分离操作中回收含有与第一级分相比含水量降低的纯化的烯酮醚的馏分F.

    PROCESS FOR THE MANUFACTURE OF 2-SUBSTITUTED-5-(1-METHYLTHIO)ALKYLPYRIDINES
    9.
    发明申请
    PROCESS FOR THE MANUFACTURE OF 2-SUBSTITUTED-5-(1-METHYLTHIO)ALKYLPYRIDINES 审中-公开
    制备2-取代-5-（1-甲硫基）烷基吡啶的方法

    公开(公告)号：WO2017198812A2

    公开(公告)日：2017-11-23

    申请号：PCT/EP2017/062091

    申请日：2017-05-19

    Applicant: SOLVAY SA

    Inventor： BRAUN, Max Josef

    IPC: C07D213/32

    CPC classification number: C07D213/50 ,  C07C221/00 ,  C07D213/32 ,  C07C225/14

    Abstract: Process for the manufacture of 2-substituted-5-(1-methylthio)alkylpyridines and a process for the manufacture of agriculturally or pharmaceutically active substances comprising the process for the manufacture of 2-substituted-5-(1- methylthio)alkylpyridines.

    Abstract translation: 制备2-取代-5-（1-甲硫基）烷基吡啶的方法以及制备农业或药物活性物质的方法，该方法包括制备2-取代-5- （1-甲硫基）烷基吡啶。

    PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES
    10.
    发明申请
    PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES 审中-公开
    制备吡唑-4-羧酸酰胺的方法

    公开(公告)号：WO2016016298A1

    公开(公告)日：2016-02-04

    申请号：PCT/EP2015/067367

    申请日：2015-07-29

    Applicant: SOLVAY SA

    Inventor： BRAUN, Max Josef

    IPC: C07D231/14

    CPC classification number: C07D231/14

    Abstract: The invention concerns a process for the manufacture of pyrazole-4-carboxamides, in particular, of 3-difluoromethyl-1-methyl- H-pyrazole-4-carboxamides which are useful as pharmaceuticals and agrochemicals. The carboxamides are prepared from the corresponding pyzole-4-carboxylic acid esters and appropriate amine in the presence of a Lewis acid comprising at least one halogen ligand. Alternatively, the reaction is performed in the presence of a Lewis acid comprising at least one halogen ligand and a base.

    Abstract translation: 本发明涉及制造吡唑-4-甲酰胺的方法，特别是可用作药物和农用化学品的3-二氟甲基-1-甲基-1H-吡唑-4-甲酰胺。 羧酰胺由相应的吡唑-4-羧酸酯和适当的胺在含有至少一种卤素配体的路易斯酸存在下制备。 或者，反应在包含至少一个卤素配体和碱的路易斯酸存在下进行。

Patent Agency Ranking