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    ARTIFICIAL INTERVERTEBRAL DISC NUCLEUS
    3.
    发明申请
    ARTIFICIAL INTERVERTEBRAL DISC NUCLEUS 审中-公开
    人造椎间盘突出症

    公开(公告)号：WO2006039409A1

    公开(公告)日：2006-04-13

    申请号：PCT/US2005/035035

    申请日：2005-09-30

    Applicant: SYNECOR, LLC ,  SMITH, Jeffrey, A. ,  WILLIAMS, Michael, S.

    Inventor： SMITH, Jeffrey, A. ,  WILLIAMS, Michael, S.

    IPC: A61F2/44

    CPC classification number: A61F2/441 ,  A61B2017/00871 ,  A61F2002/30016 ,  A61F2002/30092 ,  A61F2002/30579 ,  A61F2002/30583 ,  A61F2002/30586 ,  A61F2002/444 ,  A61F2210/0014 ,  A61F2210/0085 ,  A61F2250/0019

    Abstract: Devices and methods for manufacturing devices for treating degenerated and/or traumatized intervertebral discs are disclosed. Artificial discs and components of discs may include an artificial nucleus and/or an artificial annulus and may be comprised of shape memory materials synthesized to achieve desired mechanical and physical properties. An artificial nucleus and/or annulus according to the invention may comprise a filler retention membrane that may be filled with a curable material for deployment. A filler retention membrane according to the invention may comprise one or more partitions to define one or more chambers and may comprise one or more valves for selectively permitting the flow of material within the nuclear region and annular region of the filler retention membrane.

    Abstract translation: 公开了用于制造用于治疗退化和/或创伤性椎间盘的装置的装置和方法。 人造盘和盘的组件可以包括人造核和/或人造环，并且可以由合成的形状记忆材料组成以实现期望的机械和物理性质。 根据本发明的人造核和/或环可以包括可填充有用于展开的可固化材料的填料保持膜。 根据本发明的填料保持膜可以包括一个或多个隔板以限定一个或多个室，并且可以包括一个或多个阀，用于选择性地允许在核区域内的填充物保持膜的核区域和环形区域中的材料流动。

    POLYMERIC ENDOPROSTHESES WITH ENHANCED STRENGTH AND FLEXIBILITY AND METHODS OF MANUFACTURE
    4.
    发明申请
    POLYMERIC ENDOPROSTHESES WITH ENHANCED STRENGTH AND FLEXIBILITY AND METHODS OF MANUFACTURE 审中-公开
    具有增强强度和柔韧性的聚合物内窥镜及制造方法

    公开(公告)号：WO2005081878A2

    公开(公告)日：2005-09-09

    申请号：PCT/US2005/005299

    申请日：2005-02-22

    Applicant: SYNECOR, LLC ,  WILLIAMS, Michael, S. ,  HOLBROOK, Kevin, D. ,  GLENN, Richard, A.

    Inventor： WILLIAMS, Michael, S. ,  HOLBROOK, Kevin, D. ,  GLENN, Richard, A.

    IPC: A61F2/02 ,  A61F2/82 ,  A61L29/12 ,  A61L29/18 ,  A61L31/12 ,  A61L31/18 ,  B32B1/08 ,  F16L11/00

    CPC classification number: A61F2/82 ,  A61L29/126 ,  A61L29/18 ,  A61L31/128 ,  A61L31/18

    Abstract: Improved polymeric endoprostheses and methods of manufacturing endoprostheses are disclosed herein. The endoprostheses may comprise one or more polymers wherein the polymer chains are substantially aligned circumferentially, and comprising increased radial strength and flexibility. An endoprosthesis according to the invention may comprise a smooth surface. Endoprostheses disclosed herein may be used in the treatment of strictures in lumens of the body. Alternatively, endoprostheses disclosed herein may be used as anchors to secure medical devices within lumens of the body. The endoprostheses disclosed herein may comprise one or more erodible polymer.

    Abstract translation: 本文公开了改进的聚合物内假体和生产内置假体的方法。 内置假体可以包含一种或多种聚合物，其中聚合物链基本上沿周向排列，并且包括增加的径向强度和挠性。 根据本发明的内置假体可以包括光滑表面。 本文公开的假体可用于治疗身体内腔的狭窄。 或者，本文公开的内置假体可以用作锚定件以将医疗装置固定在身体内腔内。 本文公开的内用假体可以包含一种或多种易侵蚀聚合物。

    UNIVERSAL PERCUTANEOUS SPINAL ACCESS SYSTEM
    5.
    发明申请
    UNIVERSAL PERCUTANEOUS SPINAL ACCESS SYSTEM 审中-公开
    通用PERCUTANEOUS脊髓访问系统

    公开(公告)号：WO2005081877A2

    公开(公告)日：2005-09-09

    申请号：PCT/US2005/005298

    申请日：2005-02-22

    Applicant: SYNECOR, LLC ,  STACK, Richard, S. ,  WILLIAMS, Michael, S.

    Inventor： STACK, Richard, S. ,  WILLIAMS, Michael, S.

    IPC: A61B17/16 ,  A61B17/32 ,  A61B17/88 ,  A61F2/44 ,  A61F2/46

    CPC classification number: A61B17/1631 ,  A61B17/1671 ,  A61B17/8805

    Abstract: A system for accessing the interior of a vertebral body or the intervertebral disc space above or below the vertebral body is disclosed. The system comprises a steerable cutting means for creating a path within or through the vertebral body to allow access for other devices to deliver a therapy, and may be housed within a flexible catheter shaft. The steerable cutting means may create a path to allow access to a device for removing tissue, and/or additional a devices for delivering a therapy, such as, for example, a filling material and/or a prosthesis. A method of accessing the interior of a vertebral body or the intervertebral disc space using the system, and a method of treatment of spinal disorders using the system are also disclosed.

    Abstract translation: 公开了一种用于进入椎体内部或椎体上方或下方的椎间盘空间的系统。 该系统包括可操纵的切割装置，用于在椎体内或穿过椎体以产生路径，以允许其他装置进入以递送治疗，并且可以容纳在柔性导管轴内。 可操纵的切割装置可以产生允许进入用于去除组织的装置的路径，和/或附加用于递送疗法的装置，例如填充材料和/或假体。 还公开了使用该系统访问椎体内部或椎间盘空间的方法，以及使用该系统治疗脊柱障碍的方法。

    IMPLANTABLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENTS
    6.
    发明申请
    IMPLANTABLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENTS 审中-公开
    用于输送治疗剂的可植入装置

    公开(公告)号：WO2009055015A1

    公开(公告)日：2009-04-30

    申请号：PCT/US2008/012093

    申请日：2008-10-24

    Applicant: SYNECOR, LLC ,  WILLIAMS, Michael, S. ,  CARLYLE, Wenda

    Inventor： WILLIAMS, Michael, S. ,  CARLYLE, Wenda

    IPC: A61N1/00

    CPC classification number: A61N1/05 ,  A61N1/057 ,  A61N1/375

    Abstract: A percutaneously implantable device for the treatment of a cardiac condition or other disease is disclosed herein, the device capable of delivery and maintenance of a therapeutic scaffold. A therapeutic scaffold may comprise viable tissue to impart or restore normal cardiac function, or other therapeutic agent for the treatment of disease or injury. Viable tissue may comprise a pacemaker gene or other genes intended to impart a pacemaker function to either host tissue or transplanted tissue, or both. Further, a device according to the invention may be used for the implantation and maintenance of viable tissue to induce or enhance muscle contraction of a subject for the treatment of a disease or disorder.

    Abstract translation: 本文公开了一种用于治疗心脏病或其他疾病的经皮植入装置，该装置能够递送和维持治疗性支架。 治疗性支架可以包括赋予或恢复正常心脏功能的活组织，或用于治疗疾病或损伤的其它治疗剂。 可行的组织可以包括起搏器基因或旨在赋予宿主组织或移植组织或两者的起搏器功能的其它基因。 此外，根据本发明的装置可用于植入和维持活组织以诱导或增强受试者的肌肉收缩以用于治疗疾病或病症。

    SYSTEMS AND METHODS FOR RESTORING FUNCTION OF DISEASED BOWEL
    9.
    发明申请
    SYSTEMS AND METHODS FOR RESTORING FUNCTION OF DISEASED BOWEL 审中-公开
    系统和方法，用于恢复失去知觉的BOWEL功能

    公开(公告)号：WO2008005510A2

    公开(公告)日：2008-01-10

    申请号：PCT/US2007/015526

    申请日：2007-07-06

    Applicant: SYNECOR, LLC ,  WILLIAMS, Michael, S. ,  FIFER, Daniel, W. ,  ATHAS, William, L. ,  STACK, Richard, S. ,  PRYOR, Aurora

    Inventor： WILLIAMS, Michael, S. ,  FIFER, Daniel, W. ,  ATHAS, William, L. ,  STACK, Richard, S. ,  PRYOR, Aurora

    IPC: A61B17/11 ,  A61F2/04

    CPC classification number: A61F2/04 ,  A61B17/1114 ,  A61B2017/00867 ,  A61F2/07

    Abstract: In a first embodiment of a system for treating diseased bowel, a pair of incisions are formed on opposite ends of a diseased section of bowel. A tubular bypass implant is positioned in the bowel such that its ends are anchored within the bowel and such that an intermediate section of the implant is positioned external to the bowel such that bowel contents flow through the implant and thus around the diseased bowel section. In a second embodiment, the diseased section of bowel is removed and a system is implanted for joining limbs of the resected bowel together to form an anastomosis. In the preferred anastomosis system, the limbs of the resected bowel are positioned between a tubular sleeve extending through the bowel and a tubular cuff positioned around the bowel.

    Abstract translation: 在用于治疗患病肠的系统的第一实施例中，在肠的患病部分的相对端上形成一对切口。 管状旁路植入物定位在肠中，使得其端部锚定在肠内并且使得植入物的中间部分位于肠的外部，使得肠内容物流过植入物并且因此围绕患病的肠部分。 在第二实施例中，移除肠的患病部分并植入系统以将切除的肠的肢体连接在一起以形成吻合。 在优选的吻合系统中，切除的肠的四肢位于延伸穿过肠的管状套管和位于肠周围的管状套囊之间。

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