公开(公告)号：WO2019079082A1

公开(公告)日：2019-04-25

申请号：PCT/US2018/055128

申请日：2018-10-10

Applicant: BIOSENSE WEBSTER (ISRAEL) LTD. ,  SCHULTZ, Jeffrey

Inventor： SCHULTZ, Jeffrey ,  ROUSU, Corey ,  GHIDOLI, Daniele ,  JUNG, Simon ,  CLARK, Jeffrey

IPC: A61M25/01 ,  A61B1/005 ,  A61B17/00

CPC classification number: A61M25/0136 ,  A61B1/0052 ,  A61B5/01 ,  A61B5/0422 ,  A61B5/06 ,  A61B5/6852 ,  A61B5/6869 ,  A61B18/1492 ,  A61B2017/00092 ,  A61B2017/00327 ,  A61B2017/0046 ,  A61B2017/00477 ,  A61B2017/12054 ,  A61B2018/00029 ,  A61B2018/00172 ,  A61B2018/00821 ,  A61B2217/007 ,  A61M25/0147 ,  A61N1/056 ,  A61N1/0565 ,  A61N1/057

Abstract: A steerable catheter (10) is disclosed, having an elongated, tubular catheter body (14) with at least one deflection member (30) slidably disposed within a lumen (26, 28), secured at a distal end to a tip section (16) and terminating in an interconnect (46) at a proximal end and a handle (12) releasably attached to the proximal end of the catheter body. The handle has at least one sliding member (54) coupled to an actuator (18), such that manipulation of the actuator causes relative longitudinal movement with respect to the handle, wherein the interconnect and the sliding member engage when the handle is attached to the catheter body so that the relative longitudinal movement of the sliding member is transmitted to the deflection member and wherein the interconnect and the sliding member disengage when the handle is released from the catheter body.

公开(公告)号：WO2018080894A1

公开(公告)日：2018-05-03

申请号：PCT/US2017/057416

申请日：2017-10-19

Applicant: KUSUMOTO, Walter

Inventor： KUSUMOTO, Walter

IPC: A61N1/05 ,  A61M25/01 ,  A61M39/02 ,  A61M39/06

CPC classification number: A61N1/057 ,  A61N1/0563 ,  A61N2001/0582

Abstract: A lead wire associated with a pacemaker, implantable cardiac defibrillator or other cardiac electric signal source is provided with a protector tube overlying at least a portion of the lead wire. In one embodiment, this protector tube is provided as a sheath tube portion of a sheath assembly along with a valve body. The valve body of the sheath assembly is fracturable and removable away from the sheath tube, leaving the sheath tube upon the lead wire as a protector tube. In other embodiments, a separate protector tube is provided and fed over the lead wire and through a sheath assembly until placed where desired. A grommet and/or plug can be provided at a proximal end of the protector tube for anchoring of the protector tube in a desired location and for plugging the protector tube, while also accommodating the lead wire passing therethrough.

Abstract translation: 与起搏器，植入式心脏除颤器或其他心脏电信号源相关联的导线设置有覆盖导线的至少一部分的保护器管。 在一个实施例中，该保护器管作为护套组件的护套管部分与阀体一起提供。 护套组件的阀体是可断开的并可远离护套管移除，并将护套管留在导线上作为保护管。 在其他实施例中，提供单独的保护器管并且在引线上并且通过护套组件被馈送直到放置在期望的位置。 可以在保护器管的近端设置护环和/或插头，用于将保护器管锚定在期望的位置并且用于堵塞保护器管，同时还容纳穿过其中的引线。

公开(公告)号：WO2016081449A1

公开(公告)日：2016-05-26

申请号：PCT/US2015/061072

申请日：2015-11-17

Applicant: MEDTRONIC, INC.

Inventor： GARDESKI, Kenneth C. ,  GRENZ, Nathan A. ,  SHEN, Xiaonan ,  LENERS, Michael R. ,  RONNING, Lonnie D.

IPC: A61N1/05

CPC classification number: A61F2/95 ,  A61N1/056 ,  A61N1/057 ,  A61N2001/0585

Abstract: A delivery tool of a system for deploying medical diagnostics and/or therapy includes a deployment member and a sheath. An elastic cantilever element secured to a tubular sidewall of the deployment member, in proximity to a distal opening of a lumen formed by the sidewall, is spring biased to extend outward from the sidewall. When the cantilever element is received within the sheath, a sheath sidewall pushes the cantilever element inward, against the spring bias thereof, and a radius of curvature of the cantilever element approximately conforms to that of an outer surface of the deployment member sidewall. A helical track for receiving passage of a medical device helix fixation element therein may extend around a perimeter of the deployment member lumen, wherein a distal terminal end of the track is located in close proximity to the distal opening and generally opposite a free end of the cantilever element.

Abstract translation: 用于部署医学诊断和/或治疗的系统的递送工具包括展开构件和护套。 固定到展开构件的管状侧壁上的弹性悬臂元件，靠近由侧壁形成的内腔的远侧开口，被弹性偏置以从侧壁向外延伸。 当悬臂元件被容纳在护套内时，护套侧壁将悬臂元件抵靠其弹簧偏压向内推动，并且悬臂元件的曲率半径大致与展开构件侧壁的外表面的曲率半径一致。 用于接纳医疗装置螺旋固定元件的通道的螺旋轨道可以围绕展开构件内腔的周边延伸，其中轨道的远端终端位于紧邻远端开口并且大致相对于远端开口的自由端 悬臂元件

公开(公告)号：WO2016055514A1

公开(公告)日：2016-04-14

申请号：PCT/EP2015/073132

申请日：2015-10-07

Applicant: NEUROLOOP GMBH

Inventor： PLACHTA, Dennis ,  GIERTHMÜHLEN, Mortimer ,  STIEGLITZ, Thomas ,  ZENTNER, Josef

IPC: A61N1/05

CPC classification number: A61N1/3605 ,  A61N1/05 ,  A61N1/057 ,  A61N1/059 ,  A61N1/326 ,  A61N1/37247

Abstract: Beschrieben wird eine implantierbare Elektrodenanordnung mit einem zumindest bereichsweise aus biokompatiblen Polymer bestehenden Trägersubstrat, auf dessen Trägersubstratoberfläche zumindest bereichsweise eine frei zugängliche Elektrodenoberfläche einer auf dem Trägersubstrat aufgebrachten oder in das Trägersubstrat integrierten Elektrode vorhanden ist. Ferner wird ein Verfahren zur Herstellung der implantierbaren Elektrodenanordnung erläutert. Die Erfindung zeichnet sich dadurch aus, dass die Elektrode eine metallische Basisplatte mit einer ebenen Ober- und Unterseite aufweist, mit wenigstens einem die Oberseite orthogonal, lokal überragenden Strukturelement, dass die ebene Oberfläche der metallischen Basisplatte parallel zur Trägersubstratoberfläche orientiert ist, und dass die metallische Basisplatte vollständig von dem biokompatiblen Polymer mittel- und/oder unmittelbar umschlossen ist mit Ausnahme eines ersten Oberflächenbereiches des wenigstens einen Strukturelements, der der Trägersubstratoberfläche zugewandt orientiert ist und der frei zugänglichen Elektrodenoberfläche entspricht.

Abstract translation: 描述具有至少部分地由至少一个可自由接近的电极表面施加到载体衬底或集成到载体基底电极层被部分地设置在载体基材表面上生物相容的聚合物载体基板的植入电极阵列。 此外，可植入电极阵列的制造方法进行说明。 本发明的特征在于，所述电极具有一个平的顶面和底面的金属的底座板，有至少一个顶部正交，本地优越的结构元件，所述金属的底座板的平坦表面的取向平行于所述支撑基板的表面，并且所述金属 底板完全培养基中的生物相容的聚合物和/或直接包围除了至少一个结构元件的第一表面区域，所述载体基片表面面取向，并对应于自由接近电极表面。

公开(公告)号：WO2016032637A1

公开(公告)日：2016-03-03

申请号：PCT/US2015/040870

申请日：2015-07-17

Applicant: MEDTRONIC, INC.

Inventor： GRUBAC, Vladimir ,  ANDERSON, Thomas A. ,  KUHN, Jonathan L. ,  SWENSON, Richard W. ,  CAMPBELL, Michael P.

IPC: A61N1/375

CPC classification number: A61N1/057 ,  A61N1/362 ,  A61N1/3756

Abstract: A fixation member component, for example, employed by a relatively compact implantable medical device, includes a plurality of fingers; each finger includes a first segment extending from a fixed end of the corresponding finger, and a second segment extending from the corresponding first segment to a free end of the corresponding finger. Each first segment is elastically deformable from a relaxed to an extended condition, and from the relaxed to a compressed condition, and includes a peripheral portion and a central cut-out portion, framed by the peripheral portion. In the compressed condition, a free tip of the cut-out portion of some or all of the fingers may lodge against opposing tissue surfaces, via a spring force of the compressed fingers. Each second segment and cut-out portion is preferably configured to prevent penetration thereof within tissue at the implant site.

Abstract translation: 例如由相对紧凑的可植入医疗装置使用的固定构件部件包括多个手指; 每个手指包括从相应手指的固定端延伸的第一段和从对应的第一段延伸到相应手指的自由端的第二段。 每个第一段可从松弛到伸长状态弹性变形，并且从松弛到可压缩状态，并且包括由周边部分构成的周边部分和中央切口部分。 在压缩状态下，部分或全部手指的切口部分的自由尖端经由压缩手指的弹簧力抵靠在相对的组织表面上。 每个第二段和切口部分优选地构造成防止在植入部位的组织内的穿透。

公开(公告)号：WO2013035092A3

公开(公告)日：2015-04-16

申请号：PCT/IL2012000336

申请日：2012-09-09

Applicant: ENOPACE BIOMEDICAL LTD ,  DAGAN AMIR ,  ELAZAR MOSHE ,  HANANI NITAI ,  ARIAV GAL ,  MEIRI ODED ,  GINDIN IGOR ,  BERNSHTEIN VADIM ,  ARMONY NIR ,  GROSS YOSSI ,  REISNER YOTAM ,  GLASBERG OFFER

Inventor： DAGAN AMIR ,  ELAZAR MOSHE ,  HANANI NITAI ,  ARIAV GAL ,  MEIRI ODED ,  GINDIN IGOR ,  BERNSHTEIN VADIM ,  ARMONY NIR ,  GROSS YOSSI ,  REISNER YOTAM ,  GLASBERG OFFER

IPC: A61F2/06

CPC classification number: A61N1/40 ,  A61B5/0215 ,  A61B5/04 ,  A61B5/0402 ,  A61B5/0816 ,  A61F2/82 ,  A61F2/915 ,  A61F2002/8483 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/0002 ,  A61F2250/0018 ,  A61N1/05 ,  A61N1/0514 ,  A61N1/0558 ,  A61N1/056 ,  A61N1/057 ,  A61N1/36053 ,  A61N1/3756 ,  A61N2001/0585

Abstract: Apparatus and methods are provided for use with a blood vessel of a subject, including a stent (20) configured to be placed in the blood vessel. The stent includes at least first (32), second (34), and third (36) strut portions disposed along the stent. The first and second strut portions are coupled to one another at a first junction (37A) that facilitates bending of the first and second strut portions with respect to one another. The second and third strut portions are coupled to one another at a second junction (37B) that facilitates bending of the second and third strut portions with respect to one another. At least one electrode (22) is disposed on at least an outer surface of the stent. Other applications are also described.

Abstract translation: 提供了与被检体的血管一起使用的装置和方法，包括构造成放置在血管中的支架（20）。 所述支架包括沿支架设置的至少第一（32），第二（34）和第三（36）支柱部分。 第一和第二支柱部分在促进第一和第二支柱部分相对于彼此的弯曲的第一接合部（37A）处彼此联接。 第二和第三支柱部分在促进第二和第三支柱部分相对于彼此弯曲的第二接合部（37B）处彼此联接。 至少一个电极（22）设置在支架的至少外表面上。 还描述了其它应用。

公开(公告)号：WO2015020970A1

公开(公告)日：2015-02-12

申请号：PCT/US2014/049627

申请日：2014-08-04

Applicant: MEDTRONIC, INC.

Inventor： OSTER, Daniel, C.

IPC: A61N1/05

CPC classification number: A61M25/02 ,  A61B17/3415 ,  A61M25/0045 ,  A61M25/0082 ,  A61M25/04 ,  A61M2025/0046 ,  A61M2025/028 ,  A61M2025/0286 ,  A61N1/0558 ,  A61N1/057 ,  A61N2001/0582

Abstract: An introducer assembly that may be employed to implant a medical device includes an introducer shaft, and an anchor sleeve and a deployment tool mounted on the shaft. According to some methods, the sleeve is deployed onto an elongate body of the medical device, after the body has been advanced through a lumen of the introducer shaft and to an implant site within a body of a patient, by pulling the introducer shaft proximally, out from the body of the patient, while holding the deployment tool in place, relative to the advanced body of the device.

Abstract translation: 可用于植入医疗装置的导引器组件包括引导器轴，以及安装在轴上的锚定套筒和展开工具。 根据一些方法，通过将引导器轴向近侧拉动，在主体已经推进穿过导引器轴的内腔和患者身体内的植入部位之后，将套管展开到医疗装置的细长主体上， 从患者的身体出来，同时将部署工具相对于设备的高级身体保持在适当位置。

公开(公告)号：WO2014089545A1

公开(公告)日：2014-06-12

申请号：PCT/US2013/073761

申请日：2013-12-07

Applicant: PURDUE RESEARCH FOUNDATION

Inventor： MERCER, Elizabeth ,  ZHANG, Johnny ,  PELLETTIERE, Joseph, Michael ,  LEE, Jason, Wenhaw

IPC: A61N1/372 ,  A61N1/08 ,  A61N1/04 ,  A61B17/00

CPC classification number: G01N3/08 ,  A61B17/3468 ,  A61B2090/064 ,  A61N1/05 ,  A61N1/057 ,  A61N2001/0578 ,  G01M99/007 ,  G01N3/04 ,  G01N19/04 ,  G01N2203/0017

Abstract: A lead fixation and stability feedback assembly for testing stability and anchoring of a fixation tip of a distal end of an implantable lead to a tissue is disclosed. The assembly includes a first member including a first coupling arrangement configured to couple to a proximal end of an implantable lead, wherein the proximal end of the implantable lead is coupled to a distal end of the implantable lead configured to be anchored to a tissue, and a second member including a second coupling arrangement configured to couple the first member to the second member, the second coupling arrangement configured to decouple the second member from the first member when a predetermined force is applied to pull the second member away from the first member to thereby test the anchoring of the distal end of the implantable lead to the tissue.

Abstract translation: 公开了一种引导固定和稳定性反馈组件，用于测试可植入引线的远端的固定尖端到组织的稳定性和锚定。 组件包括第一构件，其包括被配置为联接到可植入引线的近端的第一联接装置，其中可植入引线的近端联接到构造成锚定到组织​​的可植入引线的远端，以及 第二构件，包括被配置为将第一构件联接到第二构件的第二联接装置，第二联接装置被配置为当施加预定的力以将第二构件从第一构件拉离到第一构件时将第二构件与第一构件分离， 从而测试可植入引线的远端锚定到组织​​上。

公开(公告)号：WO2013136312A3

公开(公告)日：2014-03-13

申请号：PCT/IB2013052101

申请日：2013-03-15

Applicant: KRISHNAN SUBRAMANIAM CHITOOR

Inventor： KRISHNAN SUBRAMANIAM CHITOOR ,  PATIL NITIN

IPC: A61N1/37 ,  A61N1/05

CPC classification number: A61N1/059 ,  A61N1/05 ,  A61N1/057 ,  A61N1/3706 ,  A61N1/371 ,  A61N2001/0585

Abstract: A lead for in vivo procedures for stimulation of a tissue is provided that has stimulating electrodes and a fixation mechanism disposed at a distal end of the lead. The fixation mechanism includes a fixation component disposed on an opposite side with respect to an active surface of the stimulation electrodes. The lead fixation mechanism when deployed disposes the active surface of stimulation electrodes onto a tissue region opposite to the fixation component. A system and a method for optimally positioning the lead for stimulation of the tissue are also provided.

Abstract translation: 提供用于刺激组织的体内程序的引导件，其具有设置在引线的远端处的刺激电极和固定机构。 固定机构包括相对于刺激电极的有效表面设置在相对侧的固定部件。 引导固定机构在部署时将刺激电极的活性表面配置到与固定部件相对的组织区域上。 还提供了用于最佳地定位用于刺激组织的引线的系统和方法。

公开(公告)号：WO2013142616A2

公开(公告)日：2013-09-26

申请号：PCT/US2013033180

申请日：2013-03-20

Applicant: BOSTON SCIENT NEUROMDULATON CORP

Inventor： PIANCA ANNE MARGARET ,  CHEN ROGER

IPC: A61N1/05

CPC classification number: A61N1/057 ,  A61N1/0558 ,  A61N2001/0582

Abstract: A lead anchor includes a body having an outer surface, a top end, a front side, a first end, and a second end opposite to the first end. The body defines a lead slot configured and arranged to receive a lead. The lead slot defines an elongated opening extending along the front side of the body from the first end to the second end. A transverse lumen extends from the top end of the body and intersects the lead slot. An exterior member is disposed around at least a portion of the body. The exterior member is formed of a biocompatible material. A fastener is disposed in the transverse lumen. The fastener is configured and arranged for fastening the received lead to the lead anchor by deforming a portion of the lead.

Abstract translation: 引线锚杆包括具有外表面，顶端，前侧，第一端和与第一端相对的第二端的本体。 主体限定了配置和布置成接收引线的引线槽。 引导槽限定从主体的第一端延伸到第二端的细长开口。 横向内腔从主体的顶端延伸并与引线槽相交。 外部构件围绕身体的至少一部分设置。 外部构件由生物相容性材料形成。 紧固件设置在横向内腔中。 紧固件被构造和布置成用于通过使引线的一部分变形来将接收到的引线固定到引线锚定件。