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1.发明申请SUSTAINED RELEASE NANOCOMPOSITE, A PROCESS FOR PRODUCING THE SAME AND USE THEREOF 审中-公开可持续发行纳米复合材料，其生产方法及其应用
公开(公告)号：WO2017021748A1
公开(公告)日：2017-02-09
申请号：PCT/HU2016/050034
申请日：2016-07-28
Applicant: SZEGEDI TUDOMÁNYEGYETEM
Inventor： DÉKÁNY, Imre , KRIZBAI, István , MAJLÁTH, Zsófia , TOLDI, József , VARGA, Noémi , VÉCSEI, László
CPC classification number: A61K9/5169 , A61K9/5146 , A61K9/5161 , A61K31/00
Abstract: The present invention relates to nanocomposites for the controlled delivery of active ingredients into the central nervous system. The nanocomposite according to the present invention comprises a biocompatible core part comprising biodegradable material, and polyelectrolytes able to form a electrostatic van der Waals interactions with the material of the core part. The core part of the nanocomposite is able to bind various pharmaceutical agents. The present invention also relates to a process for the preparation of the nanocomposite according to the present invention and to the use of the nanocomposite according to the present invention.
Abstract translation: 本发明涉及用于将活性成分控制递送到中枢神经系统中的纳米复合材料。 根据本发明的纳米复合材料包括包含可生物降解材料的生物相容性核心部分和能够与核心部分的材料形成静电范德华相互作用的聚电解质。 纳米复合材料的核心部分能够结合各种药剂。 本发明还涉及制备根据本发明的纳米复合材料的方法和本发明的纳米复合材料的用途。
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