PEPTIDES FOR USE IN THE TREATMENT OF CHOLERA

    公开(公告)号:WO2021010835A1

    公开(公告)日:2021-01-21

    申请号:PCT/NL2020/050469

    申请日:2020-07-16

    Abstract: The present invention relates to means and methods for the treatment of cholera. The current invention also provides for means and methods for the prevention of cholera. In particular, the means and methods of the current invention allows to target the bacteria that cause cholera, Vibrio cholerae , while not targeting other bacteria. Peptides are provided that can interfere with binding of Vibrio cholerae to the intestine thereby disrupting biofilm formation and/or colonization in the intestine can be disrupted, which is useful in the treatment or prevention of cholera. Means and methods to identify such peptides are provided as well.

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