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公开(公告)号:WO2023083826A1
公开(公告)日:2023-05-19
申请号:PCT/EP2022/081166
申请日:2022-11-08
Applicant: SMART PHOTONICS HOLDING B.V. , NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK (NWO) , TECHNISCHE UNIVERSITEIT EINDHOVEN
Inventor: MEIGHAN, Arezou
Abstract: An electro-optical modulator for a photonic integrated circuit. The electro-optical modulator comprising: a substrate; a first waveguide on a first portion of the substrate; a first electrode; a second waveguide on a second portion of the substrate; and a second electrode. A first electrical impedance value between the first electrode and the second electrode is different from a second electrical impedance value between the first electrode and the second electrode. The first electrical impedance value along a first axis perpendicular a light propagation axis of the first waveguide. The second electrical impedance value along a second axis perpendicular the light propagation axis of the first waveguide. The first axis spaced from the second axis along the light propagation axis of the first waveguide.
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公开(公告)号:WO2022173293A1
公开(公告)日:2022-08-18
申请号:PCT/NL2022/050063
申请日:2022-02-08
Applicant: TECHNISCHE UNIVERSITEIT EINDHOVEN , NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO
Abstract: The invention is directed to a thermochemical system such as a thermochemical heat battery that can efficiently operate at relative low temperatures. Accordingly, a system for thermochemical storage is provided which system comprises a thermochemical reactor and a water condenser for dehumidifying a gas stream comprising a condensing surface provided with a hygroscopic material.
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公开(公告)号:WO2021255283A1
公开(公告)日:2021-12-23
申请号:PCT/EP2021/066709
申请日:2021-06-18
Inventor: MISCHI, Massimo , SCHOOT, Benedictus
IPC: G06T7/00 , G06T7/20 , A61B5/00 , A61B8/08 , A61B2576/00 , A61B5/4356 , A61B8/485 , A61B8/5223 , G06T2207/10016 , G06T2207/10132 , G06T2207/20048 , G06T2207/30004 , G06T7/0012 , G16H50/30
Abstract: Image analysis method for quantitative assessment of a degree of coordination of uterine motion, comprising: obtaining a recording of a uterus; tracking, in the recording, at least two propagation waves of uterine motion in at least two different regions of the uterus and/or on at least two different times; and determining the degree of coordination of the uterine motion based on a similarity measure of at least two characteristics of the at least two propagation waves.
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公开(公告)号:WO2021239932A1
公开(公告)日:2021-12-02
申请号:PCT/EP2021/064318
申请日:2021-05-28
Applicant: DSM IP ASSETS B.V. , MAASTRICHT UNIVERSITAIR MEDISCH CENTRUM+ , TECHNISCHE UNIVERSITEIT EINDHOVEN , UNIVERSITY MAASTRICHT
Inventor: OEVERING, Hendrik , GELISSEN, Franciscus, Wilhelmus, Maria , THIES, Jens, Christoph , EMANS, Pieter , ROTH, Alex, Kristian , VAN DONKELAAR, Corrinus, Cornelis , ASIK, Emin, Erkan
Abstract: Present invention relates to an orthopedic implant having a bone anchoring part comprising a polymer composition comprising a biostable thermoplastic polyurethane (TPU) and 15-70 mass% of inorganic particles comprising zirconia. It was found that this relatively rigid anchoring part allows inserting an implant into a pre-drilled bone hole to form a firm and durable connection to bone, which may be visualized with for example X-ray or MRI methods. The thermoplastic polyurethane composition shows favorable properties, and offers freedom in design and dimensioning of the implant, and in making the implant with common techniques like injection molding. Especially if the implant comprises a cartilage replacing part made from a resilient thermoplastic material compatible with the polyurethane-zirconia composition, like a more flexible TPU composition, the implant may be made with a 2-component injection molding technique. In other aspects, the invention relates to a method of making said orthopedic implant comprising a bone anchoring part with a multi-component injection molding process. The invention further relates to a surgical kit of parts comprising orthopedic implants of the invention, and to the use of an implant or a surgical kit of the invention in orthopedic surgery.
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公开(公告)号:WO2020067891A1
公开(公告)日:2020-04-02
申请号:PCT/NL2019/050641
申请日:2019-09-24
Applicant: TECHNISCHE UNIVERSITEIT EINDHOVEN
Inventor: KURNIAWAN, Nicholas Agung , ZHANG, Shuaizhong , SABERI, Aref , DEN TOONDER, Jacob Marinus Jan
IPC: B01F13/08
Abstract: A device (1) for providing controlled stirring comprising: an electromagnetic system (3) arranged for realising a magnetic field; and at least one stirring chamber (5) comprising at least one Suspended Magnetically Actuatable Pillar (7), SMAP (7), suspended in said chamber (5) from a support (9) and configured, in use, in said magnetic field such that said SMAP (7) is magnetically actuated, by said magnetic field, for providing said controlled stirring. A method using said device (1) for controlled stirring in a stirring chamber (5), said method comprising the steps of: realising, by said electromagnetic system (3), said magnetic field; and magnetically actuating, by said magnetic field, said SMAP (7), for realising said controlled stirring in said stirring chamber (5). The invention further relates to the use of a SMAP (7), for controlled stirring in a stirring chamber (5), wherein said SMAP (7) is suspended from a support (9), wherein said SMAP (7) is magnetically actuated, by a magnetic field, for said controlled stirring.
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公开(公告)号:WO2020021008A1
公开(公告)日:2020-01-30
申请号:PCT/EP2019/070038
申请日:2019-07-25
Applicant: TECHNISCHE UNIVERSITEIT EINDHOVEN
Inventor: COEHOORN, Reinder , BOBBERT, Peter Arnold , LIU, Feilong , COTTAAR, Jeroen
IPC: G06F17/50
Abstract: Three-dimensional master equation modeling for disordered semiconductor devices is provided. Charge transport is modeled as incoherent hopping between localized molecular states, and recombination is modeled as a nearest-neighbor process where an electron at a first location and a hole at a second location can recombine at either the first location or the second location. Here the first and second locations are any pair of nearest neighbor locations. We have found that this nearest neighbor recombination model performs substantially better than the conventional local recombination model where an electron and a hole must be at the same location to recombine. The recombination rate is modeled as a product of a prefactor ϒ, hopping rates and state occupancies. Importantly, we have found that sufficient simulation accuracy can be obtained by taking ϒ to be given by an empirically derived analytic expression.
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公开(公告)号:WO2019145142A1
公开(公告)日:2019-08-01
申请号:PCT/EP2019/050362
申请日:2019-01-09
IPC: A61B5/1455 , A61B5/00 , A61B5/024
CPC classification number: A61B5/14551 , A61B5/02416 , A61B5/7207
Abstract: The present invention relates to a device, system and method for determining at least one vital sign of a subject. The device (130) comprises an input interface (131) configured to obtain at least three detection signals derived from detected electromagnetic radiation transmitted through or reflected from a skin region of a subject, wherein each detection signal comprises wavelength-dependent reflection or transmission information in a different wavelength channel, a transformation unit (132) configured to transform the at least three detection signals into at least three transformed detection signals by temporally normalizing the at least three detection signals or applying a non-linear transfer function on the at least three detection signals, a projection unit (133) configured to project the at least three transformed detection signals into at least two projected signals in a subspace orthogonal to a predetermined distortion direction, and a vital sign determination unit (134) configured to determine an indicator or concentration of blood components or species as vital sign from said at least two projected signals by indirectly determining the relative strength of a pulsatile component in said at least two projected signals.
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公开(公告)号:WO2019053287A1
公开(公告)日:2019-03-21
申请号:PCT/EP2018/075225
申请日:2018-09-18
Applicant: TECHNISCHE UNIVERSITEIT EINDHOVEN
Inventor: KOURIS, Panagiotis , BOOT, Michael Dirk , HENSEN, Emiel Jan Maria , OEVERING, Hendrik
IPC: C10L1/02
Abstract: The present invention relates to a process the production of a crude liquid lignin oil (CLO), said process comprises the steps of providing a lignin-rich solid feedstock and subjecting the lignin-rich solid feedstock to a treatment in a polar organic solvent in the absence of an effective amount of added reaction promoter, such as a heterogeneous and/or homogeneous catalyst and/or hydrogen, and providing a lignin composition, said treatment comprises a step of contacting said lignin-rich solid feedstock with a polar organic solvent under operating conditions of an operating temperature up to 210 °C, an operating pressure lower than 50 bar and a residence time up to 240 minutes, wherein the ratio (w/v) of lignin (in lignin- rich feedstock) to polar organic solvent ranges between 1:1.5 and 1:15, or between 1:2 and 1:10 or between 1:2 and 1:5.
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公开(公告)号:WO2019038375A1
公开(公告)日:2019-02-28
申请号:PCT/EP2018/072758
申请日:2018-08-23
Applicant: TECHNISCHE UNIVERSITEIT EINDHOVEN
Inventor: TENDA, Keisuke , ARTS, Remco , CITTERIO, Daniel , TOMIMURO, Kosuke , MERKX, Maarten
IPC: C12Q1/66 , G01N33/542
Abstract: A fully integrated Òsample-in-signal-out Ó microfluidic paper-based analytical devices are provided relying on bioluminescence resonance energy transfer (BRET) switches for target analyte recognition and colorimetric signal generation. Simultaneous colorimetric detection and quantification of multiple antibodies in a single drop of whole blood is shown. The devices make use of BRET-based antibody sensing proteins integrated into vertically assembled layers of functionalized porous layer(s) of material. The device enables sample volume independent, eliminates addition of reagents to the sample, and has on-device blood plasma separation. User operation is a single drop of a sample and the acquisition of a photograph after sample introduction, with no requirement for precise pipetting, liquid handling or analytical equipment except for a camera. Using different antibodies as targets, simultaneous detection in whole blood was achieved. This device is believed to be ideally suited for user-friendly point-of-care-testing in low- resource environments based on BRET-sensors.
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公开(公告)号:WO2018172352A1
公开(公告)日:2018-09-27
申请号:PCT/EP2018/057012
申请日:2018-03-20
Abstract: There is provided an apparatus comprising a control unit and a method of operating the apparatus to determine a health status of an infant. The method comprises acquiring contextual information associated with the infant (302) and acquiring at least one heart rate variability signal from the infant (304). The at least one heart rate variability signal acquired from the infant is processed to determine a heart rate variability feature (306) and the determined heart rate variability feature is assigned to a class according to the acquired contextual information (308). The determined heart rate variability feature is compared to one or more corresponding heart rate variability features stored in the same class as the determined heart rate variability in a memory (310) and a health status of the infant is determined based on the comparison (312).
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