公开(公告)号：WO2017189772A1

公开(公告)日：2017-11-02

申请号：PCT/US2017/029713

申请日：2017-04-26

Applicant: TELA BIO, INC.

Inventor： GREENHALGH, Skott ,  ROMANO, John-paul ,  SPEICHER, Travis

IPC: A61F2/00

Abstract: Materials for soft tissue repair, and in particular, material for hernia repair. These materials may be configured as an implant, such as a graft, that may be implanted into a patient in need thereof, such as a patient having a hernia or undergoing a hernia repair surgical procedure. These grafts may include a first layer comprising a substrate (e.g., mesh) and a second layer comprising a sheet of anti-adhesive material. The layers may be attached with a plurality of relatively small attachment sites that are separated by regions in which the two layers are not attached, to provide a highly compliant graft.

Abstract translation:

用于软组织修复的材料，特别是用于疝修复的材料。 这些材料可以被配置为植入物，诸如移植物，其可以被植入到有需要的患者中，诸如患有疝或正在经历疝修复外科手术的患者。 这些移植物可以包括包含基底（例如网）的第一层和包含抗粘连材料片的第二层。 这些层可以附着有多个相对较小的附着位点，这些附着位点由两层未附着的区域分开，以提供高度顺应性的移植物。

公开(公告)号：WO2017015421A1

公开(公告)日：2017-01-26

申请号：PCT/US2016/043240

申请日：2016-07-21

Applicant: TELA BIO, INC.

Inventor： GREENHALGH, Skott ,  ROMANO, John-Paul

IPC: A61F2/00

CPC classification number: A61F2/0063 ,  A61F2/00 ,  A61F2002/0068 ,  A61F2210/0004 ,  A61F2210/0057 ,  A61F2210/0076 ,  A61F2250/0018 ,  A61F2250/0028 ,  A61F2250/0029 ,  A61F2250/003 ,  A61L31/005 ,  A61L31/048 ,  A61L31/146 ,  A61L2430/34 ,  D05B93/00 ,  D05C17/00

Abstract: Compliance control stitch patterns sewn or embroidered into biotextile or medical textile substrates impart reinforcing strength, and stretch resistance and control into such substrates. Compliance control stitch patterns may be customizable to particular patients, substrate implantation sites, particular degenerative or diseased conditions, or desired time frames. Substrates having compliance control stitch patterns sewn or embroidered into them may be used in tissue repair or tissue reconstruction applications.

Abstract translation: 缝合或绣成生物纺织品或医用纺织品基材的合规性控制针迹图案赋予增强强度，并且对这些基材进行拉伸和控制。 适应性控制针迹图案可以针对特定患者，底物植入部位，特定退行性疾病或病变状况或期望的时间框架进行定制。 具有缝合或绣在其中的顺应性控制缝合图案的基底可用于组织修复或组织重建应用。

公开(公告)号：WO2017004136A1

公开(公告)日：2017-01-05

申请号：PCT/US2016/039984

申请日：2016-06-29

Applicant: TELA BIO, INC.

Inventor： GREENHALGH, Skott ,  ROMANO, John-Paul

IPC: D05B1/12 ,  A61F2/00

CPC classification number: A61F2/0063 ,  A61F2002/0068 ,  A61F2220/0075 ,  D05B1/12 ,  D05B93/00

Abstract: Stitching patterns overlap to produce a corner-locked stitch pattern. The corner-locked stitch pattern includes one or more thread interlace points, and one or more overlays of threads from overlapping patterns. A network of corner-lock stitch patterns produces a mesh, which may be embroidered into a substrate, such as a medical textile or biotextile. Corner-lock stitch patterns resist puncture-induced and tension-induced deformation of mesh pores between corner-locked stitch patterns, and may be used to modulate compliance and enhance strength properties of a substrate into which they are sewn.

Abstract translation: 缝合图案重叠以产生拐角锁定针迹图案。 角锁定针迹图案包括一个或多个线程交错点，以及来自重叠图案的线程的一个或多个覆盖层。 角锁定针迹图案的网络产生网孔，其可以被绣制到诸如医用纺织品或生物纺织品的基底中。 角锁定针迹图案可以抵抗穿刺引起的和拉伸引起的角间锁定针迹图案之间的网孔的变形，并且可以用于调节其缝合的基底的顺应性和增强强度性质。