公开(公告)号：WO2022056394A1

公开(公告)日：2022-03-17

申请号：PCT/US2021/050088

申请日：2021-09-13

Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN

Inventor： XU, Zhen ,  NOLL, Douglas ,  HALL, Timothy, L.

IPC: A61N7/02 ,  A61B5/055 ,  A61B90/00 ,  G01R33/48

Abstract: A transcranial magnetic resonance (MR)-guided histotripsy (tcMRgHt) system is provided. Using electronic steering only, the tcMRgHt system is configured to create lesions of 25.5 mm in the transverse plane and 50 mm in the axial plane through the skull of a patient. This disclosure provides the design, fabrication, acoustic characterization, and MR compatibility assessment of tcMRgHt systems for histotripsy.