公开(公告)号：WO2021222718A1

公开(公告)日：2021-11-04

申请号：PCT/US2021/030112

申请日：2021-04-30

Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN

Inventor： FAN, Xudong ,  CHEN, Qiushu ,  SUN, Yunlu

IPC: G01N21/64

Abstract: The present disclosure provides an imaging system. The imaging system may include a laser cavity that is configured to receive a biological sample, where the biological sample is treated with a dye; an excitation light source that is configured to direct energy at the laser cavity so as to cause an emission from the biological sample, where the emission includes a laser emission at a first spectral band and a fluorescence emission at a second spectral band; a first detector that is configured to measure the laser emission generated by the biological sample; a second detector that is configured to measure the fluorescence emission generated by the biological sample; a splitter that is configured to direct the laser emission to the first detector and the fluorescence emission to the second detector; and a controller interfaced with the excitation light source, the first detector, and the second detector.