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公开(公告)号:WO2016009227A1
公开(公告)日:2016-01-21
申请号:PCT/GB2015/052089
申请日:2015-07-17
Applicant: THE UNIVERSITY OF LIVERPOOL
Inventor: RANNARD, Steve , FORD, Jane , ROGERS, Hannah , CHAMBON, Pierre , GIARDIELLO, Marco , OWEN, Andrew , KITTERINGHAM, Neil
IPC: A61K9/51 , A61K47/48 , A61K31/427 , A61K31/4745 , A61K31/513 , A61K31/536 , C08F2/38 , C08F220/10 , C08G63/08 , C08G83/00 , C08L33/10 , A61P35/00 , A61P31/18
CPC classification number: A61K9/5146 , A61K9/5138 , A61K9/5153 , A61K9/5192 , A61K31/192 , A61K31/427 , A61K31/4745 , A61K31/513 , A61K31/536 , C08F2/38 , C08F220/20 , C08F220/34 , C08F2220/1825 , C08F2222/1013 , C08F2438/01 , C08G63/08 , C08G81/025 , C08G83/003 , C08L33/10 , C08L71/02
Abstract: Particles comprising a branched polymer and either a block copolymer or a linear dendritic hybrid represent a category of useful materials. They may be used in for example drug delivery applications. They may be prepared by a method comprising the steps of: dissolving the branched polymer and block copolymer or linear dendritic hybrid, and optionally other component(s),in a solvent to form a solution; adding said solution to a different liquid; and removing said solvent to form a dispersion of co-precipitated particles.
Abstract translation: 包含支链聚合物和嵌段共聚物或线性树枝状杂化物的颗粒代表一类有用的材料。 它们可以用于例如药物递送应用。 它们可以通过包括以下步骤的方法制备:将支化聚合物和嵌段共聚物或线性树枝状杂化物和任选的其它组分溶解在溶剂中以形成溶液; 将所述溶液加入到不同的液体中; 并除去所述溶剂以形成共沉淀颗粒的分散体。