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公开(公告)号：WO2020011425A1
公开(公告)日：2020-01-16
申请号：PCT/EP2019/062322
申请日：2019-05-14
发明人： LI, Yajuan , YI, Shangchun
摘要： An oral care composition is disclosed a copolymer of methyl vinyl ether and maleic anhydride, polyvinylpyrrolidone, an ethoxylated alkyl sulfate anionic surfactant having a formula RO(CH 2 CH 2 O) n SO 3 M, wherein R is an alkyl or alkenyl group having from 8 to 18 carbon atoms; M is a solubilising cation comprising sodium, potassium, ammonium, substituted ammonium or mixtures thereof; n is the degree of ethoxylation of from 0.5 to 3, a pigment having a hue angle, h, in the CIELAB system of from 220 to 320 degrees, and a physiologically acceptable carrier, wherein the copolymer and the polyvinyl pyrrolidone are present in a weight ratio of from 1:20 to 1:4.
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2.发明申请
公开(公告)号：WO2020053019A1
公开(公告)日：2020-03-19
申请号：PCT/EP2019/073351
申请日：2019-09-02
发明人： FANG, Yi , MENG, Sheng , YI, Shangchun
摘要： Disclosed is a method of determining efficacy of a cosmetic composition to inhibit an atmospheric pollutant from contacting skin, comprising the steps of: (i) filling a sample holder of known dimensions with known amount of said composition to form a layer of defined thickness therein, where said sample holder is amenable to fluorescence-based assay; (ii) depositing, on said layer, a known amount of a model fine particulate matter which resembles an atmospheric pollutant at least in size and which comprises a material responsive to fluorescence microscopy which is excitable by a wavelength (ʎ ex ) and which emits radiation (ʎ em ) where (ʎ ex ) ≠ (ʎ em ); (iii) irradiating said composition and said model fine particulate matter by said ʎ ex and recording intensity of fluorescence at ʎ em a plurality of times for a defined period during which said model fine particulate matter interacts with said layer; and, (iv) determining, corrected intensity of fluorescence at ʎ em by the following equation; corrected Intensity = recorded intensity / average transmittance where said average transmittance is the average of the transmittance of the composition measured at ʎ ex and ʎ em determined by Beer-Lambert law by measuring the absorbance at ʎ ex and ʎ em , where the corrected intensity is inversely proportional to said efficacy of said composition.
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公开(公告)号：WO2019219393A1
公开(公告)日：2019-11-21
申请号：PCT/EP2019/061200
申请日：2019-05-02
发明人： CHEN, Guoqiang , FANG, Yi , HUANG, Nan , JI, Chengdong , MENG, Sheng , YI, Shangchun , YUAN, Caigen
摘要： Disclosed is an in vitro method to determine efficacy of a cosmetic composition or an active ingredient comprised therein to inhibit an atmospheric pollutant from contacting skin, comprising the steps of: (i) filling a sample holder of known dimensions with a known amount of said composition to form a layer of defined thickness therein; (ii) depositing, on said layer, a known amount of a model fine particulate matter which resembles a particulate atmospheric pollutant and is responsive to a spectroscopic or microscopic chemical imaging technique; (iii) performing said chemical imaging; (iv) for a defined period, recording and analyzing the interaction of said model fine particulate matter with and within said layer by the imaging technique, where interaction indicates the penetration speed of said model fine particulate matter in the layer; and, (v) ascertaining said efficacy from the information of step (iv) wherein the slope of a plot of data obtained from said imaging technique against time in the range of 1 to 100 minutes is indicative of short-term efficacy of said composition and the nature of the plot beyond 100 minutes is indicative of long- term efficacy and wherein long-term inhibition factor of said composition is calculated as follows: Long term inhibition factor = Formula (1) where, x is the distance between the bottom of the chamber and the assumed centre of the Gaussian distribution of the model fine particulate model in the layer, σ is the width of the Gaussian distribution and μ is the mean of the Gaussian distribution, where it is assumed that distribution of the model fine particulate matter in said layer follows Gaussian distribution.
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公开(公告)号：WO2019219392A1
公开(公告)日：2019-11-21
申请号：PCT/EP2019/061192
申请日：2019-05-02
发明人： CHENGDONG, Ji , MENG, Sheng , YI, Shangchun , YUAN, Caigen
IPC分类号： G01N33/50
摘要： Disclosed is an in-vitro method to determine efficacy of a cosmetic composition or of one or more ingredients comprised therein to inhibit a particulate pollutant from contacting skin, said method comprising the steps of: (i) contacting a human skin equivalent with a cosmetic composition to form, upon drying, a layer thereof extending along mutually perpendicular X and Y and Z axis where along said Z axis said layer is 1 to 100 pm, where said Z axis indicates thickness of said layer; (ii) depositing, on said layer, a known amount of a model fine particulate matter comprising a first substance responsive to depth profile analysis where said cosmetic composition comprises a second substance, not comprised in said model fine particulate matter but also responsive to said depth profile analysis where the response of said first and second substances are distinguishable; (iii) for a pre-determined period after depositing said model fine particulate matter, periodically measuring response of said first and said second substance by said depth profile analysis, to thereby determine the amount of said model fine particulate matter at defined intervals along said Z axis; and, (iv) ascertaining said efficacy based on the amount of said model fine particulate matter at said defined intervals along said Z axis throughout said pre-determined period.
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5.发明申请
公开(公告)号：WO2021254723A1
公开(公告)日：2021-12-23
申请号：PCT/EP2021/063567
申请日：2021-05-21
发明人： WANG, Lin , XU, Bo , YI, Shangchun
摘要： The present invention relates to a personal care composition. In particular, the present invention relates to a personal care composition for blurring benefits. Accordingly, the present invention discloses a personal care composition comprising: a) titanium di-oxide; and b) 8 to 60% by weight of a cross-polymer comprising adipic acid and neopentyl glycol.
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