公开(公告)号：WO2015070036A1

公开(公告)日：2015-05-14

申请号：PCT/US2014064587

申请日：2014-11-07

Applicant: UNIV JOHNS HOPKINS

Inventor： IVKOV ROBERT ,  WOODARD LAUREN ,  POMPER MARTIN G

IPC: A61B18/28 ,  A61B18/04 ,  A61K49/00 ,  A61N2/10 ,  H01F1/06

CPC classification number: A61K49/183 ,  A61B5/0066 ,  A61B5/055 ,  A61B6/032 ,  A61B18/04 ,  A61B18/28 ,  A61B2018/00321 ,  A61B2018/00529 ,  A61F2007/009 ,  A61F2007/0098 ,  A61K9/5094 ,  A61K9/5115 ,  A61K9/5192 ,  A61K41/0052 ,  A61K49/0423 ,  A61K49/0428 ,  A61K49/08 ,  A61N1/406 ,  A61N5/10 ,  H01F1/0054

Abstract: Magnetic iron oxide nanoparticles (MIONs) having silica (SiMION) and gold-silica (AuSiMION) nanoshells, methods of their preparation, and their use in cancer imaging and therapy applications are disclosed.

Abstract translation: 公开了具有二氧化硅（SiMION）和金 - 二氧化硅（AuSiMION）纳米壳的磁性氧化铁纳米颗粒（MION），其制备方法及其在癌症成像和治疗应用中的应用。

公开(公告)号：WO2011050290A3

公开(公告)日：2011-07-28

申请号：PCT/US2010053801

申请日：2010-10-22

Applicant: UNIV JOHNS HOPKINS ,  IVKOV ROBERT ,  KUMAR ANANDA

Inventor： IVKOV ROBERT ,  KUMAR ANANDA

IPC: A61B5/055 ,  A61N2/00 ,  A61N5/00

CPC classification number: A61N2/02 ,  A61B5/055 ,  A61B5/416 ,  A61N1/403 ,  G01R33/422

Abstract: An apparatus for exposing a region of interest of an object, animal or person to an alternating magnetic field has a source of radio-frequency electromagnetic radiation arranged to provide the alternating magnetic field in an exposure volume defined by the apparatus, and a shield arranged between the source of radio-frequency electromagnetic radiation and the exposure volume. The shield includes a material that has a sufficient thickness and arrangement to reduce power deposition to at least regions outside of the region of interest of the object, animal or person during exposure in the exposure volume.

Abstract translation: 用于将物体，动物或人的感兴趣区域暴露于交变磁场的装置具有放射频率电磁辐射源，用于在由装置限定的曝光体积中提供交变磁场，并且屏蔽层布置在 射频电磁辐射源和曝光量。 护罩包括具有足够的厚度和布置的材料，以在曝光量期间曝光期间减少对物体，动物或人的感兴趣区域外的至少区域的功能沉积。