公开(公告)号：WO2012161852A3

公开(公告)日：2013-01-24

申请号：PCT/US2012027911

申请日：2012-03-06

Applicant: UNIV LOMA LINDA MED ,  SCHULTE REINHARD W ,  HURLEY R FORD

Inventor： SCHULTE REINHARD W ,  HURLEY R FORD

IPC: A61B6/03 ,  G12B13/00

CPC classification number: G01T7/005 ,  A61B6/032 ,  A61B6/035 ,  A61B6/4258 ,  A61B6/548 ,  A61B6/583 ,  A61B6/585 ,  G01N23/04 ,  G01N23/046 ,  G01N35/00693 ,  G01N2223/107 ,  G01T1/169 ,  G01T1/2985

Abstract: Disclosed are systems, devices and methodologies related to calibration of an ion based imaging apparatus such as a proton computed tomography scanner. In some implementations, energy degrader plates having known water-equivalent thickness (WET) values can be introduced to an ion beam to introduce different energy degradation settings. Energy detector responses to individual ions subject to such energy degradation settings can be obtained. Such responses can be normalized and correlated to water-equivalent path lengths (WEPL) of the ions based on the known WET values. Such calibration utilizing degrader plates can be performed relatively quickly and can yield accurate WEPL values that facilitate estimation of, for example, a CT image based on relative stopping power of an object.

Abstract translation: 公开了与基于离子的成像装置如质子计算机断层摄影扫描仪的校准相关的系统，装置和方法。 在一些实施方案中，具有已知水当量厚度（WET）值的能量降解板可被引入离子束以引入不同的能量降解设置。 可以获得能量检测器对受到这种能量劣化设置影响的个体离子的响应。 这些响应可以根据已知的WET值被归一化并且与离子的水当量路径长度（WEPL）相关。 利用降解板的这种校准可以相对快速地进行，并且可以产生准确的WEPL值，其有助于基于对象的相对停止功率来估计例如CT图像。