公开(公告)号：WO2022006290A1

公开(公告)日：2022-01-06

申请号：PCT/US2021/039920

申请日：2021-06-30

Applicant: UNIVERSITY OF MISSISSIPPI MEDICAL CENTER

Inventor： ROWLETT, James

IPC: A61K31/4353 ,  A61K31/437 ,  A61P25/30 ,  C07D471/02 ,  C07D471/04 ,  A61K31/501 ,  A61K31/5025 ,  A61K31/53

Abstract: Disclosed are compositions and methods for treating benzodiazepine misuse and/or use disorder. A method of treating benzodiazepine misuse and/or use disorder includes administering to a subject in need thereof of an effective amount of a compound provides both partial modulator and antagonist effects at GABAA receptors.