公开(公告)号：WO2013134649A1

公开(公告)日：2013-09-12

申请号：PCT/US2013/029895

申请日：2013-03-08

申请人： VERASTEM, INC. ,  DERR, Alan, G. ,  WEAVER, David, T. ,  SHAPIRO, Irina ,  PATERSON, Daniel, W. ,  PACHTER, Jonathan, A.

发明人： DERR, Alan, G. ,  WEAVER, David, T. ,  SHAPIRO, Irina ,  PATERSON, Daniel, W. ,  PACHTER, Jonathan, A.

IPC分类号： C12Q1/68 ,  A61K39/395 ,  G01N33/53

CPC分类号： C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/158 ,  G01N33/57484 ,  G01N2800/52

摘要： Novel methods of classifying subjects as candidates for treatment with a cancer associated mesenchymal cell, tumor initiating cancer cell, or cancer stem cell inhibitor treatment and subsequent administration of the cancer associated mesenchymal cell, tumor initiating cancer cell, or cancer stem cell inhibitor are disclosed within.

摘要翻译： 将受试者分类为癌症相关间充质细胞，肿瘤起始癌细胞或癌干细胞抑制剂治疗和随后给予癌症相关间充质细胞，肿瘤起始癌细胞或癌症干细胞抑制剂的候选物的新方法公开在 。

公开(公告)号：WO2013134658A1

公开(公告)日：2013-09-12

申请号：PCT/US2013/029909

申请日：2013-03-08

申请人： VERASTEM, INC.

发明人： WEAVER, David, T. ,  SHAPIRO, Irina ,  PATERSON, Daniel, W. ,  DERR, Alan, G. ,  PACHTER, Jonathan, A.

IPC分类号： C12Q1/68 ,  G01N33/48 ,  G01N33/53

CPC分类号： C12Q1/6886 ,  C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/158 ,  G01N33/574

摘要： Novel methods of classifying subjects as candidates for treatment with agent that inhibits or kills cancer associated mesenchymal cells, tumor initiating cancer cells, or cancer stem cells treatment and subsequent administration of the agent that inhibits or kills cancer associated mesenchymal cells, tumor initiating cancer cells, or cancer stem cells are disclosed within.

摘要翻译： 将受试者分类为用于抑制或杀死癌症相关的间充质细胞，肿瘤起始癌细胞或癌干细胞治疗和随后施用抑制或杀死癌症相关间充质细胞，肿瘤起始癌细胞的试剂的治疗候选物的新方法， 或癌干细胞。