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公开(公告)号:WO1986005202A1
公开(公告)日:1986-09-12
申请号:PCT/US1986000260
申请日:1986-02-06
Applicant: VERAX CORPORATION
Inventor: VERAX CORPORATION , DEAN, Robert, C., Jr. , GRELA, Peter, V. , KARKARE, Subhash, B.
IPC: C12N05/00
CPC classification number: C12P7/06 , C07K14/59 , C12M23/58 , C12M25/20 , C12M27/02 , C12N2531/00 , Y02E50/17
Abstract: A fluidized bed reactor (100) and reaction process, particularly well-suited for culturing cells, for example, for tissue culture and fermentation processes, which involve the treatment of at least a portion of the fluid exiting the fluidized bed reactor (100) in a side loop (160) in a manner to alter its temperature or composition, e.g., oxygenation, with recirculation of this treated fluid to the reactor as a portion of the fluid causing bed fluidization.
Abstract translation: 流化床反应器(100)和反应方法,特别适用于培养细胞,例如用于组织培养和发酵过程,其涉及处理离开流化床反应器(100)的至少一部分流体 一种侧环(160)以改变其温度或组成(例如氧合)的方式,将该处理过的流体再循环到反应器中作为导致床流化的流体的一部分。