公开(公告)号：WO2019043186A1

公开(公告)日：2019-03-07

申请号：PCT/EP2018/073524

申请日：2018-08-31

申请人： VITO NV

发明人： SATYAWALI, Yamini ,  ORMEROD, Dominic ,  MATASSA, Claudia ,  VANBROEKHOVEN, Karolien

IPC分类号： C12P13/00

摘要： The present invention relates to a method for producinga chiral amine, performing a transamination reaction of a prochiral amino acceptor and an amino donor in a first solution in the presence of a transaminase, thereby forming a chiral amine and a co-product in said first solution, characterized in that said amino donor is a high molecular weight (HMW) amino donor, the molecular weight of the HMW amino donor being at least 150 g/mol; or said amino donor is affixed on a support, the total molecular weight of the amino donor and the support being at least 150 g/mol.A device for producing and separating a chiral amine is provided as well.

公开(公告)号：WO2017103163A1

公开(公告)日：2017-06-22

申请号：PCT/EP2016/081516

申请日：2016-12-16

申请人： VITO NV

发明人： SATYAWALI, Yamini ,  ORMEROD, Dominic ,  VANBROEKHOVEN, Karolien ,  BUEKENHOUDT, Anita

IPC分类号： C07C209/86 ,  C12P13/00 ,  C07C211/27 ,  C07C211/06 ,  B01D61/24

CPC分类号： C07C209/86 ,  B01D61/246 ,  B01D69/02 ,  B01D69/144 ,  B01D71/02 ,  B01D2323/04 ,  B01D2323/36 ,  B01D2325/38 ,  C12P13/001 ,  C07C211/27 ,  C07C211/06

摘要： The present invention provides an improved membrane based process to separate amines or organic acids from a solution comprising at least one amine or at least one organic acid, respectively, according to their hydrophobic properties. In particular, in the methods described herein the (more hydrophobic) amine or organic acid passes the hydrophobic membrane into an acidic aqueous solution, thus selectively removing the amine or organic acid from the first solution. The methods are particularly suitable to obtain chiral amines in high yield, wherein a transaminase catalysed transamination of an amino donor and amino acceptor is combined with a hydrophobic membrane separation of the produced chiral amine, wherein the selective removal of the chiral amine from the reaction mixture promotes the further transformation of the amino acceptor into the product chiral amine.

摘要翻译： 本发明提供了一种改进的基于膜的方法，用于根据它们的疏水性分别从包含至少一种胺或至少一种有机酸的溶液中分离胺或有机酸。 特别地，在本文所述的方法中，（疏水性更强的）胺或有机酸将疏水性膜通入酸性水溶液中，从而有选择地从第一溶液中除去胺或有机酸。 该方法特别适用于以高产率获得手性胺，其中氨基供体和氨基受体的转氨酶催化的转氨基与所产生的手性胺的疏水性膜分离相结合，其中从反应混合物中选择性地除去手性胺 促进氨基受体进一步转化为产物手性胺。

公开(公告)号：WO2021121889A1

公开(公告)日：2021-06-24

申请号：PCT/EP2020/083404

申请日：2020-11-25

申请人： VITO NV

发明人： VAN HECKE, Wouter ,  VENDAMME, Richard ,  VANBROEKHOVEN, Karolien ,  ORTIZ, Pablo

IPC分类号： C08F220/20 ,  C08F120/18

摘要： The present invention relates to stabilizing monomers obtained from mono(meth)acrylated monolignols providing AA (antioxidant activity) to copolymers, and obtained copolymers thereof. It further provides methods for preparing such copolymers, the building blocks and the use thereof in the manufacture of copolymers comprising said stabilizing monomers obtained from mono(meth)acrylated monolignols providing AA. In a further aspect, this invention elaborates on the possible applications of the polymers thus obtained.

公开(公告)号：WO2020136211A1

公开(公告)日：2020-07-02

申请号：PCT/EP2019/087031

申请日：2019-12-24

申请人： VITO NV

发明人： BOUWMAN, Lambertus ,  PANT, Deepak ,  BULUT, Metin ,  VANBROEKHOVEN, Karolien

IPC分类号： B01D53/14 ,  B01D53/73 ,  B01D53/96

摘要： The present invention is related to a method and related device (10) for capturing carbon dioxide and converting the captured carbon dioxide to a chemical compound. In particular, the present invention is related to a method for capturing a carbon dioxide gas by contacting it with a liquid alkaline solution, which reacts with the carbon dioxide and converts it into (bi)carbonate, and including a further processing step to electrochemically convert the (bi)carbonate to an economically valuable chemical compound.

公开(公告)号：WO2019068488A1

公开(公告)日：2019-04-11

申请号：PCT/EP2018/075646

申请日：2018-09-21

申请人： VITO NV

发明人： BOUWMAN, Lambertus ,  VAN HOUTVEN, Diana ,  PANT, Deepak ,  ALVAREZ GALLEGO, Yolanda ,  VANBROEKHOVEN, Karolien

IPC分类号： H01M4/86 ,  H01M4/96

CPC分类号： H01M4/86 ,  H01M4/8626 ,  H01M4/96

摘要： The present invention relates to a carbon based electrode with a large geometrical surface area comprising a frame of an electrically conductive material with several cut-outs with a surface area, which cut-outs are separated from each other by portions of the conductive material, wherein carbon based sub-electrodes dimensioned so as to a least cover the surface area of the cut-outs are positioned in the cut-outs and conductively connected to at least part of each of the portions of the conductive material adjacent to the carbon based sub-electrodes.

公开(公告)号：WO2019048438A1

公开(公告)日：2019-03-14

申请号：PCT/EP2018/073782

申请日：2018-09-04

申请人： VITO NV

发明人： VAN HECKE, Wouter ,  ELSLANDER, Helmut ,  VANBROEKHOVEN, Karolien ,  DE WEVER, Helene ,  BECKERS, Herman

IPC分类号： C12P7/06 ,  C12M1/107 ,  C12P7/16 ,  C12P7/28 ,  C12P7/62 ,  C12P7/64 ,  C12P13/02

摘要： Method of obtaining a compound and corresponding apparatus. The method comprises adding a substrate (14) to a medium (132) comprised in a reactor (13, 33), and reacting the substrate in the reactor to form the compound. A first stream (15) is separated from the reaction liquid through a first membrane (115). A second stream (16) is separated from the reaction liquid through a second membrane (125).The first membrane is a filtration membrane and the second membrane is configured for liquid-gas or liquid-liquid extraction The first membrane and the second membrane are at least partially immersed in the medium and are moved relative to the reactor during the separation steps.