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公开(公告)号:WO1996041987A2
公开(公告)日:1996-12-27
申请号:PCT/US1996008424
申请日:1996-06-03
Applicant: WAYNE STATE UNIVERSITY
Inventor: WAYNE STATE UNIVERSITY , SPEARS, James, R.
IPC: F17C00/00
CPC classification number: A23L2/54 , A61K9/5089 , A61M1/1678 , A61M1/169 , A61M1/1698 , A61M1/32 , A61M25/0026 , A61M25/007 , A61M25/09 , A61M2025/0057 , A61M2202/0476 , B01F3/04439 , B01J13/04 , C01B5/00 , C01B13/00 , C01B13/02 , D21C9/147 , Y10S261/28 , A61M2202/0007
Abstract: An apparatus (10) and method for delivering a high partial pressure of a gas into a liquid. The apparatus has a gas transfer device (12) with a housing (14) that includes upstream (16) and downstream regions, between which there is located a gas-liquid contacting region (20) with contacting members (22), such as hollow microporous fibers. A reservoir (36) of gas supplies the gas at a high pressure (P) to a flask (38) of gas-depleted liquid and to the gas transfer device (12). The reservoir (36) of gas provides hydrostatic pressure for urging the liquid through the contacting members (22) and propelling the gas around the contacting members (32) so that the gas does not diffuse across the contacting members (22). The gas-enriched liquid is then ducted to a high resistance delivery channel (44) for administration to a site of interest without effervescence, bubble formation, or significant disruption of laminar flow.
Abstract translation: 一种用于将气体的高分压输送到液体中的装置(10)和方法。 该装置具有气体输送装置(12),其具有包括上游(16)和下游区域的壳体(14),在所述壳体(14)之间位于具有接触构件(22)的气液接触区域(20) 微孔纤维。 气体的储存器(36)将高压(P)的气体供应到气体耗尽液体的烧瓶(38)和气体输送装置(12)。 气体的储存器(36)提供静水压力,用于通过接触构件推动液体并推动气体围绕接触构件(32),使得气体不会扩散通过接触构件(22)。 然后将富含气体的液体导管到高阻力输送通道(44),用于施用于感兴趣的部位,而不发生泡腾,气泡形成或层流的显着破坏。
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2.
公开(公告)号:WO1996040334A1
公开(公告)日:1996-12-19
申请号:PCT/US1996008083
申请日:1996-06-03
Applicant: WAYNE STATE UNIVERSITY
Inventor: WAYNE STATE UNIVERSITY , SPEARS, James, R. , CRILLY, Richard, J.
IPC: A61M15/00
CPC classification number: A23L2/54 , A61K9/5089 , A61M1/1678 , A61M1/1698 , A61M1/32 , A61M1/3613 , A61M25/0026 , A61M25/007 , A61M25/09 , A61M2025/0057 , A61M2202/0476 , B01F3/04099 , B01F3/04439 , B01F3/04985 , B01F3/0876 , B01F2003/04879 , B01F2003/04893 , B01F2215/0034 , B01F2215/0052 , B01F2215/0075 , B01F2215/0078 , B01J13/04 , C01B5/00 , C01B13/00 , C01B13/02 , D21C9/147 , A61M2202/0007
Abstract: An apparatus (10) and method for delivering an oxygen-supersaturated physiologic solution (12) into a lumen (14) of a blood vessel (16) to replace arterial blood beyond an angioplasty catheter (22) during clinical angioplasty without bubble formation.
Abstract translation: 一种用于在临床血管成形术期间将氧过饱和生理溶液(12)输送到血管(16)的腔(14)中以替代血管成形术导管(22)以外的动脉血而不产生气泡的装置(10)和方法。
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