公开(公告)号：WO2005110231A1

公开(公告)日：2005-11-24

申请号：PCT/US2005/015430

申请日：2005-05-04

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION ,  MISTRETTA, Charles Anthony ,  ROWLEY, Howard Andrew ,  VAN LYSEL, Michael, Scott ,  CHEN, Guang-Hong

Inventor： MISTRETTA, Charles Anthony ,  ROWLEY, Howard Andrew ,  VAN LYSEL, Michael, Scott ,  CHEN, Guang-Hong

IPC: A61B6/02

CPC classification number: A61B6/025 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/504 ,  A61B6/507

Abstract: An x-ray system for use with image-guided medical procedures is programmed to move in a first scan path to acquire cone beam attenuation data from which a three-dimensional digital subtraction angiogram of selected vasculature is reconstructed. The x-ray system is also programmed to move in a second scan path to acquire a series of tomosynthesis images during the inflow of a contrast agent into the selected vasculature. Parametric images are produced from information in the tomosynthesis images which indicate blood perfusion physiology of the tissues served by the vasculature.

Abstract translation: 用于图像引导医疗程序的X射线系统被编程为在第一扫描路径中移动以获取锥形束衰减数据，重建所选择的脉管系统的三维数字减影血管造影图。 X射线系统还被编程为在第二扫描路径中移动以在造影剂流入所选择的脉管系统期间获取一系列的断层合成图像。 参数化图像是从表示血管系统服务的组织的血液灌注生理学的断层合成图像中的信息产生的。

公开(公告)号：WO2005076775A3

公开(公告)日：2005-08-25

申请号：PCT/US2004/027679

申请日：2004-08-26

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION ,  CHEN, Guang-Hong

Inventor： CHEN, Guang-Hong

IPC: G06T11/00 ,  A61B6/00

Abstract: A new image reconstruction method is described for CT systems. Reconstruction formulas for general application to any CT system geometry are derived and more specific formulas for two third generation CT system geometries are described. A preferred embodiment of a CT system which employs one of the specific formulas is described.

公开(公告)号：WO2017132455A1

公开(公告)日：2017-08-03

申请号：PCT/US2017/015254

申请日：2017-01-27

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION

Inventor： CHEN, Guang-Hong

IPC: G06T11/00

CPC classification number: G06T11/008 ,  G06T11/006 ,  G06T2211/412 ,  G06T2211/421 ,  G06T2211/424 ,  G06T2211/436

Abstract: Described here is a system and method for image reconstruction that can automatically and iteratively produce multiple images from one set of acquired data, in which each of these multiple images corresponds to a subset of the acquired data that is self-consistent, but inconsistent with other subsets of the acquired data. The image reconstruction includes iteratively minimizing the rank of an image matrix whose columns each correspond to a different image, and in which one column corresponds to a user-provided prior image of the subject. The rank minimization is constrained subject to a consistency condition that enforces consistency between the forward projection of each column in the image matrix and a respective subset of the acquired data that contains data that is consistent with data in the subset, but inconsistent with data not in the subset.

Abstract translation: 这里描述的是一种用于图像重建的系统和方法，其可以自动且迭代地从一组采集的数据中产生多个图像，其中这些多个图像中的每一个对应于采集的数据的子集， 自洽，但与所获得数据的其他子集不一致。 图像重建包括迭代地最小化其图像矩阵的秩，每个图像矩阵的列对应于不同的图像，并且其中一列对应于对象的用户提供的先前图像。 秩最小化受到一致性条件的约束，所述一致性条件强制图像矩阵中每列的正向投影与所获取数据的相应子集之间的一致性，所述子集包含与子集中的数据一致但与不在 子集。

公开(公告)号：WO2010062956A1

公开(公告)日：2010-06-03

申请号：PCT/US2009/065920

申请日：2009-11-25

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION ,  CHEN, Guang-Hong ,  TANG, Jie

Inventor： CHEN, Guang-Hong ,  TANG, Jie

IPC: A61B6/03 ,  G06T11/00

CPC classification number: A61B6/032 ,  A61B5/7289 ,  A61B5/7292 ,  A61B6/4441 ,  A61B6/488 ,  A61B6/503 ,  G06T11/006 ,  G06T2211/412 ,  G06T2211/424 ,  G06T2211/432

Abstract: An image reconstruction method for cardiac cone beam CT is provided, in which data acquired as truncated projections using current cardiac flat panel detectors is reconstructed to form a high quality image of a desired cardiac phase. An iterative method is utilized to reconstruct a prior image from all of the acquired truncated data without cardiac gating. Subsequently, a reconstruction method, in which the prior image is utilized in a prior image constrained reconstruction method, is utilized to reconstruct images for each individual cardiac phase. The objective function in such a prior image constrained reconstruction method is modified to incorporate the conditions used in the production of the prior image so that the data truncation problem is properly addressed.

Abstract translation: 提供了一种用于心脏锥形束CT的图像重建方法，其中重建使用当前心脏平板检测器作为截短投影获得的数据，以形成所需心脏相的高质量图像。 利用迭代方法从没有心脏门控的所有获取的截断数据重建先前图像。 随后，利用现有图像在先前图像约束重建方法中使用的重建方法来重建每个单独心脏相位的图像。 这种现有图像约束重建方法中的目标函数被修改为包含在生成现有图像中使用的条件，以便适当地解决数据截断问题。

公开(公告)号：WO2005010824A1

公开(公告)日：2005-02-03

申请号：PCT/US2004/018769

申请日：2004-06-15

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION ,  CHEN, Guang-Hong ,  MISTRETTA, Charles, A.

Inventor： CHEN, Guang-Hong ,  MISTRETTA, Charles, A.

IPC: G06T11/00

CPC classification number: G06T11/006 ,  G06T2211/412 ,  G06T2211/421 ,  Y10S378/901

Abstract: A generalized projection-slice theorem for divergent beam projections is disclosed. The theorem results in a method for processing the Fourier transform of the divergent beam projections at each view acquired by a CT system to the Fourier transform of the object function. Using this method, an inverse Fourier transform may be used to reconstruct tomographic images from the acquired divergent beam projections.

Abstract translation: 公开了一种用于发散光束投影的广义投影切片定理。 该定理产生用于处理由CT系统获取的每个视图上的发散光束投影的傅里叶变换到目标函数的傅里叶变换的方法。 使用该方法，可以使用逆傅里叶变换来从所获取的发散束投影重建断层图像。

公开(公告)号：WO2023076504A1

公开(公告)日：2023-05-04

申请号：PCT/US2022/048072

申请日：2022-10-27

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION

Inventor： CHEN, Guang-Hong ,  LI, Ke

IPC: A61B6/03 ,  A61B6/00

Abstract: A system and method for creating computed tomography (CT) images includes acquiring or accessing sinogram data and determining a photon count for the sinogram data. The method includes generating unbiased sinogram data from the sinogram data using an unbiased estimator and the photon count and reconstructing a CT image from the unbiased sinogram data.

公开(公告)号：WO2009082736A1

公开(公告)日：2009-07-02

申请号：PCT/US2008/088010

申请日：2008-12-22

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION ,  SAMSONOV, Alexey, A. ,  CHEN, Guang-Hong ,  WU, Huimin ,  BLOCK, Walter, F.

Inventor： SAMSONOV, Alexey, A. ,  CHEN, Guang-Hong ,  WU, Huimin ,  BLOCK, Walter, F.

IPC: G06T11/00

CPC classification number: G06T11/006 ,  A61B6/037 ,  G06T2211/412 ,  G06T2211/424

Abstract: An image reconstruction method applicable to a number of different imaging modalities including magnetic resonance imaging (MRI), x-ray computed tomography (CT), positron emission tomography (PET), and single photon emission computed tomography (SPECT) is disclosed. A sparsifying image is reconstructed from a series of acquired undersampled data to provide a priori knowledge of a subject being imaged. An iterative reconstruction process is further employed to iteratively determine a correction image for a given image frame that, when subtracted from the sparsifying image, produces a quality image for the image frame.

Abstract translation: 公开了适用于包括磁共振成像（MRI），X射线计算机断层摄影（CT），正电子发射断层扫描（PET）和单光子发射计算机断层摄影（SPECT）在内的许多不同成像方式的图像重建方法。 从一系列获取的欠采样数据重建稀疏图像，以提供被成像对象的先验知识。 进一步采用迭代重建处理来迭代地确定给定图像帧的校正图像，当从稀疏图像中减去时，该图像帧产生用于图像帧的质量图像。

公开(公告)号：WO2006058124A1

公开(公告)日：2006-06-01

申请号：PCT/US2005/042546

申请日：2005-11-22

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION ,  CHEN, Guang-Hong

Inventor： CHEN, Guang-Hong

IPC: G06T11/00

CPC classification number: G06T11/006 ,  A61B6/027 ,  G06T2211/416 ,  G06T2211/421

Abstract: A tomographic image reconstruction method produces either 2D or 3D images from fan beam or cone beam projection data by filtering the backprojection image of differentiated projection data. The reconstruction is mathematically exact if sufficient projection data is acquired. A cone beam embodiment and both a symmetric and asymmetric fan beam embodiment are described.

Abstract translation: 断层图像重建方法通过对差分投影数据的反投影图像进行滤波来产生来自扇形束或锥形束投影数据的2D或3D图像。 如果获取足够的投影数据，则重构在数学上是准确的。 描述锥形束实施例以及对称和非对称扇形束实施例。

公开(公告)号：WO2014159029A1

公开(公告)日：2014-10-02

申请号：PCT/US2014/021581

申请日：2014-03-07

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION

Inventor： CHEN, Guang-Hong

IPC: G06T11/00

CPC classification number: G06T11/003 ,  G06T11/006 ,  G06T2211/412 ,  G06T2211/424

Abstract: Described here is a system and method for image reconstruction that can automatically and iteratively produce multiple images from one set of acquired data, in which each of these multiple images corresponds to a subset of the acquired data that is self-consistent, but inconsistent with other subsets of the acquired data. The image reconstruction includes iteratively minimizing the rank of an image matrix whose columns each correspond to a different image. The rank minimization is constrained subject to a consistency condition that enforces consistency between the forward projection of each column in the image matrix and a respective subset of the acquired data that contains data that is consistent with data in the subset, but inconsistent with data not in the subset.

Abstract translation: 这里描述了一种用于图像重建的系统和方法，其可以从一组获取的数据自动和迭代地产生多个图像，其中这些多个图像中的每一个对应于所获取的数据的子集，其是自相矛盾的，但与其他的不一致 获取的数据的子集。 图像重建包括迭代地最小化其列各自对应于不同图像的图像矩阵的等级。 排序最小化受制于一致性条件，强制图像矩阵中每列的前向投影与包含与该子集中的数据一致的数据的所获取数据的相应子集之间的一致性，但与不在 该子集。

公开(公告)号：WO2011146153A1

公开(公告)日：2011-11-24

申请号：PCT/US2011/023570

申请日：2011-02-03

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION ,  CHEN, Guang-Hong ,  TANG, Jie ,  NETT, Brian

Inventor： CHEN, Guang-Hong ,  TANG, Jie ,  NETT, Brian

IPC: G06T11/00

CPC classification number: G06T11/006 ,  G06T2211/424

Abstract: A method for reconstructing an image of a subject with a medical imaging system is provided. Image data is acquired with the medical imaging system, typically in an undersampled manner. A prior image constrained compressed sensing (PICCS] image reconstruction method is then implemented to reconstruct images of the subject being imaged. The prior image used in such a method is produced from so-called averaged image data. The averaged image data is produced by effectively averaging signal information associated with a plurality of different slice locations along a direction orthogonal to the plane parallel to the slice locations. Weightings are calculated from images reconstructed in a conventional manner from the acquired image data, and these weightings are employed to produce the averaged image data. By producing a prior image in this manner, a higher signal-to-noise ratio is achievable, allowing trade¬ offs with factors such as radiation dose in x-ray imaging.

Abstract translation: 提供了一种用于用医学成像系统重建对象的图像的方法。 用医学成像系统获取图像数据，通常以欠采样的方式。 然后实现先前图像约束压缩感知（PICCS）图像重建方法以重建被成像的对象的图像。在这种方法中使用的先前图像由所谓的平均图像数据产生，平均图像数据通过有效地产生 将平均信号信息与沿与平行于切片位置的平面正交的方向与多个不同切片位置相关联的信号信息，根据所获取的图像数据以常规方式重建的图像计算加权，并且使用这些加权来产生平均图像 通过以这种方式产生先前的图像，可以实现更高的信噪比，从而能够与诸如X射线成像中的辐射剂量的因素进行折衷。