公开(公告)号：WO2019135676A1

公开(公告)日：2019-07-11

申请号：PCT/NL2018/050893

申请日：2018-12-31

申请人： TECHNISCHE UNIVERSITEIT DELFT

发明人： BROWN, Jeremy Michael Cooney ,  SCHAART, Dennis Robert

IPC分类号： A61B6/06 ,  A61B6/00 ,  G21K1/02 ,  A61B6/03

CPC分类号： A61B6/4258 ,  A61B6/037 ,  A61B6/06 ,  A61B6/4417 ,  G01T1/1648 ,  G21K1/02

摘要： The invention provides an active collimator system (100) having a coded collimator aperture (111), the active collimator system (100) comprising scintillator bars (110) and photosensor units (130), wherein the scintillator bars (110) are configured to absorb incoming gamma rays (160) and scintillate, thereby emitting scintillation photons (161), wherein the scintillator bars (110) are further configured to define the coded collimator aperture (111), wherein the photosensor units (130) are configured to detect the scintillation photons (161), and wherein the photosensor units (130) are directed to scintillator bar ends (112) of the scintillator bars (110).

公开(公告)号：WO2019000401A1

公开(公告)日：2019-01-03

申请号：PCT/CN2017/091118

申请日：2017-06-30

申请人： SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

发明人： LIU, Weiping ,  GU, Xiaoyue ,  CHEN, Jianqiao ,  LI, Hongdi

IPC分类号： A61B6/03

CPC分类号： A61B6/4258 ,  A61B6/032 ,  A61B6/037 ,  A61B6/4266 ,  A61B6/4275 ,  A61B6/4411 ,  A61B6/4417 ,  G01T1/2018 ,  G01T1/2985

摘要： The present disclosure relates to a system for imaging. The system may include a supporting assembly and a detector assembly. The supporting assembly may include a detection region to accommodate a subject. The detector assembly may surround the detection region. The detector assembly may be configured to detect radiation rays emitted from the subject located within the detection region. The detector assembly may include a plurality of detector rings. Each detector ring may include a scintillator array and a plurality of photosensors. The plurality of detector rings may be arranged on the supporting assembly in an axial direction of the supporting assembly to form an axial field of view (FOV) having a length no less than 0.75 meters.

公开(公告)号：WO2018227449A1

公开(公告)日：2018-12-20

申请号：PCT/CN2017/088375

申请日：2017-06-15

申请人： SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

发明人： QUAN, Guotao

IPC分类号： A61B6/04 ,  G06T7/00

CPC分类号： A61B6/545 ,  A61B6/032 ,  A61B6/037 ,  A61B6/0407 ,  A61B6/5205 ,  A61B6/563 ,  G06F19/321 ,  G06T7/0012 ,  G06T7/70 ,  G06T2207/10081 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30004 ,  G16H30/20 ,  G16H40/63 ,  G16H50/20 ,  G16H50/50

摘要： The present disclosure relates to a method, system and non-transitory computer readable medium. In some embodiments, the method includes: acquiring image data of a target subject positioned on a scanning table; determining, by a processor, first position information of the target subject based on the image data; determining, by the processor, second position information related to a scan region of the target subject based on the image data; and scanning, using an imaging device, the target subject based on the first position information and the second position information.

公开(公告)号：WO2018178148A1

公开(公告)日：2018-10-04

申请号：PCT/EP2018/057912

申请日：2018-03-28

申请人： KONINKLIJKE PHILIPS N.V.

发明人： UHLEMANN, Falk

IPC分类号： A61B5/00 ,  G09B9/00 ,  A61B6/00 ,  A61B5/055 ,  G01R33/54 ,  G06F19/00

CPC分类号： A61B5/0033 ,  A61B5/055 ,  A61B5/6803 ,  A61B5/742 ,  A61B6/032 ,  A61B6/037 ,  A61B6/466 ,  A61B6/488 ,  A61B6/5264 ,  A61B2560/0223 ,  G01R33/283 ,  G01R33/543 ,  G01R33/5673 ,  G16H30/20 ,  G16H40/63 ,  G16H50/50

摘要： The present disclosure relates to a method for planning an imaging scan protocol to be performed by a scanning imaging system (100), the method comprising simulating for a patient (118) by a virtual reality system (200) an imaging scan, the imaging scan following a chosen imaging scan protocol (141), recording physiological data (152) of the patient (118) generated in response to the simulating and modifying the chosen imaging scan protocol (141) based on the physiological data (152).

公开(公告)号：WO2018082549A1

公开(公告)日：2018-05-11

申请号：PCT/CN2017/108649

申请日：2017-10-31

申请人： SHENZHEN UNITED IMAGING HEALTHCARE CO., LTD.

发明人： YANG, Gang ,  DU, Miaoyan

IPC分类号： A61B6/03 ,  G06T7/00

CPC分类号： G06T7/337 ,  A61B5/0035 ,  A61B5/055 ,  A61B5/7425 ,  A61B5/743 ,  A61B6/035 ,  A61B6/037 ,  A61B6/5235 ,  A61B6/5247 ,  G06T3/0068 ,  G06T3/20 ,  G06T3/60 ,  G06T7/50 ,  G06T7/74 ,  G06T11/006 ,  G06T11/008 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10104 ,  G06T2211/421 ,  G06T2211/424

摘要： The present disclosure relates to a method and system for registering multi-modality images. The method may include: acquiring a first image relating to a registration model, wherein the registration model includes a plurality of reference objects; acquiring a second image relating to the registration model; determining a set of reference points based on the plurality of reference objects; determining a set of mapping data corresponding to the set of reference points in the first image and the second image; and determining one or more registration parameters based on the set of mapping data.

摘要翻译： 本公开涉及用于配准多模态图像的方法和系统。 该方法可以包括：获取与配准模型有关的第一图像，其中配准模型包括多个参考对象; 获取与所述配准模型相关的第二图像; 基于所述多个参考对象确定一组参考点; 确定与所述第一图像和所述第二图像中的所述一组参考点相对应的一组映射数据; 以及基于该组映射数据确定一个或多个注册参数。

公开(公告)号：WO2018048882A1

公开(公告)日：2018-03-15

申请号：PCT/US2017/050248

申请日：2017-09-06

申请人： THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK

发明人： TONGE, Peter ,  ZHANG, Zhuo ,  SMITH-JONES, Peter ,  LIU, Li ,  WANG, Hui

IPC分类号： A61K51/00 ,  C07B35/02 ,  C07B39/00 ,  C07C229/60

CPC分类号： A61B6/037 ,  A61K51/0402 ,  A61P31/04 ,  C07B59/001 ,  C07C227/12 ,  C07C229/60

摘要： The present invention provides a composition comprising the compound having the structure: Formula or a salt of the compound; 4-amino-2- [ 19 F] -fluorobenzoic acid or a salt of 4-amino-2- [ 19 F] -fluorobenzoic acid; and at least one acceptable carrier.

摘要翻译： 本发明提供了包含具有以下结构的化合物的组合物：所述化合物或所述化合物的盐; 4-氨基-2- [19 F] - 氟苯甲酸或4-氨基-2- [19 F] - 氟苯甲酸的盐; 和至少一个可接受的载体。

公开(公告)号：WO2018045274A1

公开(公告)日：2018-03-08

申请号：PCT/US2017/049832

申请日：2017-09-01

申请人： THE GENERAL HOSPITAL CORPORATION

发明人： ROSEN, Matthew, S. ,  ZHU, Bo ,  ROSEN, Bruce, R.

IPC分类号： G06N3/02 ,  G01R33/12 ,  G01R33/20 ,  G06K9/36

CPC分类号： G06T11/006 ,  A61B5/0035 ,  A61B5/0059 ,  A61B5/055 ,  A61B5/7267 ,  A61B5/7425 ,  A61B6/032 ,  A61B6/037 ,  A61B6/463 ,  A61B6/5247 ,  A61B8/463 ,  A61B8/5261 ,  G01R33/12 ,  G01R33/4818 ,  G01R33/4824 ,  G01R33/5608 ,  G06K9/623 ,  G06K9/6274 ,  G06K2209/05 ,  G06N3/0454 ,  G06N3/08 ,  G06T2210/41 ,  G16H30/40

摘要： A system may transform sensor data from a sensor domain to an image domain using data-driven manifold learning techniques which may, for example, be implemented using neural networks. The sensor data may be generated by an image sensor, which may be part of an imaging system. Fully connected layers of a neural network in the system may be applied to the sensor data to apply an activation function to the sensor data. The activation function may be a hyperbolic tangent activation function. Convolutional layers may then be applied that convolve the output of the fully connected layers for high level feature extraction. An output layer may be applied to the output of the convolutional layers to deconvolve the output and produce image data in the image domain.

摘要翻译： 系统可以使用数据驱动的流形学习技术将传感器数据从传感器域转换到图像域，所述数据驱动的流形学习技术例如可以使用神经网络来实现。 传感器数据可以由图像传感器产生，该图像传感器可以是成像系统的一部分。 系统中神经网络的完全连接层可以应用于传感器数据以将激活功能应用于传感器数据。 激活函数可以是双曲正切激活函数。 然后可以应用卷积层来卷积完全连接的层的输出以进行高级特征提取。 可以将输出层应用于卷积层的输出以对输出解卷积并在图像域中产生图像数据。

公开(公告)号：WO2018044577A1

公开(公告)日：2018-03-08

申请号：PCT/US2017/047325

申请日：2017-08-17

申请人： GENERAL ELECTRIC COMPANY

发明人： HEFETZ, Yaron ,  KHAMAISI, Raed

IPC分类号： A61B6/03 ,  G01T1/24 ,  A61B6/00

CPC分类号： G01T7/00 ,  A61B6/035 ,  A61B6/037 ,  A61B6/4488 ,  G01T1/161 ,  G01T1/244 ,  H05K7/20245 ,  H05K7/2039

摘要： An imaging system is provided that includes a gantry, plural radiation detector head assemblies, a cooling unit, and a manifold. The radiation detector head assemblies are disposed about a bore of the gantry. Each radiation detector head assembly includes a detector housing and a rotor assembly. The rotor assembly is configured to be rotated about an axis. The rotor assembly includes a detector unit that in turn includes an absorption member and associated processing circuitry. The cooling unit is mounted to the gantry and is configured to provide an output flow of air at a controlled temperature. The manifold is coupled to the cooling unit and the plural radiation detector head assemblies, and places the cooling unit and radiation detector head assemblies in fluid communication with each other. The output flow of air from the cooling unit is delivered to the plural radiation detector head assemblies.

摘要翻译： 提供了一种成像系统，其包括机架，多个辐射探测器头组件，冷却单元和歧管。 辐射探测器头组件围绕机架的孔布置。 每个辐射检测器头组件包括检测器壳体和转子组件。 转子组件构造成绕轴线旋转。 转子组件包括检测器单元，该检测器单元又包括吸收构件和相关的处理电路。 冷却单元安装在门架上，并被配置为提供受控温度下的输出空气流。 歧管联接到冷却单元和多个辐射检测器头组件，并且使冷却单元和辐射检测器头组件彼此流体连通。 来自冷却单元的输出空气流被输送到多个辐射探测器头组件。

公开(公告)号：WO2017140133A1

公开(公告)日：2017-08-24

申请号：PCT/CN2016/105361

申请日：2016-11-10

申请人： SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

发明人： MA, Runxia ,  WANG, Lei

IPC分类号： A61B6/03

CPC分类号： A61B6/03 ,  A61B6/037 ,  A61B6/0407 ,  A61B6/0457 ,  A61B6/467 ,  A61B6/468 ,  A61B6/5205 ,  A61B6/54 ,  A61B6/545 ,  G06F19/00 ,  G06F19/321

摘要： A system (100) and a method for medical imaging are provided. An imaging device having a table may be provided. Scans of a subject located on the table at multiple table positions may be performed based on a scanning protocol, each scan covering a portion of the subject. Data may be acquired based on the scans of the subject. An image may be reconstructed based on the acquired data.

摘要翻译： 提供了一种用于医学成像的系统（100）和方法。 可以提供具有桌子的成像装置。 可以基于扫描协议对位于桌子上的多个桌位置处的对象进行扫描，每次扫描覆盖对象的一部分。 可以基于对象的扫描来获取数据。 根据采集的数据可以重建图像。

公开(公告)号：WO2017136700A1

公开(公告)日：2017-08-10

申请号：PCT/US2017/016473

申请日：2017-02-03

申请人： THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA ,  SIDRA MEDICAL AND RESEARCH CENTER

发明人： MARINCOLA, Francesco, M. ,  REDDY, Ravinder ,  HARIS, Mohammad ,  HARIHARAN, Hari ,  BAGGA, Puneet ,  SCHNALL, Mitchell, D.

IPC分类号： A23L27/30 ,  A61B5/055 ,  A61B6/03 ,  A61K49/06 ,  A61K49/10

CPC分类号： A61K51/0421 ,  A61B5/055 ,  A61B6/037 ,  A61K49/108 ,  A61K51/0491

摘要： The present disclosure relates to magnetic resonance imaging (MRI) methods comprising (i) obtaining a baseline chemical exchange saturation transfer (CEST) MRI image of a patient, (ii) administering an effective amount of a non-nutritive sweetener to the patient, and (iii) obtaining one or more test CEST MRI image of the patient subsequent to the administering step (ii); wherein the step (i) and (iii) acquisition parameters are substantially the same. The non- nutritive sweetener may include a natural or artificial sugar alcohol, polyol, or combinations or derivatives thereof.

摘要翻译： 本公开涉及磁共振成像（MRI）方法，其包括（i）获得患者的基线化学交换饱和转移（CEST）MRI图像，（ii）施用有效量的非 （iii）在所述施用步骤（ii）之后获得所述患者的一个或多个测试CEST MRI图像;以及（iii）在所述施用步骤（ii）之后获得所述患者的一个或多个测试CEST MRI图像。 其中步骤（i）和（iii）采集参数基本相同。 非营养甜味剂可以包括天然或人造糖醇，多元醇或其组合或衍生物。