X-RAY BIOPSY SPECIMEN IMAGER AND METHODS
    2.
    发明申请
    X-RAY BIOPSY SPECIMEN IMAGER AND METHODS 审中-公开
    X射线活检标本成像仪和方法

    公开(公告)号:WO2017200801A1

    公开(公告)日:2017-11-23

    申请号:PCT/US2017/031740

    申请日:2017-05-09

    申请人: LI-COR, INC.

    发明人: WANG, Han-Wei

    摘要: Methods and devices are disclosed for the tomographic imaging of a biological sample from almost all rotational perspectives in three-dimensional space and with multiple imaging modalities. A biological sample is positioned on an imaging stage that is capable of nearly full 360-degree rotation in at least one of two substantially orthogonal axes. Positioned about the stage is an X-ray imaging module enabling the recording of a series of images. A reflected light imaging module can also be positioned about the stage to enable recording of black and white or color white light images. A computer can use the images to construct three-dimensional models of the sample and to render images of the sample conveying information from one or more imaging channels.

    摘要翻译: 公开了用于来自三维空间中的几乎所有旋转视角和具有多个成像模态的生物样品的层析成像的方法和设备。 生物样品位于成像台上,该成像台能够在两个基本上正交的轴中的至少一个中几乎完全360度旋转。 定位在舞台上的是一个X射线成像模块,可以记录一系列图像。 反射光成像模块也可以放置在舞台的周围,以便记录黑白或彩色白光图像。 计算机可以使用这些图像来构建样本的三维模型并且呈现来自一个或多个成像通道的样本的图像传输信息。

    TOMOGRAPHY APPARATUS AND METHOD FOR RECONSTRUCTING TOMOGRAPHY IMAGE THEREOF
    3.
    发明申请
    TOMOGRAPHY APPARATUS AND METHOD FOR RECONSTRUCTING TOMOGRAPHY IMAGE THEREOF 审中-公开
    用于重建其层析图像的层析摄影装置和方法

    公开(公告)号:WO2017126772A1

    公开(公告)日:2017-07-27

    申请号:PCT/KR2016/010876

    申请日:2016-09-29

    IPC分类号: A61B6/00 A61B6/03

    摘要: A tomography method for generating a computed tomography (CT) image, including generating a first tomography image based on first raw data corresponding to a received X-ray comprising acquired photons; determining second raw data by generating a second tomography image having an increased resolution in comparison with the first tomography image and performing forward projection on the second tomography image; determining third raw data based on a first parameter, the first raw data, and the second raw data; and generating a third tomography image based on the third raw data, wherein the determining of the third raw data may be based on information about a distribution of the acquired photons, the information being included in at least one from among the first raw data and the second raw data.

    摘要翻译: 用于生成计算机断层摄影(CT)图像的断层摄影方法,包括:基于与接收到的包括获取的光子的X射线对应的第一原始数据生成第一断层摄影图像; 通过生成与第一断层图像相比具有增加的分辨率的第二断层图像并且对第二断层图像执行前向投影来确定第二原始数据; 基于第一参数,第一原始数据和第二原始数据确定第三原始数据; 以及基于所述第三原始数据生成第三断层图像,其中所述第三原始数据的确定可以基于关于所述获取的光子的分布的信息,所述信息被包括在所述第一原始数据和所述第二原始数据中的至少一个中, 第二个原始数据。

    APPARATUS AND METHOD FOR DATA RECOVERY OF RAW CT PROJECTION DATA AND CT IMAGING SYSTEM
    4.
    发明申请
    APPARATUS AND METHOD FOR DATA RECOVERY OF RAW CT PROJECTION DATA AND CT IMAGING SYSTEM 审中-公开
    用于原始CT投影数据和CT成像系统的数据恢复的装置和方法

    公开(公告)号:WO2017111998A1

    公开(公告)日:2017-06-29

    申请号:PCT/US2016/038476

    申请日:2016-06-21

    IPC分类号: A61B6/02 G01T1/29 G06T11/00

    摘要: The present invention provides a method for data recovery of raw CT projection data, comprising: determining a region to be estimated and a trusted region adjacent to the region to be estimated in raw CT projection data; and performing at least one of a first processing and a second processing. The first processing comprises: performing data fitting for CT projection data of the trusted region to obtain a space curved surface equation; re-estimating CT projection data of the region to be estimated according to the space curved surface equation. Said second processing comprises: acquiring multiple texture orientation information distributed in the trusted region according to the CT projection data of the trusted region; determining one or more matching lines in the region to be estimated according to each of the texture orientation information, each matching line passing through at least one data point to be estimated and being matched with at least one texture orientation information; performing interpolation operation along the matching lines, to re-estimate the CT projection data of the region to be estimated.

    摘要翻译: 本发明提供了一种用于原始CT投影数据的数据恢复的方法,包括:确定待估计区域以及与原始CT投影数据中待估计区域相邻的可信区域; 以及执行第一处理和第二处理中的至少一个。 第一种处理包括:对可信区域的CT投影数据进行数据拟合,得到空间曲面方程; 根据空间曲面方程重新估计待估计区域的CT投影数据。 所述第二处理包括:根据可信区域的CT投影数据,获取分布在可信区域中的多个纹理方向信息; 根据每一个纹理方向信息确定待估计区域中的一条或多条匹配线,每条匹配线通过待估计的至少一个数据点并与至少一个纹理方位信息匹配; 沿着匹配线执行插值操作,以重新估计待估计区域的CT投影数据。

    RADIATION DOSE REDUCTION AND IMPROVED CONSISTENCY BETWEEN SESSIONS IN HYBRID IMAGING STUDIES
    6.
    发明申请
    RADIATION DOSE REDUCTION AND IMPROVED CONSISTENCY BETWEEN SESSIONS IN HYBRID IMAGING STUDIES 审中-公开
    辐射剂量减少和混合成像研究中的会话之间的一致性改善

    公开(公告)号:WO2017072326A1

    公开(公告)日:2017-05-04

    申请号:PCT/EP2016/076139

    申请日:2016-10-28

    IPC分类号: A61B6/03 A61B6/00 G06F19/00

    摘要: In a multi-session imaging study, information from a previous imaging session is stored in a Binary Large Object (BLOB). Current emission imaging data are reconstructed into a non-attenuation corrected (NAC) current emission image. A spatial transform is generated aligning a previous NAC emission image from the BLOB to the current NAC emission image. A previous computed tomography (CT) image from the BLOB is warped using the spatial transform, and the current emission imaging data are reconstructed with attenuation correction using the warped CT image. Alternatively, low dose current emission imaging data and a current CT image are acquired, a spatial transform is generated aligning the previous CT image to the current CT image, a previous attenuation corrected (AC) emission image from the BLOB is warped using the spatial transform, and the current emission imaging data are reconstructed using the current CT image with the warped AC emission image as prior.

    摘要翻译: 在多会议成像研究中,来自先前成像会话的信息存储在二进制大对象(BLOB)中。 当前发射成像数据被重建为非衰减校正(NAC)电流发射图像。 生成空间变换,将来自BLOB的先前NAC发射图像与当前NAC发射图像对齐。 使用空间变换对来自BLOB的先前计算机断层摄影(CT)图像进行扭曲,并且使用扭曲的CT图像利用衰减校正来重建当前发射成像数据。 或者,获取低剂量电流发射成像数据和当前CT图像,生成将先前CT图像与当前CT图像对齐的空间变换,使用空间变换使来自BLOB的先前衰减校正(AC)发射图像变形 并且使用具有翘曲的AC发射图像的当前CT图像重建当前发射成像数据。

    SYSTEMS AND METHODS FOR X-RAY TOMOGRAPHY HAVING RETROGRADE FOCAL POSITIONING
    7.
    发明申请
    SYSTEMS AND METHODS FOR X-RAY TOMOGRAPHY HAVING RETROGRADE FOCAL POSITIONING 审中-公开
    用于具有逆向重点定位的X射线层析摄影的系统和方法

    公开(公告)号:WO2017066589A1

    公开(公告)日:2017-04-20

    申请号:PCT/US2016/057070

    申请日:2016-10-14

    摘要: A tomography apparatus includes a multi-focal point x-ray source, a support to travel a trajectory path, a detector having a plurality of pixels, where one of the multi-focal point x-ray source, the detector, and an item-under-test move on the support. A control processor controls a change in the focal point of the x-ray source at discrete points, or continuously, within a measurement region, the focal point change in a direction retrograde to the support arm travel, a detector memory accumulates a digital value representative of a signal charge from at least a portion of the plurality of pixels, the control processor reconstructs a volumetric image of the item-under-test by processing the detector memory contents. A method for continuous tomosynthesis and a computer-readable medium are also disclosed.

    摘要翻译: 一种层析成像设备包括多焦点X射线源,用于行进轨迹路径的支撑件,具有多个像素的检测器,其中多焦点X射线源中的一个 ,探测器和被测物品在支架上移动。 控制处理器控制X射线源的焦点在离散点处或连续地在测量区域内的变化,焦点在逆向于支撑臂行进的方向上变化,检测器存储器将数字值代表 来自所述多个像素的至少一部分的信号电荷,所述控制处理器通过处理所述检测器存储器内容来重建所述待测物体的体积图像。 还公开了一种用于连续断层合成的方法和一种计算机可读介质。

    DETECTOR ARM SYSTEMS AND ASSEMBLIES
    8.
    发明申请
    DETECTOR ARM SYSTEMS AND ASSEMBLIES 审中-公开
    检测器ARM系统和组件

    公开(公告)号:WO2017039787A1

    公开(公告)日:2017-03-09

    申请号:PCT/US2016/038352

    申请日:2016-06-20

    IPC分类号: A61B6/03 A61B6/00 G01T1/166

    摘要: A detector arm assembly is provided that includes a stator, a detector head, a radial motion motor, and a detector head belt. The stator is configured to be fixedly coupled to a gantry having a bore. The detector head includes a carrier section that is slidably coupled to the stator and configured to be movable in a radial direction in the bore relative to the stator. The radial motion motor is operably coupled to at least one of the detector head or the stator. The detector head belt is operably coupled to the radial motion motor and the carrier section. Rotation of the radial motion motor causes movement of the detector head in the radial direction.

    摘要翻译: 提供了一种检测器臂组件,其包括定子,检测器头,径向运动马达和检测器头带。 定子被构造成固定地连接到具有孔的机架。 检测器头包括载体部分,其可滑动地联接到定子并且构造成相对于定子在孔中沿径向可移动。 径向运动马达可操作地耦合到检测器头或定子中的至少一个。 检测器头带可操作地联接到径向运动马达和载体部分。 径向运动马达的旋转导致检测器头在径向上的移动。

    CFD SIMULATION ASSISTED 4D DSA RECONSTRUCTION
    9.
    发明申请
    CFD SIMULATION ASSISTED 4D DSA RECONSTRUCTION 审中-公开
    CFD模拟辅助4D DSA重建

    公开(公告)号:WO2017039646A1

    公开(公告)日:2017-03-09

    申请号:PCT/US2015/048050

    申请日:2015-09-02

    IPC分类号: G06T5/50 A61B6/00

    摘要: A computer-implemented method of reducing 4D Digital Subtracted Angiography (DSA) reconstruction artifacts using a computational fluid dynamics (CFD) simulation includes a computer receiving first DSA time sequence data comprising a representation of a plurality of vessels and segmenting a vessel of interest from the first DSA time sequence data. The computer uses the CFD simulation to simulate fluid dynamics across the vessel of interest to yield a flow field and determines a plurality of simulated time activity curve parameters for each voxel inside the vessel of interest using the flow field. Then, the computer applies a reconstruction process to second DSA time sequence data to yield a DSA volume. This reconstruction process is constrained by the plurality of simulated time activity curve parameters for each voxel inside the vessel of interest.

    摘要翻译: 使用计算流体动力学(CFD)模拟减少4D数字减影血管造影(DSA)重建伪影的计算机实现的方法包括计算机接收第一DSA时间序列数据,其包括多个血管的表示,并从 第一个DSA时间序列数据。 计算机使用CFD模拟来模拟感兴趣的血管的流体动力学,以产生流场,并使用流场确定感兴趣血管内的每个体素的多个模拟时间活动曲线参数。 然后,计算机将重建过程应用于第二DSA时间序列数据以产生DSA量。 该重建过程受到感兴趣的血管内的每个体素的多个模拟时间活动曲线参数的约束。