公开(公告)号：WO2017002126A1

公开(公告)日：2017-01-05

申请号：PCT/IL2016/050711

申请日：2016-07-03

Applicant: ASPECT AI LTD.

Inventor： RAPOPORT, Uri ,  SHAPIRA, Boaz

IPC: G01N24/08 ,  G01R33/563 ,  G01N11/02

CPC classification number: G01N24/081 ,  G01N24/085 ,  G01R33/4835 ,  G01R33/563

Abstract: System and method for analyzing changes in a fluid flowing through a conduit, including defining at least one coordinate within said conduit, said conduit having a first plurality of slices, receiving at least one known value for at least one property of the fluid, measuring said fluid using magnetic resonance, determining at least one image from the measured fluid, the at least one image having a second plurality of slices for said at least one coordinate, determining a second set of values for said at least one property of said fluid, comparing the first set of values and second set of values for said at least one property to determine a difference value, checking deviation of the determined difference from a predetermined value for said fluid, and issuing an alert if the deviation is not substantially zero.

Abstract translation: 用于分析流过导管的流体的变化的系统和方法，包括限定所述导管内的至少一个坐标，所述导管具有第一多个切片，接收至少一个已知值用于流体的至少一个性质，测量所述 使用磁共振的流体，从所测量的流体确定至少一个图像，所述至少一个图像具有用于所述至少一个坐标的第二多个切片，确定所述流体的所述至少一个性质的第二组值，比较 所述至少一个属性的第一组值和第二组值用于确定差值，检查所确定的差异与所述流体的预定值的偏差，以及如果偏差基本上不为零则发出警报。

公开(公告)号：WO2016189536A1

公开(公告)日：2016-12-01

申请号：PCT/IL2016/050549

申请日：2016-05-26

Applicant: ASPECT AI LTD.

Inventor： COHEN, Tal ,  RAPOPORT, Uri

IPC: G01N24/08 ,  G01N33/02

CPC classification number: G01N24/085 ,  G01N33/03

Abstract: Some embodiments are related to a portable or stationary system for determining the quality of processed food product. The system can be hand handled by a user, located on a production line or placed a laboratory. The system can include a Nuclear Magnetic Resonance (NMR) spectrometer and a controller. The controller can be configured to: receive an NMR spectrum of the processed food product from the NMR spectrometer, identify a first peak related to a first component of the processed food product from the received NMR spectrum and determine the quality of the processed food product based on the identification. The controller may further configured to control parameters of the production line based on the determined quality.

Abstract translation: 一些实施例涉及用于确定加工食品的质量的便携式或固定系统。 系统可以由位于生产线上的用户手工处理或放置在实验室。 该系统可以包括核磁共振（NMR）光谱仪和控制器。 控制器可以被配置为：从NMR光谱仪接收加工的食品的NMR光谱，从接收的NMR谱中鉴定与加工的食品的第一成分有关的第一个峰，并确定加工食品的质量 鉴定。 控制器还可以被配置为基于所确定的质量来控制生产线的参数。

公开(公告)号：WO2016083722A1

公开(公告)日：2016-06-02

申请号：PCT/FR2015/053183

申请日：2015-11-24

Applicant: TOTAL RAFFINAGE CHIMIE

Inventor： ADAM-BERRET, Matthieu ,  MARCHAL, Charles ,  LACROIX, Maxime ,  VENDRELL, Gloria

IPC: G01N24/08 ,  G01R33/44

CPC classification number: G01N24/082 ,  C10G45/00 ,  C10G45/16 ,  C10G2300/1059 ,  C10G2300/1096 ,  G01N24/085 ,  G01R33/285 ,  G01R33/421 ,  G01R33/448 ,  G06F17/156

Abstract: L'invention concerne une méthode de suivi d'un procédé de raffinage d'une charge d'hydrocarbures, dans laquelle: a)on acquiert par RMN du proton un signal représentatif du temps de relaxation transversale des différentes espèces d'un effluent issu dudit procédé de raffinage, notamment un effluent contenant des espèces solides, b)on modélise le signal mesuré à l'aide d'une fonction mathématique comportant plusieurs composantes, chaque composante correspondant à une gamme de dynamique des espèces dudit effluent, c)on extrait à partir de chacune des composantes de la fonction mathématique: -le temps de relaxation transversale de chacune des composantes, -l'intensité de chacune des composantes, d)on détermine une valeur de paramètre caractéristique dudit effluent à partir d'au moins une intensité déterminée à l'étape c), e)on génère un signal de commande du procédé de raffinage en fonction dudit paramètre caractéristique.

Abstract translation: 本发明涉及一种用于监测精炼烃原料的方法的方法，其包括：a）通过质子NMR获得表示来自所述精制方法的各种流出物的横向弛豫时间的信号，特别是流出物 b）使用包括若干组分的数学函数对所测量的信号进行建模，每个分量对应于所述流出物的种类的动态范围，c）从数学函数的每个分量中提取：横向弛豫 每个组件的时间 - 每个组件的强度，d）从步骤c）中确定的至少一个强度确定所述流出物的特征参数值，e）根据所述的步骤产生用于控制精炼过程的信号 特征参数。

公开(公告)号：WO2014027350A1

公开(公告)日：2014-02-20

申请号：PCT/IL2013/050690

申请日：2013-08-14

Applicant: ASPECT AI LTD.

Inventor： RAPOPORT, Uri

IPC: G01F1/56

CPC classification number: G01N11/04 ,  G01F1/716 ,  G01N24/085 ,  G01N2011/0006 ,  G01N2011/0086 ,  G01R33/5608 ,  G01R33/56308

Abstract: The present invention provides a method for determining rheological properties of a fluid, comprising steps of: a. providing an open-bore tube and defining within said bore a three dimensional grid (3DG) of voxels; b. defining at least two different cross sections, namely inlet cross section (ICS) and outlet cross section (OCS); c. defining a volume of interest (VOI) within said bore between said ICS and said OCS; d. obtaining rheological properties of said fluid; e. applying a pressure gradient to said bore between said ICS and said OCS; f. NMR imaging said fluid within said VOI; g. determining a velocity for said fluid v;; h. calculating shear rate values (SRV); i. calculating shear stress values (SSV) j. determining at least one rheological property RPi for each voxel Vox;; k. determining the difference in rheological property RPi for voxel Vox;; and 1. calculating 3D variations in said rheological property.

Abstract translation: 本发明提供了一种用于确定流体的流变性质的方法，包括以下步骤：a。 提供开孔管并且在所述孔内限定体素的三维网格（3DG）; 湾 限定至少两个不同的横截面，即入口横截面（ICS）和出口横截面（OCS）; C。 在所述ICS和所述OCS之间的所述孔内限定感兴趣体积（VOI）; 天。 获得所述流体的流变特性; 即 对所述ICS和所述OCS之间的所述孔施加压力梯度; F。 所述VOI内的NMR显示所述流体; G。 确定所述流体的速度; H。 计算剪切速率值（SRV）; 一世。 计算剪切应力值（SSV）j。 为每个体素Vox确定至少一个流变性质RPi; ķ。 确定体素Vox的流变性RPi的差异; 和1.计算所述流变性质的3D变化。

公开(公告)号：WO2013170944A1

公开(公告)日：2013-11-21

申请号：PCT/EP2013/001387

申请日：2013-05-10

Applicant: ISTITUTO DI RICERCHE CHIMICHE E BIOCHIMICHE "G. RONZONI" ,  ANGLO-ITALIAN CHEMOMETRICS LTD.

Inventor： TORRI, Giangiacomo ,  GUERRINI, Marco ,  RUDD, Timothy Robert

IPC: G01R33/46 ,  G01N24/08

CPC classification number: G01N24/00 ,  G01N24/085 ,  G01R33/4625

Abstract: A method of analysis of a heterogeneous product, for example heparin or heparin derivatives, to define whether said heterogeneous product is consistent with a library of verified heterogeneous samples (Library 1) by analysing the variation, natural or alien. The acceptable variation of the heterogeneous product is determined by comparing Library 1 with a second set of verified spectra (Library 2), by use of comparative two-dimensional correlation spectroscopic filtering (comparative 2D-COS-f). The method comprises obtaining a one-dimensional complex spectrum, for example 1 H- NMR spectra, of a heterogeneous product and testing if it has features that are greater than features found testing a spectrum from Library 2 against Library 1. In a second embodiment comparative 2D-COS-f with iterative random sampling (2D- COS-firs) is applied, which provides a more accurate and stable extraction of aliens/unnatural features. The method defines whether a test sample is consistent with a library of production norms of heterogeneous products; determines the acceptance criteria to be considered as normal production for heterogeneous products and detects species alien to the production norms of heterogeneous products.

Abstract translation: 分析异质产物（例如肝素或肝素衍生物）的方法，通过分析天然或外来变异来定义所述异质产物是否与已验证的异质样品库（Library 1）一致。 通过使用比较二维相关光谱滤波（比较2D-COS-f），通过比较文库1与第二组验证光谱（文库2）来确定异质产物的可接受变化。 该方法包括获得异构产物的一维复谱，例如1 H-NMR光谱，并测试其是否具有大于已发现从库2到库1测试光谱的特征的特征。在第二实施方案中，比较2D 使用-COS-f与迭代随机抽样（2D-COS-firs），提供了更准确和稳定的外星人/非自然特征提取。 该方法定义测试样本是否与异构产品的生产规范库一致; 确定被认为是异质产品的正常生产的验收标准，并检测与异质产品的生产规范不相符的物种。

公开(公告)号：WO2010088351A1

公开(公告)日：2010-08-05

申请号：PCT/US2010/022357

申请日：2010-01-28

Applicant: THE PROCTER & GAMBLE COMPANY ,  CETTI, Jonathan, Robert ,  PUTMAN, Christopher, Dean ,  FARRIS, Richard, Duffy ,  WEI, Karl, Shiqing ,  ABSHER, Sarah, Noelle ,  MENON, Elton, Luis ,  DICKER, John, Andrew

Inventor： CETTI, Jonathan, Robert ,  PUTMAN, Christopher, Dean ,  FARRIS, Richard, Duffy ,  WEI, Karl, Shiqing ,  ABSHER, Sarah, Noelle ,  MENON, Elton, Luis ,  DICKER, John, Andrew

IPC: B65B3/32 ,  B65B43/59 ,  A61K8/03 ,  A61Q5/02 ,  B65D77/08

CPC classification number: G01R33/44 ,  A45D34/04 ,  A45D40/24 ,  A61K8/03 ,  A61K8/31 ,  A61K2800/88 ,  A61Q19/10 ,  B65B3/326 ,  B65B43/59 ,  G01N24/085

Abstract: A method of testing a packaged personal care composition is disclosed. The method includes the steps of dispensing a dose of a personal care composition from a package, wherein the personal care composition is made from a first composition having a surfactant and a second composition having a hydrophobic benefit material and wherein the concentrations of the surfactant and the hydrophobic benefit material vary by weight of the personal care composition from a first end of the package to a second end of the package. The doses of the personal care composition are centrifuged to separate the surfactant from the hydrophobic benefit material and the concentration of the hydrophobic material is determined. These steps are repeated until all of the personal care composition is dispensed form the package.

Abstract translation: 公开了一种测试包装的个人护理组合物的方法。 该方法包括从包装中分配剂量的个人护理组合物的步骤，其中个人护理组合物由具有表面活性剂的第一组合物和具有疏水有益材料的第二组合物制成，并且其中表面活性剂和 疏水益处材料随着包装的第一端到包装的第二端的个人护理组合物的重量而变化。 将个人护理组合物的剂量离心以将表面活性剂与疏水性有益物质分离，并测定疏水性物质的浓度。 重复这些步骤，直到所有的个人护理组合物从包装中分配出来。

公开(公告)号：WO2007144206A3

公开(公告)日：2008-04-24

申请号：PCT/EP2007005436

申请日：2007-06-14

Applicant: BOC GROUP PLC ,  BRUKER BIOSPIN GMBH ,  CORVER JOSEF ANTONIUS WILLEM M ,  SCHMALBEIN KLAUS-DIETER ,  MAIER DIETHER C ,  KAMLOWSKI ANDREAS ,  DAMEN FRANCISCUS ANTONIUS

Inventor： CORVER JOSEF ANTONIUS WILLEM M ,  SCHMALBEIN KLAUS-DIETER ,  MAIER DIETHER C ,  KAMLOWSKI ANDREAS ,  DAMEN FRANCISCUS ANTONIUS

IPC: G01R33/44

CPC classification number: G01N24/085

Abstract: A method is described for determining a characteristic, such as the mass, of each of a plurality of samples. The method comprises the steps of providing a plurality of coil elements each for surrounding a respective sample, causing the samples to enter an interrogation zone, each sample being surrounded by a respective coil element when it is located within the interrogation zone, applying a magnetic field in a first direction in the interrogation zone for creating in a pre-polarised state a net nuclear magnetisation of a nuclear spin species within a sample located in the interrogation zone, applying, by each coil element surrounding a respective sample located in the interrogation zone, an RF field in a second direction for temporarily changing the net nuclear magnetisation of the nuclear spin species in the sample, detecting RF energy emitted from that sample as the net nuclear magnetisation of the nuclear spin species in the sample relaxes, and, from the detected RF energy, determining the characteristic of each sample located in the interrogation zone.

Abstract translation: 描述了一种用于确定多个样本中的每一个的特征（例如质量）的方法。 该方法包括以下步骤：提供多个线圈元件，每个线圈元件用于围绕相应的样品，使得样品进入询问区域，每个样品在位于询问区域内时由相应的线圈元件围绕，施加磁场 在询问区中的第一方向上，用于在预极化状态下产生位于询问区内的样品内的核自旋物质的净核磁化，由围绕位于询问区中的相应样品的每个线圈元件施加， 用于临时改变样品中核自旋物质的净核磁化的第二方向的RF场，当样品中的核自旋物质的净核磁化松弛时，检测从该样品发射的RF能量，并且从检测到的 RF能量，确定位于询问区的每个样本的特征。

公开(公告)号：WO2006114588A3

公开(公告)日：2006-12-14

申请号：PCT/GB2006001471

申请日：2006-04-21

Applicant: BOC GROUP PLC ,  BONS VINCENT ALEXANDER ,  SCHAEPMAN ALEXANDER CLEMENS HE ,  KRIECKAART JOSEFHUS FRANCISCA ,  CORVER JOZEF ANTONIUS WILLEM M

Inventor： BONS VINCENT ALEXANDER ,  SCHAEPMAN ALEXANDER CLEMENS HE ,  KRIECKAART JOSEFHUS FRANCISCA ,  CORVER JOZEF ANTONIUS WILLEM M

IPC: G01R33/44

CPC classification number: G01N24/085

Abstract: A method of determining the mass of a moving sample is described, in which the sample is moved at a controlled velocity through a mass interrogation zone and a temperature interrogation zone, which may be upstream or downstream from the mass interrogation zone. Using a magnetic resonance method, a first signal is generated as the sample passes through the mass interrogation zone, the first signal having a characteristic that varies with the mass of the sample and with the temperature of the sample. A beam of electromagnetic radiation of a terahertz frequency or a near-infrared wavelength is generated and directed through the temperature interrogation zone. As the sample moves through the temperature interrogation zone, the electromagnetic radiation reflected from or transmitted through the sample is detected, and from that detected electromagnetic radiation a second signal is generated that has a characteristic that varies with the temperature of the sample. The characteristic of the first signal is adjusted using the second signal to produce a temperature compensated characteristic, which is compared to a similar characteristic obtained from a similar sample of known mass to determine the mass of the sample.

Abstract translation: 描述了确定移动样品的质量的方法，其中样品以受控的速度通过质量询问区和温度询问区移动，该质询讯问区和温度询问区可以在质询问区的上游或下游。 使用磁共振方法，当样品通过质量询问区时，产生第一信号，第一信号具有随样品质量和样品温度而变化的特性。 产生太赫兹频率或近红外波长的电磁辐射束并引导通过温度询问区。 当样品移动通过温度询问区时，检测从样品反射或透过样品的电磁辐射，并从该检测到的电磁辐射中产生具有随试样温度变化的特性的第二信号。 使用第二信号调整第一信号的特性以产生温度补偿特性，其与从已知质量的相似样品获得的类似特性进行比较，以确定样品的质量。

公开(公告)号：WO2005124324A1

公开(公告)日：2005-12-29

申请号：PCT/EP2005/052683

申请日：2005-06-09

Applicant: BASELL POLYOLEFINE GMBH ,  MIHAN, Shahram ,  LILGE, Dieter ,  ROHDE, Wolfgang

Inventor： MIHAN, Shahram ,  LILGE, Dieter ,  ROHDE, Wolfgang

IPC: G01N24/08

CPC classification number: G01N24/08 ,  C08F10/02 ,  C08F110/02 ,  C08F210/16 ,  C08F2400/02 ,  G01N24/085 ,  G01R33/44 ,  Y02P20/125 ,  C08F2/00

Abstract: Method of determining the composition of polymer mixtures comprising defined polymer components of differing mean molar masses M n , which comprises the steps (a) recording of at least one 1 H-NMR relaxation curve of the polymer mixture and (b) calculating the proportions of the polymer components by matching the measured relaxation curve with the relaxation curves of the individual polymer components. In this way, the composition of polymer mixtures can be determined quickly and simply. Furthermore, process integration for regulating the polymerization is possible.

Abstract translation: 确定包含不同平均摩尔质量Mn的限定的聚合物组分的聚合物混合物的组成的方法，其包括步骤（a）记录聚合物混合物的至少一个1 H-NMR松弛曲线，（b）计算比例 通过将测量的松弛曲线与各个聚合物组分的松弛曲线相匹配来获得聚合物组分。 以这种方式，可以快速且简单地确定聚合物混合物的组成。 此外，用于调节聚合的方法集成是可能的。

公开(公告)号：WO2005111660A1

公开(公告)日：2005-11-24

申请号：PCT/US2004/020890

申请日：2004-06-30

Applicant: THE BOC GROUP, INC. ,  APTAKER, Peter ,  SELWAY, Robert ,  HENDRICKX, Paulus C. J. M. ,  CORVER, Jozef A. W. M. ,  BONS, Vincent

Inventor： APTAKER, Peter ,  SELWAY, Robert ,  HENDRICKX, Paulus C. J. M. ,  CORVER, Jozef A. W. M. ,  BONS, Vincent

IPC: G01V3/00

CPC classification number: G01R33/34046 ,  G01N24/085

Abstract: A radio frequency (RF) probe for a nuclear magnetic resonance check weighing system produces uniform magnetic field at the center of RF probe , has minimal sensitivity to electrical interference from external sources, shapes the magnetic field to minimize cross coupling from packages such as drug vials not under test, and presents minimal airflow obstruction. RF probe includes a coil with a plurality of conductive loops having a rectangular cross section carried inside two opposing, rectangular cross section housings , respectively. Housings are spaced apart and in parallel, creating an "open probe" configuration permitting a conveyor belt carrying vials whose contents are to be checked to pass between housings, and allows airflow surrounding the vials and conveyor belt to pass substantially without obstruction. Conductive loops and the housings carrying them may be placed such that the longitudinal axis of coil is oriented in either horizontal or vertical spatial relation with conveyor belt.

Abstract translation: 用于核磁共振检测称重系统的射频（RF）探针在RF探头的中心产生均匀的磁场，对来自外部源的电气​​干扰具有最小的灵敏度，使磁场形成最小化，以使来自诸如药物小瓶的包装的交叉耦合最小化 没有被测试，并且呈现最小的气流阻塞。 射频探针包括一个线圈，该线圈具有分别承载在两个相对的矩形横截面壳体内的矩形横截面的多个导电环。 壳体间隔开并联，产生“开放式探头”构造，允许携带其内容物检查的小瓶的输送带带通过壳体之间，并且允许围绕小瓶和输送带的气流基本上无障碍地通过。 导电环和承载它们的壳体可以被放置成使得线圈的纵向轴线以与输送带的水平或垂直空间关系定向。