公开(公告)号：WO2017177197A1

公开(公告)日：2017-10-12

申请号：PCT/US2017/026706

申请日：2017-04-07

Applicant: THE JOHNS HOPKINS UNIVERSITY

Inventor： ZHANG, Yi ,  ZHOU, Jinyuan ,  BOTTOMLEY, Paul A.

IPC: A61B5/055 ,  G01R33/44 ,  G01R33/24

CPC classification number: G01R33/246 ,  G01R33/4806 ,  G01R33/50 ,  G01R33/5605 ,  G01R33/5611 ,  G01R33/56341 ,  G01R33/56366

Abstract: A method of spatially imaging a nuclear magnetic resonance (NMR) parameter whose measurement requires the acquisition of spatially localized NMR signals in a sample includes placing the sample in an MRI apparatus with a plurality of MRI detectors each having a spatial sensitivity map; and applying MRI sequences adjusted to be sensitive to the NMR parameter. At least one of the MRI sequences is adjusted so as to substantially fully sample an image k-space of the sample. The remainder of the MRI sequences is adjusted to under-sample the image k-space. The method further includes acquiring image k-space NMR signal data sets; estimating a sensitivity map of each of the MRI detectors using a strategy to suppress unfolding artefacts; and applying the estimated sensitivity maps to at least one of the image k-space NMR signal data sets to reconstruct a spatial image of NMR signals that are sensitive to the NMR parameter.

Abstract translation: 空间成像核磁共振（NMR）参数的方法，其测量需要获取样品中的空间定位的NMR信号，包括将样品置于具有多个MRI检测器的MRI设备中，每个MRI检测器具有 空间敏感度图; 并应用调整为对NMR参数敏感的MRI序列。 调整至少一个MRI序列以基本上完​​全采样样本的图像k-空间。 将其余的MRI序列调整为对图像k空间进行欠采样。 该方法还包括获取图像k空间NMR信号数据组; 使用抑制展开伪影的策略估计每个MRI检测器的敏感度图; 以及将估计的灵敏度图应用于图像k空间NMR信号数据集中的至少一个，以重构对NMR参数敏感的NMR信号的空间图像。

公开(公告)号：WO2016180640A1

公开(公告)日：2016-11-17

申请号：PCT/EP2016/059454

申请日：2016-04-28

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： NEHRKE, Kay ,  BOERNERT, Peter

IPC: G01R33/24 ,  G01R33/561

CPC classification number: G01R33/5611 ,  G01R33/243 ,  G01R33/246 ,  G01R33/5608 ,  G01R33/5612

Abstract: The invention relates to a method of MR imaging of an object (10). The problem of the invention is to provide an improved MR imaging technique that enables fast and robust determination of spatial sensitivity profiles of RF receiving antennas (11, 12, 13) used in parallel imaging as well as B1 and/or B0 mapping. The method of the invention comprises subjecting the object (10) to a stimulated echo sequence. Two or more stimulated echo signals (STE, STE*) are acquired, namely a direct stimulated echo signal (STE) and a conjugated stimulated echo signal (STE*), wherein at least one of the stimulated echo signals (STE, STE*) is received in parallel via an array of two or more RF receiving antennas (11, 12, 13) having different spatial sensitivity profiles, and wherein at least another one of the stimulated echo signals (STE, STE*)is received via a body RF coil (9) having an essentially homogeneous spatial sensitivity profile. Sensitivity maps indicating the spatial sensitivity profiles of the individual RF receiving antennas (11, 12, 13) of the array are derived by comparing the stimulated echo signals (STE, STE*) received via the array of RF receiving antennas (11, 12, 13) with the stimulated echo signals (STE, STE*) received via the body RF coil (9). Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).

Abstract translation: 本发明涉及一种物体（10）的MR成像方法。 本发明的问题是提供一种改进的MR成像技术，其能够快速和鲁棒地确定在并行成像以及B1和/或B0映射中使用的RF接收天线（11,12,13）的空间灵敏度分布。 本发明的方法包括使物体（10）经受刺激的回波序列。 获得两个或多个受激回波信号（STE，STE *），即直接受激回波信号（STE）和共轭刺激回波信号（STE *），其中至少一个受激回波信号（STE，STE *） 经由具有不同空间灵敏度分布的两个或更多个RF接收天线（11,12,13）的阵列并行接收，并且其中至少另一个被刺激的回波信号（STE，STE *）经由身体RF 线圈（9）具有基本均匀的空间灵敏度分布。 通过比较经由RF接收天线阵列（11,12,13）接收的受激回波信号（STE，STE *），得到表示阵列的各个RF接收天线（11,12,13）的空间灵敏度分布的灵敏度图， 13）通过身体RF线圈（9）接收的受激回波信号（STE，STE *）。 此外，本发明涉及MR装置（1）和用于MR装置（1）的计算机程序。

公开(公告)号：WO2016109234A1

公开(公告)日：2016-07-07

申请号：PCT/US2015/066407

申请日：2015-12-17

Applicant: GENERAL ELECTRIC COMPANY

Inventor： GUI, Dawei ,  ZHAO, Xiaoli ,  ZHANG, Zhenghui ,  SHEN, Hao ,  GARNIER, Stephen

IPC: G01R33/20 ,  G01R33/32 ,  G01R33/38

CPC classification number: G01R33/5659 ,  G01R33/246

Abstract: A controller that is operatively connected with a magnet assembly, which defines a target volume; and an image processor, which is configured to obtain calibration data from the controller; map B1 transmit intensity from the magnet assembly to the target volume, based on the calibration data; calculate a B1 transmit shading correction based at least on the map of B1 transmit intensity and on pulse sequence parameters; obtain k-space data of an imaging subject within the target volume from the controller operating the magnet assembly based on the pulse sequence parameters; develop an MR image from the k-space data; and apply the B1 transmit shading correction to the MR image.

Abstract translation: 控制器，其与限定目标体积的磁体组件可操作地连接; 以及图像处理器，被配置为从所述控制器获取校准数据; 基于校准数据将B1发射强度从磁体组件到目标体积; 至少基于B1发送强度和脉冲序列参数的映射计算B1发送阴影校正; 基于所述脉冲序列参数从所述控制器操作所述磁体组件获得所述目标体积内的成像对象的k空间数据; 从k空间数据开发MR图像; 并将B1发送阴影校正应用于MR图像。

公开(公告)号：WO2011039692A2

公开(公告)日：2011-04-07

申请号：PCT/IB2010/054339

申请日：2010-09-27

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH ,  FUDERER, Miha ,  ROZIJN, Thomas, Hendrik ,  KATSCHER, Ulrich ,  NEHRKE, Kay ,  HARVEY, Paul, Royston

Inventor： FUDERER, Miha ,  ROZIJN, Thomas, Hendrik ,  KATSCHER, Ulrich ,  NEHRKE, Kay ,  HARVEY, Paul, Royston

CPC classification number: G01R33/5612 ,  G01R33/246 ,  G01R33/5659

Abstract: The invention relates to a magnetic resonance imaging apparatus comprising an array of two or more RF antennas(9) for transmitting RF pulses to and receiving MR signals from a body(7) of a patient positioned in an examination volume (2), the RF antennas (9) having spatial transmit and receive sensitivity profiles. The apparatus is arranged to: -control the temporal succession, the phase, and the amplitude of the RF feeding of each individual RF antenna (9), the phases and amplitudes being determined from the spatial transmit sensitivity profiles of the RF antennas(9), and -reconstruct a MR image from a combination of the received MR signals received via the individual RF antennas(9) and from the spatial receive sensitivity profiles of the RF antennas(9). The invention proposes that the apparatus is further arranged to: -determine the spatial transmit sensitivity profiles of the RF antennas (9) from the spatial receive sensitivity profiles of the RF antennas (9), or -determine the spatial receive sensitivity profiles of the RF antennas (9) from the spatial transmit sensitivity profiles of the RF antennas (9).

Abstract translation: 磁共振成像装置技术领域本发明涉及一种磁共振成像设备，其包括用于将RF脉冲发射到患者身体（7）并从患者身体（7）接收MR信号的两个或更多个RF天线（9）的阵列， 检查体积（2），所述RF天线（9）具有空间发射和接收灵敏度分布。 该设备被布置为： - 控制每个单独的RF天线（9）的RF馈送的时间顺序，相位和幅度，相位和幅度根据RF天线（9）的空间发射灵敏度曲线确定， 并且 - 从经由各个RF天线（9）接收到的MR信号的组合以及从RF天线（9）的空间接收灵敏度简档中重建MR图像。 本发明提出，该设备还被布置为： - 根据RF天线（9）的空间接收灵敏度分布来确定RF天线（9）的空间发射灵敏度分布，或者 - 确定RF 天线（9）与RF天线（9）的空间发射灵敏度分布相匹配。

公开(公告)号：WO2010032172A1

公开(公告)日：2010-03-25

申请号：PCT/IB2009/053956

申请日：2009-09-10

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH ,  BOERNERT, Peter ,  KOKEN, Peter ,  NEHRKE, Kay ,  KATSCHER, Ulrich ,  GRAESSLIN, Ingmar

Inventor： BOERNERT, Peter ,  KOKEN, Peter ,  NEHRKE, Kay ,  KATSCHER, Ulrich ,  GRAESSLIN, Ingmar

IPC: G01R33/3415 ,  G01R33/58

CPC classification number: G01R33/583 ,  G01R33/246 ,  G01R33/3415 ,  G01R33/4838 ,  G01R33/5612 ,  G01R33/5659 ,  G01R33/586

Abstract: The invention relates to a method of acquiring MRI image data comprising the following steps: performing a 3 -dimensional Bl mapping of a first volume using a first voxel size, selecting an MRI protocol, performing the Bl -shim in accordance with the MRI protocol, performing the MRI protocol to acquire MRI imaging data of a second volume using a second voxel size, wherein the first voxel size is larger than the second voxel size, wherein the first volume is larger than the second volume, and wherein the second volume is contained within the first volume.

Abstract translation: 本发明涉及一种获取MRI图像数据的方法，包括以下步骤：使用第一体素大小执行第一体积的3维B1映射，选择MRI协议，根据MRI协议执行Bl-shim， 执行MRI协议以使用第二体素尺寸获取第二体积的MRI成像数据，其中所述第一体素大小大于所述第二体素大小，其中所述第一体积大于所述第二体积，并且其中所述第二体积被包含 在第一卷内。

公开(公告)号：WO2009118702A2

公开(公告)日：2009-10-01

申请号：PCT/IB2009051258

申请日：2009-03-26

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  NEHRKE KAY ,  BOERNERT PETER ,  VOIGT TOBIAS RATKO ,  KATSCHER ULRICH

Inventor： NEHRKE KAY ,  BOERNERT PETER ,  VOIGT TOBIAS RATKO ,  KATSCHER ULRICH

IPC: G01R33/3415 ,  G01R33/565

CPC classification number: G01R33/586 ,  G01R33/246 ,  G01R33/3415 ,  G01R33/5612 ,  G01R33/56518 ,  G01R33/5659

Abstract: A magnetic resonance method includes performing a plurality of magnetic resonance excitation operations each using a different sub-set of a set of radio frequency transmit coils (30), each sub-set including more than one radio frequency transmit coil, acquiring magnetic resonance data responsive to each said magnetic resonance excitation operation, and computing a B1 or flip angle map for each radio frequency transmit coil of the set of radio frequency transmit coils based on the acquired magnetic resonance data. A magnetic resonance method includes performing an actual flip angle mapping (AFI) sequence using a radio frequency transmit coil (32) with a ratio TR1 : TR2 of the TR times of the AFI sequence selected to be rational, acquiring magnetic resonance data responsive to said AFI sequence, and computing a B1 or flip angle map for the radio frequency transmit coil based on the acquired magnetic resonance data.

Abstract translation: 磁共振方法包括使用一组射频发射线圈（30）的不同子集执行多个磁共振激励操作，每个子集包括多于一个射频发射线圈，响应于磁共振数据 到每个所述磁共振激励操作，以及基于所获取的磁共振数据计算所述射频发射线圈组中的每个射频发射线圈的B1或翻角图。 磁共振方法包括使用射频发射线圈（32）执行实际的翻转角映射（AFI）序列，其中AFI序列的TR次的比值TR1：TR2被选择为合理，获取响应于所述的 AFI序列，并且基于获取的磁共振数据计算用于射频发射线圈的B1或翻转角图。

公开(公告)号：WO2007098011A2

公开(公告)日：2007-08-30

申请号：PCT/US2007004040

申请日：2007-02-17

Applicant: UNIV MINNESOTA ,  VAUGHAN J THOMAS ,  VAN DE MOORTELE PIERRE-FRANCOI ,  DELABARRE LANCE ,  OLSON CHRIS ,  ORSER HEATHER ,  GOPINATH ANAND ,  UGURBIL KAMIL ,  SNYDER CARL ,  ADRIANY GREGOR ,  AKGUN CAN E ,  TIAN JINFENG ,  STRUPP JOHN ,  ANDERSON PETER M ,  WU XIAOPING

Inventor： VAUGHAN J THOMAS ,  VAN DE MOORTELE PIERRE-FRANCOI ,  DELABARRE LANCE ,  OLSON CHRIS ,  ORSER HEATHER ,  GOPINATH ANAND ,  UGURBIL KAMIL ,  SNYDER CARL ,  ADRIANY GREGOR ,  AKGUN CAN E ,  TIAN JINFENG ,  STRUPP JOHN ,  ANDERSON PETER M ,  WU XIAOPING

IPC: G01R33/46

CPC classification number: G01R33/583 ,  G01R33/246 ,  G01R33/341 ,  G01R33/5612

Abstract: This document discloses, among other things, multi-channel magnetic resonance using a TEM coil.

Abstract translation: 本文件尤其公开了使用TEM线圈的多通道磁共振。

公开(公告)号：WO2006114749A1

公开(公告)日：2006-11-02

申请号：PCT/IB2006/051251

申请日：2006-04-21

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH ,  GRAESSLIN, Ingmar ,  VERNICKEL, Peter ,  SCHMIDT, Joachim ,  FINDEKLEE, Christian

Inventor： GRAESSLIN, Ingmar ,  VERNICKEL, Peter ,  SCHMIDT, Joachim ,  FINDEKLEE, Christian

IPC: G01R33/3415 ,  G01R33/58

CPC classification number: G01R33/5612 ,  G01R33/246 ,  G01R33/3415 ,  G01R33/58 ,  G01R33/583

Abstract: Methods and circuit arrangements for operating multi-channel transmit / receive antenna devices or arrangements especially for use in magnetic resonance imaging (MRI) systems are disclosed, by which a fully independent control of complete multi-channel RF transmit and receive chains can be conducted in a flexible way and new options like RF shimming, transmit sensitivity encoding (TransmitSENSE), RF encoding, determination of S- or Z-matrix prior to spin echo measurements, calibration, SAR (specific absorption rate) reduction etc. can be utilized or improved.

Abstract translation: 公开了用于操作多通道发射/接收天线装置或特别用于磁共振成像（MRI）系统的装置的方法和电路装置，通过该装置可以完全独立地控制完整的多通道RF发射和接收链， 可以利用或改进灵活的方式和新的选项，如RF匀场，发射灵敏度编码（TransmitSENSE），RF编码，自旋回波测量之前的S或Z矩阵的确定，校准，SAR（比吸收率）降低等） 。

公开(公告)号：WO2005022184A1

公开(公告)日：2005-03-10

申请号：PCT/IB2004/051422

申请日：2004-08-09

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  FUDERER, Miha ,  KLEIHORST, Robert

Inventor： FUDERER, Miha ,  KLEIHORST, Robert

IPC: G01R33/32

CPC classification number: G01R33/246 ,  G01R33/3415 ,  G01R33/5611 ,  G01R33/5659

Abstract: The invention relates to a method for determination of spatial sensitivity profiles of RF transmit and/or receive coils (7, 8, 9) in an examination volume (17) of a magnetic resonance (MR) imaging device (1). In accordance with the method of the invention, nuclear magnetization is excited within the examination volume (17) by a sequence of RF pulses and switched magnetic field gradients, wherein the sequence comprises RF pulses with at least two different excitation flip angles. MR signals are acquired and processed so as to form at least two MR images, each corresponding to one of these flip angles. The spatial sensitivity profiles are then computed in the positions of the pixels or voxels of the MR images based upon the dependence of the pixel or voxel values on the respective flip angles. Alternatively, a plurality of instances of a sequence of RF pulses and switched magnetic field gradients is applied and MR signals are acquired, wherein a different combination of transmit and receive coils (7, 8, 9) is used for each instance of the sequence. The spatial sensitivity profiles are then computed in the positions of the pixels or voxels of the MR images formed from the acquired MR signals by taking the logarithm of the pixel or voxel values and by solving a linear system of equations for each pixel or voxel.

Abstract translation: 本发明涉及一种用于确定在磁共振（MR）成像装置（1）的检查体积（17）中的RF发射和/或接收线圈（7,8,9）的空间灵敏度分布的方法。 根据本发明的方法，通过一系列RF脉冲和切换的磁场梯度，在检查体积（17）内激发核磁化，其中该序列包括具有至少两个不同激发翻转角的RF脉冲。 获取和处理MR信号以形成至少两个MR图像，每个MR图像对应于这些翻转角之一。 然后基于像素或体素值对相应翻转角的依赖性，在MR图像的像素或体素的位置中计算空间灵敏度分布。 或者，施加RF脉冲序列和开关磁场梯度的多个实例，并且获取MR信号，其中发射和接收线圈（7,8,9）的不同组合用于序列的每个实例。 然后，通过采取像素或体素值的对数，并通过求解每个像素或体素的线性方程组，在由所获取的MR信号形成的MR图像的像素或体素的位置中计算空间灵敏度分布。

公开(公告)号：WO1997042517A1

公开(公告)日：1997-11-13

申请号：PCT/IL1997000146

申请日：1997-05-05

Applicant: BIOSENSE INC. ,  OSADCHY, Daniel ,  GOVARI, Assaf

Inventor： BIOSENSE INC.

IPC: G01R35/00

CPC classification number: G01R33/246 ,  A61B5/06 ,  A61B5/062 ,  G01R33/02 ,  G01R33/58 ,  G01R35/00

Abstract: A method for calibrating a magnetic field generator (40) including fixing one or more magnetic field sensors (20, 22, 24) to a probe (26) in known positions and orientations and selecting one or more known locations in the vicinity of the magnetic field generator. The magnetic field generator (40) is driven so as to generate a magnetic field. The probe (26) is moved in a predetermined, known orientation to each of the one or more locations, and signals are received from the one or more sensors at each of the one or more locations. The signals are processed to measure the amplitude and direction of the magnetic field, at the respective positions of the one or more sensors and to determine calibration factors relating to the amplitude and direction of the magnetic field in the vicinity of the magnetic field generator.

Abstract translation: 一种用于校准磁场发生器（40）的方法，包括将已知位置和取向中的一个或多个磁场传感器（20,22,24）固定到探针（26），并选择磁性附近的一个或多个已知位置 场发生器。 磁场发生器（40）被驱动以产生磁场。 探针（26）以预定的已知方向移动到一个或多个位置中的每个位置，并且在一个或多个位置中的每一个处从一个或多个传感器接收信号。 处理这些信号以测量一个或多个传感器的相应位置处的磁场的振幅和方向，并且确定与磁场发生器附近的磁场的振幅和方向有关的校准因子。