公开(公告)号：WO2022101361A2

公开(公告)日：2022-05-19

申请号：PCT/EP2021/081422

申请日：2021-11-11

Applicant: ASTRAZENECA AB ,  UNIVERSITY OF LEEDS

Inventor： WANG, Yinhai ,  FREEMAN, Adrian Mark

IPC: A61K31/4545 ,  A61K31/573 ,  A61L15/44 ,  A61P3/10 ,  A61P17/02 ,  G16H15/00 ,  G16H30/40 ,  G16H50/20 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/445 ,  A61B5/7267 ,  A61K45/06 ,  A61K9/0053 ,  A61L2300/432 ,  A61L26/0066

Abstract: A method of assessing a wound in a subject is provided. The method comprises obtaining one or more optical coherence tomography images of the wound and analysing the one or more optical coherence tomography images using a deep learning model that has been trained to classify pixels in an optical coherence tomography image of a wound between a plurality of classes comprising a plurality of classes associated with different types of wound tissue, thereby obtaining for each image analysed, an indication of the location of tissue likely to belong to each of the different types of wound tissue in the respective image.

公开(公告)号：WO2022003360A1

公开(公告)日：2022-01-06

申请号：PCT/GB2021/051676

申请日：2021-07-01

Applicant: COMIND TECHNOLOGIES LIMITED

Inventor： DACOMBE, James Robert

IPC: A61B5/00 ,  A61B6/03 ,  A61B6/00 ,  A61B8/00 ,  G01S15/89 ,  G01N21/17 ,  G01N21/49 ,  A61B5/0073 ,  A61B5/0097 ,  A61B8/0808 ,  A61B8/4209

Abstract: The disclosure provides brain tissue acousto-optic apparatus and methods. The apparatus comprises an optical source (201) configured to emit light towards a target volume (250) containing brain tissue of a living subject, an optical detector (202) configured to detect light from the target volume, and an ultrasound source (203) arranged to provide an ultrasound field of spatially varying ultrasound amplitude in the target volume. The ultrasound field is arranged to modify the optical path length of light (212, 214) passing through the target volume (250), and to define a plurality of regions (210a-210f) in the target volume (250), wherein each region (210a-210f) provides a unique modification of the optical path length (212, 214).

公开(公告)号：WO2022169592A2

公开(公告)日：2022-08-11

申请号：PCT/US2022/012908

申请日：2022-01-19

Applicant: VIVONICS, INC.

Inventor： MYERS, Ryan ,  DIMATTEO, Kristian ,  DUPNIK, Michaelina

IPC: A61B5/087 ,  A61B5/0205 ,  A61B5/024 ,  A61B5/083 ,  A61B5/1455 ,  A61B5/1477 ,  A61B5/0073 ,  A61B5/0075 ,  A61B5/02405 ,  A61B5/0816 ,  A61B5/14542 ,  A61B5/6833 ,  A61B5/72

Abstract: A system for detecting and/or monitoring at least one of pneumothorax,hemopneumolhorax, or hemothorax using one or more light sources and one or more lightdetectors. The system includes one or more light sources adapted to be placed on skirt of aliving subject The one or more tight detectors are adapted to be placed on the skin of theliving subject. A processing subsystem is coupled to the one or1 more light sources and theone or rnore tight detectors detects and/or monitors the presence of at least one ofpneumothorax, hen»pneumothorax, or hemothorax in the living subject.

公开(公告)号：WO2021203029A1

公开(公告)日：2021-10-07

申请号：PCT/US2021/025624

申请日：2021-04-02

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： SGUIGNA, Peter V. ,  GREENBURG, Benjamin M. ,  CONGER, Darrel

IPC: A61B3/102 ,  A61B3/1233 ,  A61B3/1241 ,  A61B3/14 ,  A61B3/0008 ,  A61B5/0073 ,  A61B5/489 ,  A61B5/2007 ,  A61B5/1075 ,  A61B5/1079

Abstract: Systems and methods for performing a retinal angiogram, which can be used to non-invasively quantify retinal perfusion by measuring differences in retinal vascular density. The systems and methods can be used to measure a response of the vasculature, particularly in the choriocapillaris. The systems and methods can be used to diagnose neurodegenerative conditions, associated sleep and mood disorders, and measure metabolic reserve. In particular, the systems and methods can also be used for both diagnostics and prognostics.