AN EGGSHELL AND EGSHELL MEMBRANE CONTAINING DENTAL VARNISH

    公开(公告)号:WO2022216256A2

    公开(公告)日:2022-10-13

    申请号:PCT/TR2022/050250

    申请日:2022-03-21

    IPC分类号: A61K6/20 A61K35/57 A61K6/74

    摘要: The invention is related to a florine-free dental varnish, which is applied on the tooth surface to prevent development and progress of dental caries in demineralised enamel, on the other hand contributing alleviaton of gingival inflammations and regeneration of gingival lesions, not stimulating gag and split reflex with its aroma, hardening soon after appliying to the tooth surface, not causing allergic reactions and systemic or local toxications, not containing florine, containing micronized eggshell powder and tri-sodium tri-metaphosphate adsorbed eggshell membrane.

    基于微环境诱导纳米粒子再沉积的牙本质粘接预处理组合物及用途

    公开(公告)号:WO2022088520A1

    公开(公告)日:2022-05-05

    申请号:PCT/CN2021/072218

    申请日:2021-01-15

    申请人: 浙江大学

    摘要: 一种基于微环境诱导纳米粒子再沉积的牙本质粘接预处理组合物,包含二元体系或者三元体系,该组合物应用在牙本质酸蚀处理之后、粘接剂使用之前。该粘接预处理剂可以在酸蚀后脱矿牙本质基质所构成的天然矿化环境诱导下,迅速在脱矿牙本质基质的极性位点形成的大量ACP纳米颗粒,这些化学结合的无机纳米粒子掩蔽了脱矿牙本质基质的极性,消除牙本质有机质的水化能力,改善粘接界面的脱矿牙本质基质相和粘接剂相的相容性;提高其机械强度,抵抗水挥发时导致的塌陷,从而摆脱牙本质粘接时对水的依赖性,降低临床粘接操作的敏感性和由水残留导致的混合层的不稳定性,可制备为一种牙科粘接预处理剂,适用于口腔所有粘接剂场合。