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公开(公告)号：WO2023091391A1
公开(公告)日：2023-05-25
申请号：PCT/US2022/049906
申请日：2022-11-15
摘要： An interferential cuff electrode includes an annular body configured to be positioned at least partially around a nerve in a patient. The interferential cuff electrode also includes a plurality of contacts coupled to the body. The contacts are configured to apply first and second demodulated signals to the nerve. The first and second demodulated signals differ from one another by an interference frequency, a phase, or both. The first and second demodulated signals are configured to stimulate the nerve at the interference frequency.
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公开(公告)号：WO2023089428A1
公开(公告)日：2023-05-25
申请号：PCT/IB2022/060476
申请日：2022-10-31
申请人： COCHLEAR LIMITED
摘要： Presented herein are techniques for managing heat generated by a wearable device, such as an external component of an implantable device system. The wearable device is configured to be worn by a user and operates within an insulated environment. The techniques presented herein use one or more thermally conductive members to receive heat generated by the wearable device and to transfer heat from the wearable device to a location outside of the insulated environment.
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公开(公告)号：WO2023088766A1
公开(公告)日：2023-05-25
申请号：PCT/EP2022/081413
申请日：2022-11-10
发明人： KOLBERG, Gernot , DOHMEN, Daniel , HILLEBRAND, Gordon , FELDMANN, Joerg , BUCHER, Dagmar , HINRICHSEN, Lisa
摘要： An implantable medical device (1) for implantation into a patient comprises a body (100, 150) having a distal end (101, 151) and an electrode device (14) for at least one of emitting an electrical stimulation signal and sensing an electrical sense signal, said electrode device (14) being arranged at said distal end (101, 151) of the body (100, 150) and comprising a helix element (142) to be screwed into tissue. A blade section (16) is configured to cut into tissue when said helix element (142) is screwed into tissue.
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公开(公告)号：WO2023077014A1
公开(公告)日：2023-05-04
申请号：PCT/US2022/078802
申请日：2022-10-27
发明人： CLAWSON, Corbin , SHAH, Jimmy , PIERCE, Wilbert
摘要： A low-profile cranial device is adapted for covering and protecting electrical leads. The cranial device includes a static cranial implant shaped and dimensioned for housing a functional neurosurgical implant including electrical leads. The static cranial implant includes an outer first surface along an exterior side of the static cranial implant, an inner second surface along an interior side of the static cranial implant, and a peripheral wall extending between the outer first surface and the inner second surface. A cavity is formed along the outer first surface of the static cranial implant, the cavity being shaped and dimensioned to house the functional neurosurgical implant in a manner allowing the electrical leads to be wound up to store excess electrical lead length.
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公开(公告)号：WO2023075912A1
公开(公告)日：2023-05-04
申请号：PCT/US2022/041658
申请日：2022-08-26
摘要： Controlled heating can be used to achieve selective nerve block of certain neural fibers. As an example, the selective heat-induced neural modulation can be used for pain management. A controller can determine an amount of energy to be delivered to a heat delivery component of a neural prosthetic device for conversion to a heat signal and application to a nerve to block neural conduction in at least a portion of the nerve. The amount of energy to be delivered is determined based on a thermal dose profile. The controller can receive a signal comprising a temperature of the nerve when the heat signal is applied to the nerve; and alter the amount of energy received by the heat delivery component based on the temperature of the nerve so the amount of energy follows the thermal dose profile, and the temperature of the nerve remains within an allowable range.
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6.发明申请
公开(公告)号：WO2023069940A1
公开(公告)日：2023-04-27
申请号：PCT/US2022/078288
申请日：2022-10-18
发明人： CHOI, Kyuwan , ROSS, Erika , WHITMER, Diane
摘要： The present disclosure provides systems and methods for providing neurostimulation therapy using multi-dimensional patient features. The multi-dimensional patient features may include features in respective frequency bands for selected cortical sites from EEG localization data. Additionally or alternatively, the multi-dimensional patient features may include features from patient physiological data or other patient activity data. The multi-dimensional feature data may be compared against AI/ML models of patient and/or healthy population members. Closed-loop therapy adjustments may be applied to a respective patient's neurostimulation therapy using the multi-dimensional patient feature analysis.
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7.发明申请
公开(公告)号：WO2023069848A1
公开(公告)日：2023-04-27
申请号：PCT/US2022/077915
申请日：2022-10-11
发明人： ANNECCHINO, Luca, A. , DOAN, Que
摘要： Methods and systems for providing electrical stimulation to a patient's spinal cord using electrode leads implanted in the patient's spinal column are described. Embodiments involve biphasic stimulation where during a first phase a first pole provides stimulation to a first location and during a second phase a second pole provides stimulation to a second location. The two phases may have the same or different amplitudes. The amplitudes of the two phases may be determined based on perception thresholds for stimulation at the two locations.
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公开(公告)号：WO2023057341A1
公开(公告)日：2023-04-13
申请号：PCT/EP2022/077346
申请日：2022-09-30
发明人： TAFF, Brian M. , MUESSIG, Dirk , WHITTINGTON, R. Hollis , AUSTIN, Eric , HUGHES, Devan , MIDGETT, Madeline Anne
IPC分类号： A61N1/05 , A61N1/375 , A61N1/372 , A61N1/0573 , A61N1/37205 , A61N1/37516 , A61N1/3756
摘要： The present invention relates to a method for fixing of an intracardiac device at an anchoring region within the tissue of a patient's heart is described which allows fixing at a thin wall, wherein the intracardiac device comprises one electrode (24) and at least two tines (30) attached at a distal end of the intra-cardiac device adjacent the electrode (24), wherein each of the at least two tines (30) has an S-form with the furthest distal end section pointing inwards, is pivotable outwards around a bending point at its proximal end and/or bendable and is preloaded inwards, comprising the following steps:- the intra-cardiac device is moved towards the anchoring region (arrow P1) with the at least two tines (30) facing forwards until the at least two tines touch the tissue at the anchoring region, - then, the at least two tines (30) are pressed against the tissue at the anchoring region (arrow P2) such that the at least two tines (30) are pivoted outwards and/or bent outwards, thereby the distal ends of the at least two tines penetrate into the tissue, and,- afterwards, the pressure on the tines (3) is against the tissue is removed, thereby bunching a wall segment (11) of the tissue by the at least two tines and pulling this wall segment (11) towards the electrode (24). Further, a respective intracardiac device is disclosed.
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公开(公告)号：WO2023049145A1
公开(公告)日：2023-03-30
申请号：PCT/US2022/044193
申请日：2022-09-21
发明人： RUBIN, Joseph, Peter
摘要： A cranial electronics device includes electronics and a flexible body via which the electronics are carried. The flexible body and the electronics are formed such that the device has a lower surface approximating a contour of an outer surface of a portion of a patient's skull. The cranial electronics device is configured to be implanted between the patient's scalp and the portion of patient's skull.
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公开(公告)号：WO2023043652A1
公开(公告)日：2023-03-23
申请号：PCT/US2022/042868
申请日：2022-09-08
发明人： KRYZANSKI, James
摘要： Disclosed are devices, electrodes, systems, methods, and other implementations, including a subdural sound that includes an elongated body configured to be placed within a subdural space of a brain area of a patient, with the elongated body defining a receiving channel to receive a displaceable electrode to be tangentially placed at a target site in the subdural space. The subdural sound further includes a curved tip at a distal end of the elongated body, the curved tip configured for angled insertion into the subdural space of the patient to advance the elongated body to the target site in the subdural space.
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