公开(公告)号：WO2023085884A1

公开(公告)日：2023-05-19

申请号：PCT/KR2022/017890

申请日：2022-11-14

Applicant: (주)피앤피바이오팜

Inventor： 신항철 ,  김대영 ,  박연희 ,  권용현 ,  유지원 ,  송정훈

IPC: C07K14/50 ,  C12N15/63 ,  A61K38/18 ,  A61P17/14 ,  A61P17/02 ,  A61K8/64 ,  A61Q5/02 ,  A61Q7/00

Abstract: 본 발명은 안정성이 증가된 인간 각질세포 성장인자1 변이체 및 이의 용도에 관한 것으로, 본 발명에 따른 KGF1 변이체는 열 안정성과 수용액 상태에서의 안정성이 천연형 KGF1에 비하여 현저히 우수하면서도, 치료활성은 동일하므로, KGF1 변이체를 함유하는 치료용 의약품 또는 기능성 화장품은 유통과 보관과정 중에서도 활성을 유효하게 오랫동안 유지될 수 있다.제1항의 고안정성 KGF1 변이체를 유효성분으로 함유하는 탈모 방지 또는 개선용 모발 세정용 조성물.

公开(公告)号：WO2023085135A1

公开(公告)日：2023-05-19

申请号：PCT/JP2022/040556

申请日：2022-10-28

Applicant: エルデシエロ　プライベート　リミテッド

Inventor： 庄野　裕介 ,  マイティ　ビムチャラン

IPC: C07C405/00 ,  A61K8/30 ,  A61K31/5575 ,  A61P17/14 ,  A61P27/02 ,  A61Q7/00 ,  C07C69/734 ,  C07D307/935

Abstract: 本発明の少なくとも１つの目的は、新規な化合物を提供することである。　化学式（ｉ）： ［式中、平行な破線と実線で示した結合は、単結合、又はシス配置もしくはトランス配置をとることができる二重結合を表し、Ｒ１及びＲ２は、それぞれ、水素、炭素数１～６のアルキル基、炭素数３～８のシクロアルキル基、炭素数６～８のアリール基、又はＲ４－Ｃ（＝Ｏ）－を表し、Ｒ４は炭素数１～６のアルキル基であり、Ｒ３は、水素、炭素数１～６のアルキル基、炭素数３～８のシクロアルキル基、又は炭素数６～８のアリール基を表す。］で表される化合物。

公开(公告)号：WO2023043111A1

公开(公告)日：2023-03-23

申请号：PCT/KR2022/013364

申请日：2022-09-06

Applicant: 코스맥스 주식회사

Inventor： 백채윤 ,  이동걸 ,  경서연 ,  강승현 ,  박명삼

IPC: C12N1/20 ,  A61K8/99 ,  A61Q7/00 ,  A61K35/74 ,  A61P17/14 ,  A23L33/135 ,  C12R1/01

Abstract: 신규한 미생물, 그의 파쇄액, 배양액, 추출액, 및 이들의 모발 또는 두피 상태 개선 용도에 관한 것이다. 일 양상에 따른 신규 파라코커스 데니트리피칸스 균주에 의하면, 발모 촉진, 탈모 방지, 및 모근 강화 효과가 있으므로, 모발 또는 두피 상태의 개선, 예방, 또는 치료 용도로 다양하게 응용될 수 있다. 또한, 상기 균주를 스타필로코커스 에피덜미디스 균주 및 효모 추출물 중 어느 하나 이상과 조합하여 사용할 경우, 모발 또는 두피 상태의 개선에 시너지 효과를 나타낼 수 있다.

公开(公告)号：WO2023031002A1

公开(公告)日：2023-03-09

申请号：PCT/EP2022/073635

申请日：2022-08-25

Applicant: CLARIANT INTERNATIONAL LTD

Inventor： FRECHET, Mathilde ,  CHAJRA, Hanane ,  GARANDEAU, David ,  ROH, Kyung Baeg ,  JUNG, Eun Sun ,  PARK, Deok Hoon

IPC: A61K8/9789 ,  A61K8/9783 ,  A61Q19/00 ,  A61Q7/00 ,  A61P17/14 ,  A61K31/00 ,  A61K8/34 ,  A61K8/36 ,  A61K36/536

Abstract: The present invention relates to an extract of the aerial parts of Prunella vulgaris targeting the psycho-emotional stress that is responsible for the aggravation of the skin and the hair conditions. Preferably, the present invention relates to the use of a composition comprising or consisting of the aerial parts of Prunella vulgaris intended for preventing and/or treating the psychoemotional stress related disorders and/or damages on the skin and the hair follicles.

公开(公告)号：WO2023018694A1

公开(公告)日：2023-02-16

申请号：PCT/US2022/039800

申请日：2022-08-09

Applicant: REVELA, INC.

Inventor： BOPPANA, Avinash ,  ZHANG, Kongyu ,  ZHAO, Evan ,  COLEY, Connor Wilson ,  LEE, Elizabeth ,  HUA, Tiffany ,  LE, Amy

IPC: A61Q5/002 ,  A61K8/41 ,  A61K8/30 ,  A61Q7/00 ,  A61K8/40 ,  A61Q5/00

Abstract: Compositions and formulations for hair treatment are provided herein. Methods for hair treatment, such as methods for preventing or treating hair loss or hair thinning, are also provided herein. The methods may promote hair growth, hair restoration or hair thickening, or increase hair density or hair growth rate.

公开(公告)号：WO2022269111A1

公开(公告)日：2022-12-29

申请号：PCT/ES2022/070365

申请日：2022-06-10

Applicant: LABORATORIOS SERRA PAMIES, S.A.

Inventor： JOFRE SOLANELLAS, Marta

IPC: A61Q5/00 ,  A61Q7/00 ,  A61K8/9794 ,  A61K8/9789 ,  A61K8/9711 ,  A61P17/14

Abstract: La invención consiste en un tratamiento cosmético previsto para ser aplicado durante y después de tratamientos oncológicos, en orden a prevenir, paliar y mejorar los efectos secundarios y síntomas que el tratamiento oncológico provoca en el cabello y la piel del cuero cabelludo. El tratamiento cosmético de la invención se constituye a partir de tres productos que deben ser aplicados sobre los pacientes, compuestos por un fluido calmante, una mousse capilar de lavado, y por último una loción regeneradora, capaces de minimizar los efectos secundarios de la quimioterapia y ayudar al crecimiento del nuevo cabello en las mejores condiciones.

公开(公告)号：WO2022268971A1

公开(公告)日：2022-12-29

申请号：PCT/EP2022/067210

申请日：2022-06-23

Applicant: CHARITÉ - UNIVERSITÄTSMEDIZIN BERLIN ,  PHILIPPS UNIVERSITÄT MARBURG

Inventor： LADEMANN, Jürgen ,  MEINKE, Martina ,  KLEIN, Anna-Lena ,  BUSCH, Loris ,  KECK, Cornelia ,  PELIKH, Olga

IPC: A61K9/14 ,  A61K31/436 ,  A61K31/506 ,  A61K31/522 ,  A61K31/573 ,  A61K31/58 ,  A61K31/7088 ,  A61K38/13 ,  A61K8/02 ,  A61K8/35 ,  A61K8/49 ,  A61P17/14 ,  A61Q7/00 ,  A61Q19/00 ,  A61K9/00 ,  A61K2800/412 ,  A61K2800/652 ,  A61K8/0241 ,  A61K8/498 ,  A61K8/4993 ,  A61K9/0014 ,  A61K9/145

Abstract: The invention relates to a composition for the transport of a dissolved active agent into hair follicles, comprising an active agent dissolved in a topical dispersion medium, and submicron particles. In one aspect, the invention relates to a pharmaceutical composition for use in transporting a dissolved pharmacologically active therapeutical and/or prophylactic agent into hair follicles comprising a pharmacologically active therapeutic and/or prophylactic agent dissolved in a topical dispersion medium, and submicron particles. In embodiments, the active agent is not chemically coupled to the submicron particles. In a further aspect, the composition is a cosmetic composition comprising a cosmetically active agent, and the cosmetic composition can be used in a cosmetic method, wherein the cosmetic composition is applied to an area of skin with hair follicles.

公开(公告)号：WO2022251277A1

公开(公告)日：2022-12-01

申请号：PCT/US2022/030805

申请日：2022-05-25

Applicant: FIGENE, LLC

Inventor： ICHIM, Thomas ,  O'HEERON, Pete

IPC: A61P17/14 ,  A61K38/16 ,  A61K8/64 ,  A61K38/17 ,  A61Q7/00

Abstract: Disclosed herein are methods and compositions for treatment and prevention of alopecia, including alopecia areata. Aspects are directed to methods for stimulating or accelerating hair follicle regeneration. Certain aspects are directed to methods for treating alopecia areata comprising administration of fibroblasts and/or a fibroblast derived product to a subject suffering from alopecia areata. In some cases, a fibroblast derived product is conditioned media, exosomes, or apoptotic bodies from fibroblasts, formulated for topical use for treatment or prevention of alopecia areata.

公开(公告)号：WO2022216071A1

公开(公告)日：2022-10-13

申请号：PCT/KR2022/005000

申请日：2022-04-07

Applicant: 차의과학대학교 산학협력단

Inventor： 정지형 ,  나영화 ,  정훈택 ,  최지환

IPC: C07D501/57 ,  C07D501/02 ,  A61K31/546 ,  A61P17/14 ,  A61K8/49 ,  A61Q7/00

Abstract: 본 발명은 세팔로틴 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법, 및 이를 포함하는 탈모방지 또는 발모촉진용 조성물을 제공한다.

公开(公告)号：WO2022180651A1

公开(公告)日：2022-09-01

申请号：PCT/IT2021/000007

申请日：2021-02-25

Applicant: ANTONUCCI TAROLLA, Nicola Tito Pierluca

Inventor： ANTONUCCI TAROLLA, Nicola Tito Pierluca

IPC: A61K8/365 ,  A61K8/368 ,  A61K8/49 ,  A61K8/60 ,  A61K8/9789 ,  A61K31/192 ,  A61K31/352 ,  A61K31/353 ,  A61K31/366 ,  A61K31/70 ,  A61K36/185 ,  A61P17/14 ,  A61Q7/00 ,  A61Q19/08

Abstract: The present invention refers to a composition comprising one or more ellagitannin, one or more phenolic acid, one or more flavonoid, wherein: said one or more ellagitannin is selected from the group consisting of: castalagin, agrimoniin, vescalagin, and mixture thereof; said one or more phenolic acid is selected from the group consisting of: caffeic acid, ellagic acid, gallic acid, p-coumaric acid, ad mixture thereof; said one or more flavonoids are selected from the group consisting of: cyaniding, procyanidin, quercetin, catechin, epicatechin, kaempferol, delphinidin, pelargonidin, peonidin and mixture thereof. The present invention refers to a cosmetic use of the composition of the present invention for stimulating hair growth and/or preventing or treating hair loss and/or for skin anti-age effect. The present invention refers to the composition of the present invention for use in the prevention and/or treating of skin disorders and/or alopecia. The present invention refers to the composition of the present invention, wherein said composition is in a form for oral administration or topic application.