公开(公告)号：WO2022104136A2

公开(公告)日：2022-05-19

申请号：PCT/US2021/059240

申请日：2021-11-12

Applicant: CHILDREN'S MEDICAL CENTER CORPORATION

Inventor： STEEN, Judith AJ ,  STEEN, Hanno ,  WESSELING, Hendrik ,  KUMAR, Mukesh ,  MAIR, Waltraud ,  BEEREPOOT, Pieter

IPC: C12Q1/37 ,  G01N30/72 ,  G01N33/68 ,  G01N2333/4709 ,  G01N2440/10 ,  G01N2440/14 ,  G01N2440/36 ,  G01N2800/2821 ,  G01N33/6896

Abstract: This disclosure relates to methods for diagnosing and treating a tauopathy, e.g., Alzheimer's disease, in a subject, the methods comprising, in part, identifying one or more post-translation modifications (PTMs) in the subject.