-
公开(公告)号：WO2023288047A2
公开(公告)日：2023-01-19
申请号：PCT/US2022/037262
申请日：2022-07-15
Applicant: ALNYLAM PHARMACEUTICALS, INC.
Inventor： MANOHARAN, Muthiah , DATTA, Dhrubajyoti
IPC: A61K31/7008 , A61K31/7052 , A61K31/7056 , C07H19/056 , C08K5/28 , A61K47/26
Abstract: The present disclosure relates to monomers and methods for conjugating one or more ligands to oligonucleotides by Click chemistry through attachment of azido group or triazolyl moiety at the anomeric site of pentose or hexose sugars. Another aspect the invention relates to a method of modulating the expression of a target gene in a cell, comprising administering to said cell an oligonucleotide and/or dsRNA molecule described herein.
-
公开(公告)号：WO2022260335A1
公开(公告)日：2022-12-15
申请号：PCT/KR2022/007721
申请日：2022-05-31
Applicant: 쿼럼바이오 주식회사
IPC: A61K31/7008 , A61P43/00 , A61P3/04 , A23L33/125 , A23K20/163
Abstract: 갈락토오스를 포함하는 장내 미생물 개체군 개선용, 체중 감소용 약학 조성물 식품 조성물, 또는 사료 조성물, 및 이의 비만의 예방 및/또는 치료 및/또는 개선에 사용하기 위한 용도가 제공된다.
-
公开(公告)号：WO2022238886A1
公开(公告)日：2022-11-17
申请号：PCT/IB2022/054324
申请日：2022-05-10
Applicant: M-SQUARED CONSULTING S.R.L.
Inventor： BACCHI, Fabrizio , LATINO, Massimo , BELLASI, Manuel
IPC: A61K31/135 , A61K31/7008 , A61K45/06 , A61P31/14
Abstract: The present invention relates to Cyclobenzaprine, salts thereof or metabolites thereof for use in the treatment of diseases related to Coronavirus infections. In particular, the present invention is directed to Cyclobenzaprine or pharmaceutically acceptable salts thereof and/or metabolites thereof or mixtures of said compounds for use in the treatment of Coronavirus infections.
-
公开(公告)号：WO2022051575A2
公开(公告)日：2022-03-10
申请号：PCT/US2021/048991
申请日：2021-09-03
Applicant: HASSAN, Ameer E. , KHALILI, Yousef Hasan Ahmad
Inventor： HASSAN, Ameer E. , KHALILI, Yousef Hasan Ahmad
IPC: A61F13/00 , A61K31/726 , A61K47/18 , A61K31/7008
Abstract: The present disclosure relates to compounds and methods for treating symptoms or sequelae resulting from viral infection, including influenza, rhinovirus, or betacoronavirus infection, such as human coronaviruses such as SARS coronaviruses, MERS coronaviruses, and COVID-19, including Acute Respiratory Distress Syndrome (ARDS) associated with the viral infection.
-
公开(公告)号：WO2021155748A1
公开(公告)日：2021-08-12
申请号：PCT/CN2021/073697
申请日：2021-01-26
Applicant: TSINGHUA UNIVERSITY
Inventor： YAN, Nieng , SHI, Yigong , YIN, Hang , JIANG, Xin , YUAN, Yafei , HUANG, Jian
IPC: A61K31/7008 , A61K31/4745 , C07D309/14
Abstract: Provided are molecules capable of binding to binding pockets of Plasmodium falciparum hexose transporter (PfHT) or analogs thereof and complexes comprising the same. Also provided herein are inhibitors of PfHT, pharmaceutical compositions comprising the inhibitors, and methods of using the inhibitors or the pharmaceutical compositions in the treatment of diseases associated with Plasmodium or PfHT or the killing or inhibiting the growth of Plasmodium. Provided are a set of structure coordinates of such binding pockets and method of using the set of structure coordinates to screen for and design compounds that are capable of binding to PfHT or analogs thereof.
-
Patent Agency Ranking
公开(公告)号：WO2021062888A1
公开(公告)日：2021-04-08
申请号：PCT/CN2019/111794
申请日：2019-10-18
Applicant: 青岛琛蓝医药科技发展有限公司 , 美国琛蓝营养制品股份有限公司
IPC: A23L33/105 , A23L33/125 , A23L33/17 , A61K38/39 , A61P19/02 , A61P29/00 , A61K31/7008 , A61K31/737 , A61K36/8945
Abstract: 一种具有促进骨关节健康作用的复方组合物及其应用，通过将氨糖与胶原、硫酸软骨素、中药提取物进行结合才得以制备出一种具有促进骨关节健康作用的复方组合物，该复方组合物可以缩短起效时间，同时可作为膳食补充剂或保健食品原料，用于预防或者治疗中轻度骨关节炎。
-
公开(公告)号：WO2020157570A1
公开(公告)日：2020-08-06
申请号：PCT/IB2020/000053
申请日：2020-01-31
Applicant: I.COM MEDICAL GMBH
IPC: A61P27/04 , A61P29/02 , A61K31/7008
Abstract: The invention concerns a method for relieving idiopathic ocular pain by administering an effective amount of a fluid composition comprising hyaluronic acid, a hyaluronic acid analogue, or a combination thereof, to the eye of a human or non-human animal subject, wherein the fluid composition is administered after onset of the idiopathic ocular pain and in the absence of detectable signs known to cause ocular pain.
-
公开(公告)号：WO2020106099A1
公开(公告)日：2020-05-28
申请号：PCT/KR2019/016141
申请日：2019-11-22
Applicant: (주)프로스테믹스
IPC: C12N1/14 , C12N1/20 , A23L33/10 , C12Q1/02 , A61K8/60 , A61K8/73 , A61K31/7008 , A61K35/74 , G01N33/50 , A61P1/00
Abstract: 본 발명은 글루코사민(glucosamine), 글루코사민 유도체 또는 이의 염을 포함하는 신규한 엑소좀에 관한 것이다. 본 발명에서 제공하는 엑소좀은 항염증 효과가 뛰어나 다양한 염증성 질환을 효과적으로 예방, 개선 또는 치료할 수 있고, 그 외에도 장 질환의 치료, 피부 개선, 상처 치료 또는 탈모 치료 효과가 뛰어나다.
-
公开(公告)号：WO2020030571A1
公开(公告)日：2020-02-13
申请号：PCT/EP2019/070979
申请日：2019-08-05
Inventor： HUG, Bruce, A , MATHENY, Christopher, J
IPC: A61K39/395 , A61K31/00 , A61K31/7008 , A61K31/7028 , A61K45/00 , A61K45/06 , C07K16/28 , A61K39/00
Abstract: Disclosed herein are combinations of a PD-1 binding protein, and a TLR4 modulator, such as a TLR4 agonist, pharmaceutical compositions thereof, uses thereof, and methods of treatment comprising administering said combination, including uses in cancer.
-
公开(公告)号：WO2020014776A1
公开(公告)日：2020-01-23
申请号：PCT/CA2019/050976
申请日：2019-07-15
Applicant: RAPID DOSE THERAPEUTICS CORP.
Inventor： MACPHAIL, Benjamin James , CARLINI, Rina , LEWIS, James , KAPTEYN, Emily Quinn
IPC: A61K9/70 , A61K31/05 , A61K31/12 , A61K31/122 , A61K31/192 , A61K31/202 , A61K31/352 , A61K31/4045 , A61K31/465 , A61K31/522 , A61K31/593 , A61K31/7008 , A61K31/714 , A61K33/26 , A61K47/36 , C07C39/08 , C07C39/19 , C07C39/23 , C07C401/00 , C07C43/295 , C07C50/28 , C07C57/03 , C07C65/05 , C07C65/19 , C07D209/16 , C07D311/74 , C07D311/80 , C07D401/04 , C07D473/12 , C07H23/00
Abstract: An oral dispersible film composition comprising at least one active ingredient and a film forming agent, as well as a method of manufacture of same. The oral dispersible film composition can be free of gum resin, and can be utilized to administer various active ingredients, including cannabinoids.
-
-
-
-
-
-
-
-
-
Search Results
453
records
(took 0.042 seconds)
